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Open Access 01-12-2023 | Parkinson's Disease | Matters Arising

Hypoxia treatment of Parkinson’s disease may disrupt the circadian system

Authors: Olivier Coste, Yvan Touitou

Published in: BMC Neurology | Issue 1/2023

Excerpt

We have read the recent article by Janssen Daalen et al. titled "Multiple N-of-1trials to investigate hypoxia therapy in Parkinson’s disease: study rationale and protocol" [1] with great interest and would like to comment on it. The rationale for using hypoxia therapy in Parkinson’s disease (PD) and a detailed study protocol are presented in this paper. …

Janssen Daalen JM, Meinders MJ, Giardina F, Roes KCB, Stunnenberg BC, Mathur S, Ainslie PN, Thijssen DHJ, Bloem BR. Multiple N-of-1trials to investigate hypoxia therapy in Parkinson’s disease: study rationale and protocol. BMC Neurol. 2022;22:262. https://doi.org/10.1186/S12883-022-02770-7.CrossRefPubMedPubMedCentral

Navarrete-Opazo A, Mitchell GS. Therapeutic potential of intermittent hypoxia: a matter of dose. Am J Physiol Regul Integr Comp Physiol. 2014;307(10):R1181–97.

Burtscher J, Mallet RT, Burtscher M, Millet GP. Hypoxia and brain aging: neurodegeneration or neuroprotection. Aging Res Rev. 2021;68:101343. https://doi.org/10.1016/j.arr.2021.101343.

Leng Y, Musiek ES, Hu K, Cappuccio FP, Yaffe K. Association between circadian rhythms and neurodegenerative diseases (review). Lancet Neurol. 2019;18(3):307–18.CrossRefPubMedPubMedCentral

Coste O, Beaumont M, Van Beers P, Batéjat D, Charbuy H, Touitou Y. Hypoxic depression of melatonin secretion after simulated long lasting flights in man. J Pineal Res. 2004;37(1):1–10.CrossRefPubMed

Coste O, Beaumont M, Van Beers P, Batéjat D, Touitou Y. Prolonged mild hypoxia modifies human circadian core body temperature and may be associated with sleep disturbances. Chronobiol Int. 2004;21(3):419–33.CrossRefPubMed

Coste O, Van Beers P, Bogdan A, Charbuy H, Touitou Y. Hypoxic alterations of cortisol circadian rhythm in man after simulation of a long duration flight. Steroids. 2005;70:803–10.CrossRefPubMed

Coste O, Van Beers P, Touitou Y. Impact of hypobaric hypoxia in pressurized cabins of simulated long-distance flights on the 24 h patterns of biological variables, fatigue and clinical status. Chronobiol Int. 2007;24(6):1139–57.CrossRefPubMed

Coste O, Chaumet G, Van Beers P, Touitou Y. Hypobaric impact on clinical tolerance and 24-h patterns in iron metabolism markers and plasma proteins in men. Chronobiol Int. 2011;28(5):434–45.CrossRefPubMed

10.

Coste O, Van Beers P, Touitou Y. Hypoxia-induced changes in recovery sleep, core body temperature, urinary 6-sulfatoxymelatonin and free cortisol after a simulated long-duration flight. J Sleep Res. 2009;18(4):454–65.CrossRefPubMed

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Furian M, Bitos K, Hartmann SE, Muralt L, Lichtbau M, Bader PR, Rawling JM, Ulrich S, Poulin MJ, Bloch KE. Acute high altitude exposure, acclimatization and re-exposure on nocturnal breathing. Front Physiol 2022;13:965021. https://doi.org/10.3389/fphys.2022.965021.

12.

Adamovich Y, Dandavate V, Asher G. Circadian clocks' interactions with oxygen sensing and signalling (review). Acta Physiol (Oxf). 2022;234(2):e13770. https://doi.org/10.1111/apha.13770. Epub 2022 Jan 19.

13.

Reinberg A, Touitou Y, Lewy H, Mechkouri M. Habitual moderate alcohol consumption desynchronizes circadian physiologic rhythms and affects reaction-time performance. Chronobiol Int. 2010;27(9–10):1930–42.CrossRefPubMed

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Dispersyn G, Pain L, Challet E, Touitou Y. General anesthetics effects on circadian temporal structure: an update. Chronobiol Int. 2008;25(6):835–50.CrossRefPubMed

15.

Gadacha W, Ben-Attia M, Bonnefont-Rousselot D, Aouani E, Ghanem-Boughanmi N, Touitou Y. Resveratrol opposite effects on rat tissue lipoperoxidation: pro-oxidant during day-time and antioxidant at night. Redox Rep. 2009;14(4):154–8.CrossRefPubMed

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Touitou Y, Point S. Effects and mechanisms of action of light-emitting diodes on the human retina and internal clock. Environ Res. 2020;190: 109942.CrossRefPubMed

Title: Hypoxia treatment of Parkinson’s disease may disrupt the circadian system
Authors: Olivier Coste
Yvan Touitou
Publication date: 01-12-2023
Publisher: BioMed Central
Keyword: Parkinson's Disease
Published in: BMC Neurology / Issue 1/2023
Electronic ISSN: 1471-2377
DOI: https://doi.org/10.1186/s12883-023-03270-y

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Correction to: Hypoxia treatment of Parkinson’s disease may disrupt the circadian system