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European Journal of Clinical Microbiology & Infectious Diseases

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01-10-2007 | Concise Article

Panton-Valentine leukocidin genes and staphylococcal chromosomal cassette mec types amongst Finnish community-acquired methicillin-resistant Staphylococcus aureus strains, 1997–1999

Authors: M. Kardén-Lilja, S. Ibrahem, J. Vuopio-Varkila, S. Salmenlinna, O. Lyytikäinen, L. Siira, A. Virolainen

Published in: European Journal of Clinical Microbiology & Infectious Diseases | Issue 10/2007

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) strains from Finland covering years 1997–1999 were studied for the presence of Panton-Valentine leukocidin (PVL) gene loci, and the clinically well-defined community-acquired MRSA (CA-MRSA) strains (n = 108) also for staphylococcal chromosomal cassette mec (SCCmec) and multilocus sequence types (MLST). Only a minority (12%) of the CA-MRSA strains contained the PVL gene loci and possessed genotypes formerly described as typical to CA-MRSA strains. The majority of these strains were heterogenous by MLST and pulsed-field gel electrophoresis (PFGE) analysis but, however, harboured the SCCmec cassette type IV. In conclusion, it seems doubtful to consider only molecular characteristics such as the presence of PVL genes as definite markers for CA-MRSA strains.

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Title: Panton-Valentine leukocidin genes and staphylococcal chromosomal cassette mec types amongst Finnish community-acquired methicillin-resistant Staphylococcus aureus strains, 1997–1999
Authors: M. Kardén-Lilja
S. Ibrahem
J. Vuopio-Varkila
S. Salmenlinna
O. Lyytikäinen
L. Siira
A. Virolainen
Publication date: 01-10-2007
Publisher: Springer-Verlag
Published in: European Journal of Clinical Microbiology & Infectious Diseases / Issue 10/2007
Print ISSN: 0934-9723
Electronic ISSN: 1435-4373
DOI: https://doi.org/10.1007/s10096-007-0334-0

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