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Osteoporosis International

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01-06-2011 | Original Article

Parity and risk of hip fracture in postmenopausal women

Authors: M. Kauppi, M. Heliövaara, O. Impivaara, P. Knekt, A. Jula

Published in: Osteoporosis International | Issue 6/2011

Abstract

Summary

Hip fracture risk was assessed according to parity among postmenopausal women. Compared with nulliparous women, the fracture risk was lower in women with three or more births.

Introduction

Parity was assessed for long-term prediction of hip fracture in postmenopausal women.

Methods

Postmenopausal women (n = 2,028) aged 45 or over with no history of hip fracture were studied. From 1978 to 1980, all of them had participated in a comprehensive health survey based on a nationally representative population sample. Emerging cases of hip fracture were identified from the National Hospital Discharge Register during a follow-up period extending up to 17 years.

Results

The risk of hip fracture was lower among parous women compared with nulliparous women. The model adjusted for age showed a significant inverse association between parity as a continuous variable and the risk of hip fracture [RR = 0.74; 95% confidence interval (CI), 0.61–0.90] per an increment of one standard deviation (2.4 births). Adjusted for age, menopausal age, level of education, body mass index, vitamin D status, alcohol consumption, smoking history, leisure time physical activity, and self-rated health, the relative risk was 0.50 (95% CI, 0.32–0.79) for women with three or more births and 0.85 (95% CI, 0.55–1.32) for women with one to two births as compared with nulliparous women.

Conclusion

Parity, three or more births in particular, predicts a lowered risk of hip fracture in the long run.

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Title: Parity and risk of hip fracture in postmenopausal women
Authors: M. Kauppi
M. Heliövaara
O. Impivaara
P. Knekt
A. Jula
Publication date: 01-06-2011
Publisher: Springer-Verlag
Published in: Osteoporosis International / Issue 6/2011
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI: https://doi.org/10.1007/s00198-010-1392-1

At a glance: The STEP trials

Springer Medicine

Parity and risk of hip fracture in postmenopausal women

Abstract

Summary

Introduction

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Summary

Introduction

Methods

Results

Conclusion

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