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01-12-2024 | Overactive Bladder | Original Article

Overactive bladder negatively affects erectile function and promotes premature ejaculation: findings from large representative population-level study

Authors: Mikolaj Przydacz, Nadir Osman, Sabrina De Cillis, Cyrille Guillot-Tantay, Francois Herve, Tanja Hüsch, Ester Illiano, Antonio Tienza Fernandez, Manuela Tutolo, Luis Vale, Mehmet Gokhan Culha, Fabiana Cancrini, Steeve Doizi, Paolo Geretto, Nicholas Raison, Howard B. Goldman, Piotr Chlosta, Veronique Phe

Published in: World Journal of Urology | Issue 1/2024

Abstract

Purpose

The effect of overactive bladder (OAB) on sexual health has been evaluated extensively for women but much less for men. Therefore, the aim of this study was to evaluate the relationship between OAB and men’s sexual activity and the effect of OAB on erectile dysfunction (ED) and premature ejaculation (PE) in a large representative cohort of men at the population level.

Methods

This study was based on computer-assisted web interviews that used validated questionnaires. The most recent census and the sample size estimation calculations were employed to produce a population-representative pool.

Results

The study included 3001 men, representative of the population in terms of age and place of residence. The frequency of sexual intercourse was higher for respondents without OAB symptoms compared with persons who had OAB (p = 0.001), but there was no association between OAB symptoms and number of sexual partners (p = 0.754). Regression models did not confirm the effect of OAB on sexual activity (odds ratio 0.993, CI 0.974–1.013, p = 0.511). Both ED and PE were more prevalent in respondents with OAB symptoms compared with persons who lacked those symptoms (p < 0.001). Importantly, the effect of OAB on ED or PE was independent of age, comorbidities, and lifestyle habits (regression coefficients of 0.13 and 0.158 for ED and PE, respectively).

Conclusion

Overactive bladder did not significantly affect men’s sexual activity, but it significantly correlated with ED and PE. Our results suggest a need in daily clinical practice to screen for OAB symptoms for persons who report ED or PE.

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Title: Overactive bladder negatively affects erectile function and promotes premature ejaculation: findings from large representative population-level study
Authors: Mikolaj Przydacz
Nadir Osman
Sabrina De Cillis
Cyrille Guillot-Tantay
Francois Herve
Tanja Hüsch
Ester Illiano
Antonio Tienza Fernandez
Manuela Tutolo
Luis Vale
Mehmet Gokhan Culha
Fabiana Cancrini
Steeve Doizi
Paolo Geretto
Nicholas Raison
Howard B. Goldman
Piotr Chlosta
Veronique Phe
Publication date: 01-12-2024
Publisher: Springer Berlin Heidelberg
Keywords: Overactive Bladder
Premature Ejaculation
Premature Ejaculation
Erectile Dysfunction
Published in: World Journal of Urology / Issue 1/2024
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI: https://doi.org/10.1007/s00345-024-04841-5

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Overactive bladder negatively affects erectile function and promotes premature ejaculation: findings from large representative population-level study

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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