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Drug Safety
Published in: Drug Safety 8/2009

01-08-2009 | Editorial

Outliers and Patients with Adverse Drug Reactions

Author: Professor I. Ralph Edwards

Published in: Drug Safety | Issue 8/2009

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Excerpt

Professor David Finney is arguably the initiator of global pharmacovigilance, and, in his 90th year, he can still provoke us to thought! A statistician by training, he has recently criticized the WHO for their removal of outliers[1] in producing normative calibration curves (for thromboplastin time). …
Literature
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2.
Kelly WN, Arellano FM, Barnes J, et al. Guidelines for submitting adverse event reports for publication. Drug Saf 2007; 30(5): 367–73PubMedCrossRef
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Aronson J. Unity from diversity: the evidential use of anecdotal reports of adverse drug reactions and interactions. J Eval Clin Pract 2005; 11: 195–208PubMedCrossRef
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Hauben M, Aronson J. Gold standards in pharmacovigilance: the use of definitive anecdotal reports of adverse drug reactions as pure gold and high grade ore. Drug Saf 2007; 30(8): 645–55PubMedCrossRef
Metadata
Title
Outliers and Patients with Adverse Drug Reactions
Author
Professor I. Ralph Edwards
Publication date
01-08-2009
Publisher
Springer International Publishing
Published in
Drug Safety / Issue 8/2009
Print ISSN: 0114-5916
Electronic ISSN: 1179-1942
DOI
https://doi.org/10.2165/00002018-200932080-00001

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