P055. Prevalence of migraine in subclinical hypothyroidism: a case-control study

Excerpt

The existence of an association between migraine and thyroid diseases is still a matter of debate. Epidemiological studies have shown a potential association between plasma TSH concentrations and migraine but results are contradictory. Subclinical hypothyroidism (SCH) is a common clinical entity defined biochemically as a normal serum free thyroxine (fT4) concentration in the presence of an elevated serum thyroid-stimulating hormone (TSH) concentration. In population-based studies, the prevalence of SCH ranges from 4 to 15 percent, the diagnosis being more common in women and in old age. Prospective data have shown that SCH is a risk factor for coronary heart disease, heart failure, and cardiovascular mortality, probably related to a mechanism of endothelial dysfunction and low grade chronic inflammation. A recent study suggested an increased prevalence of subclinical hypothyroidism in childhood migraine. …