Published in:
Open Access
01-12-2014 | Case report
Paliperidone extended release for the treatment of pediatric and adolescent patients with Tourette's disorder
Authors:
Kazuhiko Yamamuro, Manabu Makinodan, Toyosaku Ota, Junzo Iida, Toshifumi Kishimoto
Published in:
Annals of General Psychiatry
|
Issue 1/2014
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Abstract
Objective
A subgroup of patients with Tourette's disorder (TD) has symptoms refractory to haloperidol, a standard therapeutic drug for TD.
Methods
We report on three cases of pediatric and adolescent patients who were treated with paliperidone extended release.
Results
In two cases, TD symptoms were remarkably improved by switching from haloperidol to paliperidone extended release, and in another case, paliperidone extended release showed significant efficacy in treating TD symptoms as the first-line drug. In all cases, no significant adverse side effects were detected.
Conclusion
Paliperidone extended release may be a strong candidate for the treatment of pediatric and adolescent patients with TD.