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23-12-2022 | Pancreatoduodenostomy | Original Article

Vascular resection for distal cholangiocarcinoma

Authors: Ryusei Yamamoto, Teiichi Sugiura, Ryo Ashida, Katsuhisa Ohgi, Mihoko Yamada, Shimpei Otsuka, Takeshi Aramaki, Koiku Asakura, Katsuhiko Uesaka

Published in: Surgery Today | Issue 8/2023

Abstract

Purpose

Vascular resection (VR) is extended surgery to attain a negative radial margin (RM) for distal cholangiocarcinoma (DCC). The present study explored the significance of VR for DCC, focusing on VR, RM, and findings suggestive of vascular invasion on multidetector-row computed tomography (MDCT).

Methods

Patients with DCC who underwent resection between 2002 and 2019 were reviewed.

Results

Among 230 patients, 25 received VR. The overall survival (OS) in the VR group was significantly worse than in the non-VR group (16.7% vs. 50.7% at 5 years, P < 0.001). Patients who underwent VR with a negative RM failed to show a better OS than those who did not undergo VR with a positive RM (19.7% vs. 35.7% at 5 years, P = 0.178). Of the 30 patients who were suspected of having vascular invasion on MDCT, 11 did not receive VR because the vessels were freed from the tumor; these patients had a significantly better OS (57.9% at 5 years) than those who underwent VR.

Conclusions

VR for DCC was associated with a poor prognosis, even if a negative RM was obtained. VR is not necessary for DCC when the vessels are detachable from the tumor.

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Title: Vascular resection for distal cholangiocarcinoma
Authors: Ryusei Yamamoto
Teiichi Sugiura
Ryo Ashida
Katsuhisa Ohgi
Mihoko Yamada
Shimpei Otsuka
Takeshi Aramaki
Koiku Asakura
Katsuhiko Uesaka
Publication date: 23-12-2022
Publisher: Springer Nature Singapore
Keywords: Pancreatoduodenostomy
Pancreatoduodenostomy
Cholangiocarcinoma
Cholangiocarcinoma
Published in: Surgery Today / Issue 8/2023
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI: https://doi.org/10.1007/s00595-022-02634-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Vascular resection for distal cholangiocarcinoma

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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