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Published in: Pediatric Rheumatology 1/2013

Open Access 01-11-2013 | Meeting abstract

P01-050 – Anakinra in systemic JIA: single center experience

Authors: M Pardeo, A Insalaco, C Bracaglia, R Nicolai, AE Tozzi, G Prencipe, F De Benedetti

Published in: Pediatric Rheumatology | Special Issue 1/2013

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Excerpt

Systemic juvenile idiopathic arthritis (sJIA) accounts for 10-20% of all patients with JIA. The clinical features include fever, evanescent rash, arthralgia and arthritis, myalgia, lymphadenopathy, hepatomegaly, splenomegaly and serositis. Interleukin 1 (IL-1) has been shown to be a major mediator of the inflammatory cascade that underlies sJIA (1). Treatment with anakinra, IL-1 receptor antagonist has been reported to be effective in a subset of patients with sJIA (2). …
Metadata
Title
P01-050 – Anakinra in systemic JIA: single center experience
Authors
M Pardeo
A Insalaco
C Bracaglia
R Nicolai
AE Tozzi
G Prencipe
F De Benedetti
Publication date
01-11-2013
Publisher
BioMed Central
Published in
Pediatric Rheumatology / Issue Special Issue 1/2013
Electronic ISSN: 1546-0096
DOI
https://doi.org/10.1186/1546-0096-11-S1-A53

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