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Published in: BMC Surgery 1/2014

Open Access 01-12-2014 | Case report

Pancytopenia in a surgical patient, a rare presentation of hyperthyroidism

Authors: Prabhat Jha, Yogendra Prasad Singh, Bikal Ghimire, Binit Kumar Jha

Published in: BMC Surgery | Issue 1/2014

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Abstract

Background

Pancytopenia is a rare complication of hyperthyroidism. Various mechanisms have been described such as immunological, bone marrow suppression. The possibility of hyperthyroidism should be considered in patients with unexplained pancytopenia. There are many case reports showing the association between hyperthyroidism and pancytopenia. All of these reports show association between Graves disease and pancytopenia but our case shows association between Multinodular goitre and pancytopenia. Besides it is uncommon to find such association in a surgical patient.

Case presentation

This case report describes a 62 yr old hindu female with splenic injury and pancytopenia. On further investigations the patient was found to have hyperthyroidism.

Conclusion

Though the definite mechanism regarding the association of pancytopenia with hyperthyroidism isn’t clear, various cases have been described in the literature. This case shows the diagnostic dilemma that can occur in patients with pancytopenia. Any patient with unexplained pancytopenia should undergo thyroid function tests to rule out hyperthyroidism.
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Metadata
Title
Pancytopenia in a surgical patient, a rare presentation of hyperthyroidism
Authors
Prabhat Jha
Yogendra Prasad Singh
Bikal Ghimire
Binit Kumar Jha
Publication date
01-12-2014
Publisher
BioMed Central
Published in
BMC Surgery / Issue 1/2014
Electronic ISSN: 1471-2482
DOI
https://doi.org/10.1186/1471-2482-14-108

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