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Published in: Journal of Orthopaedic Surgery and Research 1/2024

Open Access 01-12-2024 | Osteochondrosis Dissecans | Correspondence

Bilateral juvenile osteochondrosis dissecans in monozygotic twins: a case report

Authors: Luca Bausch, Monika Probst, Lorenz Fritsch, Julian Mehl, Sebastian Siebenlist, Lukas Willinger

Published in: Journal of Orthopaedic Surgery and Research | Issue 1/2024

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Abstract

Introduction

The etiology of osteochondrosis dissecans (OCD), a chondropathy associated with detachment of the subchondral bone and the overlaying cartilage, is not yet fully understood. While repetitive physical exercise-related stress is usually assumed to be the main risk factor for the occurrence of OCD, genetic predisposition could have an underestimated influence on the development of the disease.

Case report

We report a case of monozygotic twins with almost identical stages of bilateral osteochondrosis dissecans of the knee joint. In both patients, initially, a unilateral lesion occurred; despite restricted physical exercise, in the further course of the disease a lesion also developed on the contralateral side. While the lesion found most recently demonstrated an ongoing healing process at a 6-month follow-up, the other three lesions showed a natural course of healing under conservative treatment with significant clinical as well as radiological improvements after one year and complete consolidation in magnetic resonance imaging (MRI) after 2 years.

Conclusion

There could be a genetic component to the development of OCD, although this has not yet been proven. Based on a two-year MRI follow-up, we were able to show the self-limiting characteristics of juvenile osteochondrosis dissecans.
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Metadata
Title
Bilateral juvenile osteochondrosis dissecans in monozygotic twins: a case report
Authors
Luca Bausch
Monika Probst
Lorenz Fritsch
Julian Mehl
Sebastian Siebenlist
Lukas Willinger
Publication date
01-12-2024
Publisher
BioMed Central
Published in
Journal of Orthopaedic Surgery and Research / Issue 1/2024
Electronic ISSN: 1749-799X
DOI
https://doi.org/10.1186/s13018-024-04683-2

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