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Published in: Annals of General Psychiatry 1/2014

Open Access 01-12-2014 | Case report

Paliperidone extended release for the treatment of pediatric and adolescent patients with Tourette's disorder

Authors: Kazuhiko Yamamuro, Manabu Makinodan, Toyosaku Ota, Junzo Iida, Toshifumi Kishimoto

Published in: Annals of General Psychiatry | Issue 1/2014

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Abstract

Objective

A subgroup of patients with Tourette's disorder (TD) has symptoms refractory to haloperidol, a standard therapeutic drug for TD.

Methods

We report on three cases of pediatric and adolescent patients who were treated with paliperidone extended release.

Results

In two cases, TD symptoms were remarkably improved by switching from haloperidol to paliperidone extended release, and in another case, paliperidone extended release showed significant efficacy in treating TD symptoms as the first-line drug. In all cases, no significant adverse side effects were detected.

Conclusion

Paliperidone extended release may be a strong candidate for the treatment of pediatric and adolescent patients with TD.
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Metadata
Title
Paliperidone extended release for the treatment of pediatric and adolescent patients with Tourette's disorder
Authors
Kazuhiko Yamamuro
Manabu Makinodan
Toyosaku Ota
Junzo Iida
Toshifumi Kishimoto
Publication date
01-12-2014
Publisher
BioMed Central
Published in
Annals of General Psychiatry / Issue 1/2014
Electronic ISSN: 1744-859X
DOI
https://doi.org/10.1186/1744-859X-13-13

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