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Journal of Ovarian Research

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Open Access 01-12-2014 | Research

Ovarian tissue cryopreservation followed by controlled ovarian stimulation and pick-up of mature oocytes does not impair the number or quality of retrieved oocytes

Authors: Marie-Madeleine Dolmans, Maria-Laura Marotta, Céline Pirard, Jacques Donnez, Olivier Donnez

Published in: Journal of Ovarian Research | Issue 1/2014

Abstract

Background

The objective of this study was to evaluate the feasibility of fertility preservation in cancer patients by combined bilateral ovarian cortex cryopreservation and embryo freezing.

Methods

This was a cohort-controlled study in a university hospital center. Sixteen patients with a recent cancer diagnosis were included in the study. They all consented to fertility preservation by a combined technique: ovarian tissue cryopreservation (OTC) followed by ovarian stimulation for in vitro fertilization (IVF) and embryo freezing. The control group included 100 women of the same age undergoing IVF for male factor infertility.

Results

The mean number of metaphase II oocytes was 8.3 per patient (±7.7) and was not statistically different from the control group (8.1 ± 5.6). The mean number of good quality embryos obtained was not statistically different in the 2 groups (4.2 versus 4.4).

Conclusion

OTC before embryo freezing does not impair the number or quality of cryopreserved embryos, but increases fertility preservation potential.

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Title: Ovarian tissue cryopreservation followed by controlled ovarian stimulation and pick-up of mature oocytes does not impair the number or quality of retrieved oocytes
Authors: Marie-Madeleine Dolmans
Maria-Laura Marotta
Céline Pirard
Jacques Donnez
Olivier Donnez
Publication date: 01-12-2014
Publisher: BioMed Central
Published in: Journal of Ovarian Research / Issue 1/2014
Electronic ISSN: 1757-2215
DOI: https://doi.org/10.1186/s13048-014-0080-8

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Ovarian tissue cryopreservation followed by controlled ovarian stimulation and pick-up of mature oocytes does not impair the number or quality of retrieved oocytes

Abstract

Background

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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