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Published in: BMC Neurology 1/2022

Open Access 01-12-2022 | Parkinson's Disease | Research article

Novel insights regarding the measurement properties of the SCOPA-AUT

Authors: Albert Westergren, Klas Wictorin, Oskar Hansson, Peter Hagell

Published in: BMC Neurology | Issue 1/2022

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Abstract

Background

The Scale for Outcomes in Parkinson’s disease for Autonomic symptoms (SCOPA-AUT) is an instrument intended to assess overall and domain-specific autonomic symptom burden. In this study the SCOPA-AUT is translated into Swedish and its measurement properties are assessed.

Methods

Following translation the SCOPA-AUT was field-tested regarding comprehensibility, relevance, and respondent burden (n = 20). It was then tested according to Rasch measurement theory using data from 242 persons with PD, of whom 162 completed SCOPA-AUT at baseline and 1–2 years later, giving a total of 404 data points for analysis.

Results

The Swedish SCOPA-AUT took a mean of 6 min to complete and was considered easy to use and relevant by respondents. SCOPA-AUT exhibited acceptable Rasch model fit, represents more severe levels of dysautonomia than that reported by the sample, and response categories were not working as expected for 17 items. Local dependency was identified and followed a pattern resembling the suggested subscales. Accounting for the subscale structure eliminated local dependency and reduced the initially inflated reliability from 0.81 to 0.68.

Conclusions

The SCOPA-AUT is useful as a clinical check-list but requires further developmental work in order to meet more rigorous standards as an outcome measurement instrument.
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Literature
1.
go back to reference Marras C, Chaudhuri KR. Nonmotor features of Parkinson’s disease subtypes. Mov Disord. 2016;31(8):1095–102.CrossRef Marras C, Chaudhuri KR. Nonmotor features of Parkinson’s disease subtypes. Mov Disord. 2016;31(8):1095–102.CrossRef
2.
go back to reference Sjodahl Hammarlund C, Nilsson MH, Hagell P. Measuring outcomes in Parkinson’s disease: a multi-perspective concept mapping study. Qual Life Res. 2012;21(3):453–63.CrossRef Sjodahl Hammarlund C, Nilsson MH, Hagell P. Measuring outcomes in Parkinson’s disease: a multi-perspective concept mapping study. Qual Life Res. 2012;21(3):453–63.CrossRef
3.
go back to reference Seppi K, Ray Chaudhuri K, Coelho M, Fox SH, Katzenschlager R, Perez Lloret S, Weintraub D, Sampaio C. the collaborators of the Parkinson’s Disease Update on Non-Motor Symptoms Study Group on behalf of the Movement Disorders Society Evidence-Based Medicine C. Update on treatments for nonmotor symptoms of Parkinson’s disease-an evidence-based medicine review. Mov Disord. 2019;34(2):180–98.CrossRef Seppi K, Ray Chaudhuri K, Coelho M, Fox SH, Katzenschlager R, Perez Lloret S, Weintraub D, Sampaio C. the collaborators of the Parkinson’s Disease Update on Non-Motor Symptoms Study Group on behalf of the Movement Disorders Society Evidence-Based Medicine C. Update on treatments for nonmotor symptoms of Parkinson’s disease-an evidence-based medicine review. Mov Disord. 2019;34(2):180–98.CrossRef
4.
go back to reference Visser M, Marinus J, Stiggelbout AM, Van Hilten JJ. Assessment of autonomic dysfunction in Parkinson’s disease: the SCOPA-AUT. Mov Disord. 2004;19(11):1306–12.CrossRef Visser M, Marinus J, Stiggelbout AM, Van Hilten JJ. Assessment of autonomic dysfunction in Parkinson’s disease: the SCOPA-AUT. Mov Disord. 2004;19(11):1306–12.CrossRef
5.
go back to reference Carod-Artal FJ, Ribeiro Lda S, Kummer W, Martinez-Martin P. Psychometric properties of the SCOPA-AUT Brazilian Portuguese version. Mov Disord. 2010;25(2):205–12.CrossRef Carod-Artal FJ, Ribeiro Lda S, Kummer W, Martinez-Martin P. Psychometric properties of the SCOPA-AUT Brazilian Portuguese version. Mov Disord. 2010;25(2):205–12.CrossRef
6.
go back to reference Rodriguez-Blazquez C, Forjaz MJ, Frades-Payo B, de Pedro-Cuesta J, Martinez-Martin P. Longitudinal Parkinson’s Disease Patient Study ELdPcEdPG: Independent validation of the scales for outcomes in Parkinson’s disease-autonomic (SCOPA-AUT). Eur J Neurol. 2010;17(2):194–201.CrossRef Rodriguez-Blazquez C, Forjaz MJ, Frades-Payo B, de Pedro-Cuesta J, Martinez-Martin P. Longitudinal Parkinson’s Disease Patient Study ELdPcEdPG: Independent validation of the scales for outcomes in Parkinson’s disease-autonomic (SCOPA-AUT). Eur J Neurol. 2010;17(2):194–201.CrossRef
7.
go back to reference Verbaan D, Marinus J, Visser M, van Rooden SM, Stiggelbout AM, van Hilten JJ. Patient-reported autonomic symptoms in Parkinson disease. Neurology. 2007;69(4):333–41.CrossRef Verbaan D, Marinus J, Visser M, van Rooden SM, Stiggelbout AM, van Hilten JJ. Patient-reported autonomic symptoms in Parkinson disease. Neurology. 2007;69(4):333–41.CrossRef
8.
go back to reference Rasch G. Probabilistic Models for Some Intelligence and Attainment Tests. Copenhagen: Danish Institute for Educational Research; 1960. Rasch G. Probabilistic Models for Some Intelligence and Attainment Tests. Copenhagen: Danish Institute for Educational Research; 1960.
9.
go back to reference Andrich D, Marais I. A course in Rasch measurement theory: measuring in the educational, social and health sciences: Springer; 2019. Andrich D, Marais I. A course in Rasch measurement theory: measuring in the educational, social and health sciences: Springer; 2019.
10.
go back to reference Hobart JC, Cano SJ, Zajicek JP, Thompson AJ. Rating scales as outcome measures for clinical trials in neurology: problems, solutions, and recommendations. Lancet Neurol. 2007;6(12):1094–105.CrossRef Hobart JC, Cano SJ, Zajicek JP, Thompson AJ. Rating scales as outcome measures for clinical trials in neurology: problems, solutions, and recommendations. Lancet Neurol. 2007;6(12):1094–105.CrossRef
11.
go back to reference Forjaz MJ, Ayala A, Rodriguez-Blazquez C, Frades-Payo B, Martinez-Martin P. Longitudinal Parkinson’s Disease Patient Study EldpcedP-EG. Assessing autonomic symptoms of Parkinson’s disease with the SCOPA-AUT: a new perspective from Rasch analysis. Eur J Neurol. 2010;17(2):273–9.CrossRef Forjaz MJ, Ayala A, Rodriguez-Blazquez C, Frades-Payo B, Martinez-Martin P. Longitudinal Parkinson’s Disease Patient Study EldpcedP-EG. Assessing autonomic symptoms of Parkinson’s disease with the SCOPA-AUT: a new perspective from Rasch analysis. Eur J Neurol. 2010;17(2):273–9.CrossRef
12.
go back to reference Swaine-Verdier A, Doward LC, Hagell P, Thorsen H, McKenna SP. Adapting quality of life instruments. Value Health. 2004;7(Suppl 1):S27-30.CrossRef Swaine-Verdier A, Doward LC, Hagell P, Thorsen H, McKenna SP. Adapting quality of life instruments. Value Health. 2004;7(Suppl 1):S27-30.CrossRef
13.
go back to reference Gelb DJ, Oliver E, Gilman S. Diagnostic criteria for Parkinson disease. Arch Neurol. 1999;56(1):33–9.CrossRef Gelb DJ, Oliver E, Gilman S. Diagnostic criteria for Parkinson disease. Arch Neurol. 1999;56(1):33–9.CrossRef
14.
go back to reference Lindskov S, Sjoberg K, Hagell P, Westergren A. Weight stability in Parkinson’s disease. Nutr Neurosci. 2016;19(1):11–20.CrossRef Lindskov S, Sjoberg K, Hagell P, Westergren A. Weight stability in Parkinson’s disease. Nutr Neurosci. 2016;19(1):11–20.CrossRef
15.
go back to reference Hoehn MM, Yahr MD. Parkinsonism: onset, progression and mortality. Neurol. 1967;17(5):427–42.CrossRef Hoehn MM, Yahr MD. Parkinsonism: onset, progression and mortality. Neurol. 1967;17(5):427–42.CrossRef
16.
go back to reference Andrich D, Luo G, Sheridan B. Rumm 2030: Rasch Unidimensional Measurement Models (software). Perth, Western Australia: RUMM Laboratory; 2012. Andrich D, Luo G, Sheridan B. Rumm 2030: Rasch Unidimensional Measurement Models (software). Perth, Western Australia: RUMM Laboratory; 2012.
17.
go back to reference Hobart J, Cano S. Improving the evaluation of therapeutic interventions in multiple sclerosis: the role of new psychometric methods. Health Technol Assess 2009;13(12):iii, ix-x:1–177. Hobart J, Cano S. Improving the evaluation of therapeutic interventions in multiple sclerosis: the role of new psychometric methods. Health Technol Assess 2009;13(12):iii, ix-x:1–177.
18.
go back to reference Kyngdon A. Is Combining Samples Productive? A Quick Check via Tests of DIF. Rasch Meas Trans. 2011;25(2):1324–5. Kyngdon A. Is Combining Samples Productive? A Quick Check via Tests of DIF. Rasch Meas Trans. 2011;25(2):1324–5.
19.
go back to reference Wright B, Masters G. Rating scale analysis. Chicago: Mesa Press; 1982. Wright B, Masters G. Rating scale analysis. Chicago: Mesa Press; 1982.
20.
go back to reference Christensen KB, Makransky G, Horton M. Critical Values for Yen’s Q3: Identification of Local Dependence in the Rasch Model Using Residual Correlations. Appl Psychol Meas. 2017;41(3):178–94.CrossRef Christensen KB, Makransky G, Horton M. Critical Values for Yen’s Q3: Identification of Local Dependence in the Rasch Model Using Residual Correlations. Appl Psychol Meas. 2017;41(3):178–94.CrossRef
21.
go back to reference Hagell P. Testing Rating Scale Unidimensionality Using the Principal Component Analysis (PCA)/t-Test Protocol with the Rasch Model: The Primacy of Theory over Statistics. Open J Stat. 2014;4:456–65.CrossRef Hagell P. Testing Rating Scale Unidimensionality Using the Principal Component Analysis (PCA)/t-Test Protocol with the Rasch Model: The Primacy of Theory over Statistics. Open J Stat. 2014;4:456–65.CrossRef
22.
go back to reference Smith EV Jr. Detecting and evaluating the impact of multidimensionality using item fit statistics and principal component analysis of residuals. J Appl Meas. 2002;3(2):205–31. Smith EV Jr. Detecting and evaluating the impact of multidimensionality using item fit statistics and principal component analysis of residuals. J Appl Meas. 2002;3(2):205–31.
23.
go back to reference Salzberger T. The validity of polytomous items in the Rasch model–The role of statistical evidence of the threshold order. Psychol Test Assess Model. 2015;3:377–95. Salzberger T. The validity of polytomous items in the Rasch model–The role of statistical evidence of the threshold order. Psychol Test Assess Model. 2015;3:377–95.
24.
go back to reference Adams RJ, Wu ML, Wilson M. The Rasch Rating Model and the Disordered Threshold Controversy. Educ Psychol Meas. 2012;72(4):547–73.CrossRef Adams RJ, Wu ML, Wilson M. The Rasch Rating Model and the Disordered Threshold Controversy. Educ Psychol Meas. 2012;72(4):547–73.CrossRef
25.
go back to reference Andrich D. Implications and applications of modern test theory in the context of outcomes based education. Stud Educ Eval. 2002;28(2):103.CrossRef Andrich D. Implications and applications of modern test theory in the context of outcomes based education. Stud Educ Eval. 2002;28(2):103.CrossRef
26.
go back to reference Andrich D. An Expanded Derivation of the Threshold Structure of the Polytomous Rasch Model That Dispels Any “Threshold Disorder Controversy.” Educ Psychol Meas. 2013;73(1):78–124.CrossRef Andrich D. An Expanded Derivation of the Threshold Structure of the Polytomous Rasch Model That Dispels Any “Threshold Disorder Controversy.” Educ Psychol Meas. 2013;73(1):78–124.CrossRef
27.
go back to reference Andrich D. The Legacies of R. A. Fisher and K. Pearson in the Application of the Polytomous Rasch Model for Assessing the Empirical Ordering of Categories. Educ Psychol Meas. 2013;73(4):553–80.CrossRef Andrich D. The Legacies of R. A. Fisher and K. Pearson in the Application of the Polytomous Rasch Model for Assessing the Empirical Ordering of Categories. Educ Psychol Meas. 2013;73(4):553–80.CrossRef
28.
go back to reference Hagell P. Measuring activities of daily living in Parkinson’s disease: On a road to nowhere and back again? Meas. 2019;132:109–24.CrossRef Hagell P. Measuring activities of daily living in Parkinson’s disease: On a road to nowhere and back again? Meas. 2019;132:109–24.CrossRef
29.
go back to reference Hagquist C, Andrich D. Recent advances in analysis of differential item functioning in health research using the Rasch model. Health Qual Life Outcomes. 2017;15(1):181.CrossRef Hagquist C, Andrich D. Recent advances in analysis of differential item functioning in health research using the Rasch model. Health Qual Life Outcomes. 2017;15(1):181.CrossRef
30.
go back to reference Hagquist C. Explaining differential item functioning focusing on the crucial role of external information - an example from the measurement of adolescent mental health. BMC Med Res Methodol. 2019;19(1):185.CrossRef Hagquist C. Explaining differential item functioning focusing on the crucial role of external information - an example from the measurement of adolescent mental health. BMC Med Res Methodol. 2019;19(1):185.CrossRef
31.
go back to reference Marais I. Local Dependence. In: Christensen K, editor. Rasch Models in Health. Kreiner S: Mesbah M. John Wiley & Sons, Inc.; 2013. p. 111–30.CrossRef Marais I. Local Dependence. In: Christensen K, editor. Rasch Models in Health. Kreiner S: Mesbah M. John Wiley & Sons, Inc.; 2013. p. 111–30.CrossRef
32.
go back to reference Andrich D. Rasch models for measurement. Beverley Hills, CA: Sage Publications; 1988.CrossRef Andrich D. Rasch models for measurement. Beverley Hills, CA: Sage Publications; 1988.CrossRef
33.
go back to reference De Pablo-Fernandez E, Tur C, Revesz T, Lees AJ, Holton JL, Warner TT. Association of Autonomic Dysfunction With Disease Progression and Survival in Parkinson Disease. JAMA Neurol. 2017;74(8):970–6.CrossRef De Pablo-Fernandez E, Tur C, Revesz T, Lees AJ, Holton JL, Warner TT. Association of Autonomic Dysfunction With Disease Progression and Survival in Parkinson Disease. JAMA Neurol. 2017;74(8):970–6.CrossRef
34.
go back to reference Bostantjopoulou S, Katsarou Z, Danglis I, Karakasis H, Milioni D, Falup-Pecurariu C. Self-reported autonomic symptoms in Parkinson’s disease: properties of the SCOPA-AUT scale. Hippokratia. 2016;20(2):115–20. Bostantjopoulou S, Katsarou Z, Danglis I, Karakasis H, Milioni D, Falup-Pecurariu C. Self-reported autonomic symptoms in Parkinson’s disease: properties of the SCOPA-AUT scale. Hippokratia. 2016;20(2):115–20.
Metadata
Title
Novel insights regarding the measurement properties of the SCOPA-AUT
Authors
Albert Westergren
Klas Wictorin
Oskar Hansson
Peter Hagell
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Neurology / Issue 1/2022
Electronic ISSN: 1471-2377
DOI
https://doi.org/10.1186/s12883-022-03008-2

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