Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
BMC Neurology
Published in: BMC Neurology 1/2022

Open Access 01-12-2022 | Parkinson's Disease | Research

Comparison of erector spinae fatigability between female patients with Parkinson’s disease and healthy individuals: a cross sectional pilot study

Authors: Yukihide Nishimura, Hiroyuki Tsuboi, Ken-Ya Murata, Yuta Minoshima, Hideyuki Sato, Yuichi Umezu, Fumihiro Tajima

Published in: BMC Neurology | Issue 1/2022

Login to get access

Abstract

Background

Postural abnormality is one of the main symptoms of Parkinson’s disease (PD). The erector spinae muscles play an important role in maintaining an upright posture, but the fatigability of the erector spinae in patients with PD is unknown. The purpose of this study was to compare the trunk extension maximum voluntary contraction (MVC) and the fatigability of the erector spinae between female patients with PD and healthy volunteers.

Methods

Th participants of this cross-sectional pilot study comprised 19 patients with PD and nine healthy volunteers matched for sex, age, and physical characteristics as a control group. The MVC of all participants was measured, and after sufficient rest, the Sørensen back endurance test was conducted to the point of exhaustion. The muscle activity of the erector spinae during the Sørensen back endurance test was measured using surface electromyography. The median frequency (MF) slope, which is an index of fatigability, was calculated from the recorded surface muscle activity by means of power spectrum analysis using a Fast Fourier transformation.

Results

Nine of the 19 patients with PD were unable to perform the Sørensen back endurance test, and a lower proportion of the PD group were able to perform it compared with the control group. The MVC of those patients with PD who were able to perform the Sørensen back endurance test was lower than that of the control group, and the time for which the pose could be maintained was shorter. There was no significant difference between the MF slope on the left and right side in the PD group, and it was higher on both sides than in the control group.

Conclusion

This is the first study to demonstrate a reduction of maximum muscle strength and great fatigability of the erector spinae in patients with PD. This discovery strongly underlines the need for paraspinal muscle training from an early stage with the aim of preventing the progression of postural abnormality in patients with PD.
Literature
1.
Campbell GR, Reeve A, Ziabreva I, Polvikoski TM, Taylor RW, Reynolds R, et al. Mitochondrial DNA deletions and depletion within paraspinal muscles. Neuropathol Appl Neurobiol. 2013;39(4):377–89.CrossRef
2.
Galea MP, Hammar I, Nilsson E, Jankowska E. Bilateral postsynaptic actions of pyramidal tract and reticulospinal neurons on feline erector spinae motoneurons. J Neurosci. 2010;30(3):858–69.CrossRef
3.
Ondo WG, Haykal HA. Paraspinal muscle asymmetry in Parkinson's disease. Int J Neurosci. 2014;124(2):93–6.CrossRef
4.
Lavin KM, Sealfon SC, McDonald MN, Roberts BM, Wilk K, Nair VD, et al. Skeletal muscle transcriptional networks linked to type 1 myofiber, grouping in Parkinson’s disease. J Appl Physiol. 2020;128:229–40.CrossRef
5.
Stevens-Lapsley J, Kluger BM, Schenkman M. Quadriceps muscle weakness, activation deficits, and fatigue with Parkinson disease. Neurorehabil Neural Repair. 2012;26:533–41.CrossRef
6.
Cano-de-la-Cuerda R, Pérez-de-Heredia M, Miangolarra-Page JC, Muñoz-Hellín E, Fernández-de-Las-Peñas C. Is there muscular weakness in Parkinson’s disease? Am J Phys Med Rehabili. 2010;89:70–6.CrossRef
7.
Biering-Sørensen F. Physical measurements as risk indicators for low-back trouble over a one-year period. Spine. 1984;9:106–19.CrossRef
8.
Demoulin C, Vanderthommen M, Duysens C, Crielaard JM. Spinal muscle evaluation using the Sorensen test: a critical appraisal of the literature. Joint Bone Spine. 2006;73(1):43–50.CrossRef
9.
Ng JK, Richardson CA. Reliability of electromyographic power spectral analysis of back muscle endurance in healthy subjects. Arch Phys Med Rehabil. 1996;77(3):259–64.CrossRef
10.
Mannion AF, Dumas GA, Stevenson JM, Cooper RG. The influence of muscle fiber size and type distribution on electromyographic measures of back muscle fatigability. Spine. 1998;23(5):576–84.CrossRef
11.
Umezu Y, Kawazu T, Tajima F, Ogata H. Spectral electromyographic fatigue analysis of back muscles in healthy adult women compared with men. Arch Phys Med Rehabil. 1998;79(5):536–8.CrossRef
12.
Tsuboi H, Nishimura Y, Sakata T, Ohko H, Tanina H, Kouda K, et al. Age-related sex differences in erector spinae muscle endurance using surface electromyographic power spectral analysis in healthy humans. Spine J. 2013;13(12):1928–33.CrossRef
13.
Tsuboi H, Nishimura Y, Sakata T, Tanina H, Arakawa H, Nakamura T, et al. Properties of paraspinal muscles in Japanese high school baseball players with terminal-stage lumbar spondylolysis. PM R. 2018;10(2):175–82.CrossRef
14.
Tanina H, Nishimura Y, Tsuboi H, Sakata T, Nakamura T, Murata KY, et al. Fatigue-related differences in erector spinae between prepubertal children and young adults using surface electromyographic power spectral analysis J Back Musculoskelet Rehabil. 2017;30:1–9.
15.
Kankaanpää M, Laaksonen D, Taimela S, Kokko SM, Airaksinen O, Hänninen O. Age, sex, and body mass index as determinants of back and hip extensor fatigue in the isometric Sørensen back endurance test. Arch Phys Med Rehabil. 1998;79(9):1069–75.CrossRef
16.
Villafañe JH, Gobbo M, Peranzoni M, Naik G, Imperio G, Cleland JA, et al. Validity and everyday clinical applicability of lumbar muscle fatigue assessment methods in patients with chronic non-specific low back pain: a systematic review. Disabil Rehabil. 2016;38(19):1859–71.CrossRef
17.
Sasaki T, Yoshimura N, Hashizume H, Yamada H, Oka H, Matsudaira K, et al. MRI-defined paraspinal muscle morphology in Japanese population: the Wakayama spine study. PLoS One. 2017;12(11):e0187765.CrossRef
18.
Kimura H, Kurimura M, Wada M, Kawanami T, Kurita K, Suzuki Y, et al. Female preponderance of Parkinson's disease in Japan. Neuroepidemiology. 2002;21(6):292–6.CrossRef
19.
Park JH, Kim DH, Kwon DY, Choi M, Kim S, Jung JH, et al. Trends in the incidence and prevalence of Parkinson's disease in Korea: a nationwide, population-based study. BMC Geriatr. 2019;19(1):320.CrossRef
20.
Srivanitchapoom P, Hallett M. Camptocormia in Parkinson's disease: definition, epidemiology, pathogenesis and treatment modalities. J Neurol Neurosurg Psychiatry. 2016;87(1):75–85.PubMed
21.
Tinazzi M, Fasano A, Geroin C, Morgante F, Ceravolo R, Rossi S, et al. Pisa syndrome in Parkinson disease: an observational multicenter Italian study. Neurology. 2015;85(20):1769–79.CrossRef
22.
Merletti R. Standards for reporting EMG data. J Electromyogr Kinesiol. 1999;9:3–4.
23.
Holmström E, Moritz U, Andersson M. Trunk muscle strength and back muscle endurance in construction workers with and without low back disorders. Scand J Rehabil Med. 1992;24(1):3–10.PubMed
24.
Moreau CE, Green BN, Johnson CD, Moreau SR. Isometric back extension endurance tests: a review of the literature. J Manip Physiol Ther. 2001;24(2):110–22.CrossRef
25.
Kupa EJ, Roy SH, Kandarian SC, De Luca CJ. Effects of muscle fiber type and size on EMG median frequency and conduction velocity. J Appl Physiol. 1995;79:23–32.CrossRef
26.
Mannion AF, Dumas GA, Cooper RG, Espinosa FJ, Faris MW, Stevenson JM. Muscle fibre size and type distribution in thoracic and lumbar regions of erector spinae in healthy subjects without low back pain: normal values and sex difference. J Anat. 1997;190:505–13.CrossRef
27.
Champagne A, Descarreaux M, Lafond D. Back and hip extensor muscles fatigue in healthy subjects: task-dependency effect of two variants of the Sorensen test. Eur Spine J. 2008;17(12):1721–6.CrossRef
28.
Geroin C, Artusi CA, Gandolfi M, Zanolin E, Ceravolo R, Capecci M. Does the degree of trunk bending predict patient disability, motor impairment, falls, and Back pain in Parkinson's disease? Front Neurol. 2020;11:207.CrossRef
29.
Morton RW, Sonne MW, Farias Zuniga A, Mohammad IYZ, Jones A, McGlory C, et al. Muscle fibre activation is unaffected by load and repetition duration when resistance exercise is performed to task failure. J Physiol. 2019;597(17):4601–13.CrossRef
30.
da Silva RA, Larivière C, Arsenault AB, Nadeau S, Plamondon A. Effect of pelvic stabilization and hip position on trunk extensor activity during back extension exercises on a Roman chair. J Rehabil Med. 2009;41(3):136–42.CrossRef
31.
Bassel-Duby R, Olson EN. Signaling pathways in skeletal muscle remodeling. Annu Rev Biochem. 2006;75:19–37.CrossRef
32.
Asaka M, Usui C, Ohta M, Takai Y, Fukunaga T, Higuchi M. Elderly oarsmen have larger trunk and thigh muscles and greater strength than age-matched untrained men. Eur J Appl Physiol. 2010;108(6):1239–45.CrossRef
Metadata
Title
Comparison of erector spinae fatigability between female patients with Parkinson’s disease and healthy individuals: a cross sectional pilot study
Authors
Yukihide Nishimura
Hiroyuki Tsuboi
Ken-Ya Murata
Yuta Minoshima
Hideyuki Sato
Yuichi Umezu
Fumihiro Tajima
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Neurology / Issue 1/2022
Electronic ISSN: 1471-2377
DOI
https://doi.org/10.1186/s12883-022-02719-w

Other articles of this Issue 1/2022

BMC Neurology 1/2022 Go to the issue

Research

The safety and efficacy of umbilical cord blood mononuclear cells in individuals with spastic cerebral palsy: a randomized double-blind sham-controlled clinical trial

Research

Serum NFL discriminates Parkinson disease from essential tremor and reflect motor and cognition severity

Research

Serum biomarkers of neuroinflammation and blood-brain barrier leakage in amyotrophic lateral sclerosis

Study protocol

Study protocol of transcranial electrical stimulation at alpha frequency applied during rehabilitation: A randomized controlled trial in chronic stroke patients with visuospatial neglect

Research

Characteristics of non-stenotic carotid plaque in embolic stroke of undetermined source compared with cardiogenic embolism: a retrospective cross-sectional observational study

Research article

COVID-19 related outcomes among individuals with neurodegenerative diseases: a cohort analysis in the UK biobank