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01-07-2020 | Parkinson's Disease | Brief Communication

Video analysis of long-term effects of levodopa-carbidopa intestinal gel on gait and posture in advanced Parkinson’s disease

Authors: Margherita Fabbri, Chatkaew Pongmala, Carlo Alberto Artusi, Gabriele Imbalzano, Alberto Romagnolo, Leonardo Lopiano, Maurizio Zibetti

Published in: Neurological Sciences | Issue 7/2020

Abstract

Gait and posture parameters of ten advanced Parkinson’s disease (PD) patients were assessed before and after starting levodopa-carbidopa intestinal gel (LCIG) treatment by means of both objective video analysis and clinical assessment. After 3 years of treatment, gait and posture remained stable. A slower gait velocity at baseline significantly correlates with a higher axial and motor severity at follow-up. This pilot study suggests that validated video analysis software may support the clinical assessment of axial signs in PD patients who are candidates for device-aided therapies.

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Title: Video analysis of long-term effects of levodopa-carbidopa intestinal gel on gait and posture in advanced Parkinson’s disease
Authors: Margherita Fabbri
Chatkaew Pongmala
Carlo Alberto Artusi
Gabriele Imbalzano
Alberto Romagnolo
Leonardo Lopiano
Maurizio Zibetti
Publication date: 01-07-2020
Publisher: Springer International Publishing
Keywords: Parkinson's Disease
Carbidopa
Levodopa
Published in: Neurological Sciences / Issue 7/2020
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-020-04319-3

At a glance: The STEP trials

Springer Medicine

Video analysis of long-term effects of levodopa-carbidopa intestinal gel on gait and posture in advanced Parkinson’s disease

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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