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01-06-2014 | Review

Overcoming short gaps in peripheral nerve repair: conduits and human acellular nerve allograft

Authors: Jonathan Isaacs, Timothy Browne

Published in: HAND | Issue 2/2014

Abstract

Nerve conduits and acellular nerve allograft offer efficient and convenient tools for overcoming unexpected gaps during nerve repair. Both techniques offer guidance for migrating Schwann cells and axonal regeneration though utilizing very different scaffolds. The substantially greater amount of animal and clinical data published on nerve conduits is marked by wide discrepancies in results that may be partly explained by a still poorly defined critical repair gap and diameter size. The available information on acellular allografts appears more consistently positive though this tool is also hampered by a longer but also limited critical length. This article reviews the current relative literature and examines pertinent parameters for application of both acellular allograft and nerve conduits in overcoming short nerve gaps.

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Title: Overcoming short gaps in peripheral nerve repair: conduits and human acellular nerve allograft
Authors: Jonathan Isaacs
Timothy Browne
Publication date: 01-06-2014
Publisher: Springer US
Published in: HAND / Issue 2/2014
Print ISSN: 1558-9447
Electronic ISSN: 1558-9455
DOI: https://doi.org/10.1007/s11552-014-9601-6

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Springer Medicine

Overcoming short gaps in peripheral nerve repair: conduits and human acellular nerve allograft

Abstract

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Springer Medicine

Abstract

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