Published in:
Open Access
01-06-2012 | Poster presentation
P02.97. Lipoic acid supplementation induces a transient stress response and improves episodic memory and cholesterol efflux in humans
Authors:
D Keith, J Butler, B Bemer, J Mogle, J Monette, J Hair, J Heinecke, M Sliwinski, T Hagen
Published in:
BMC Complementary Medicine and Therapies
|
Special Issue 1/2012
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Excerpt
Lipoic acid (LA) shows promise as a beneficial micronutrient in improving health, particularly in the elderly. Clinical and in vitro reports show that LA induces endogenous antioxidants and acts as an anti-inflammatory agent. LA also increases nerve conductance, improves diabetes-induced polyneuropathies, and remediates the age-associated cognitive decline in canines. Furthermore, LA significantly improves hypertriglyceridemia and glucose handling. From our pre-clinical research we have found that LA primarily influences three areas of health: cognition, stress response, and lipids. This study examines the effects of LA on human subjects in components of each of the three aforementioned areas of health. …