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Knee Surgery, Sports Traumatology, Arthroscopy
Published in: Knee Surgery, Sports Traumatology, Arthroscopy 10/2023

Open Access 25-04-2023 | Osteoarthrosis | KNEE

Increased complications rates and inferior patient reported outcomes following total knee arthroplasty due to post-traumatic osteoarthritis with previous fracture treatment: a systematic review

Authors: Ioannis Syrikas, Cecilia Engbäck, Georgios Tsikandylakis, Ioannis Karikis, Neel Desai

Published in: Knee Surgery, Sports Traumatology, Arthroscopy | Issue 10/2023

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Abstract

Purpose

This study aims to present the existing literature relating to patient-reported outcome measures (PROMs) and complications in patients undergoing total knee arthroplasty (TKA) due to posttraumatic osteoarthritis (PTOA) with prior fracture treatment around the knee compared with patients who underwent TKA because of primary osteoarthritis (OA).

Methods

A systematic review was undertaken and synthesised in accordance with the PRISMA guidelines by searching existing literature in the following databases: PubMed, Scopus, Cochrane Library and EMBASE. A search string according to the PECO was used. After analysing 2781 studies, 18 studies (5729 PTOA patients/149,843 OA patients) were included for a final review. An analysis revealed that 12 (67%) were retrospective cohort studies, four (22%) were register studies and the remaining two (11%) were prospective cohort studies. The mean Critical Appraisal Skills Programme (CASP) score was 23.6 out of 28, signifying studies of moderate quality.

Results

The most frequently reported outcome measure were postoperative complications, reported in all eighteen studies. Intraoperative complications were reported in ten (4165 PTOA/124.511 OA) and patient-reported outcome measures (PROMs) in six studies (210 PTOA/2768 OA). A total of nine different PROMs were evaluated. As far as PROMs were concerned, the scores were inferior for PTOA but did not differ statistically from OA, except for one study, which favoured the OA group. Across all studies, postoperative complications were higher in the PTOA group, reporting infections as the most common complication. Furthermore, a higher revision rate was reported in the PTOA group.

Conclusion

PROM analysis suggests that both patient groups benefit from a TKA in terms of functional outcome and pain relief, however, patient-reported outcomes could be inferior for PTOA patients. There is consistent evidence for increased complication rates following PTOA TKA. Patients undergoing TKA due to PTOA after fracture treatment should be informed about the risk for inferior results and refrain from comparing their knee function to patients with TKA after OA. Surgeons should be aware of the challenges that PTOA TKA poses.

Level of evidence

Level III.
Appendix
Available only for authorised users
Literature
1.
2.
3.
4.
Anderson DDCS, Guilak F, Martin JA, Oegema TR, Olson SA, Buckwalter JA (2011) Post-traumatic osteoarthritis: improved understanding and opportunities for early intervention. J Orthop Res 29:802–809PubMedPubMedCentralCrossRef
5.
Aurich M, Koenig V, Hofmann G (2018) Comminuted intraarticular fractures of the tibial plateau lead to posttraumatic osteoarthritis of the knee: current treatment review. Asian J Surg 41:99–105PubMedCrossRef
6.
Bergen MA, Ryan SP, Hong CS, Bolognesi MP, Seyler TM (2019) Conversion total knee arthroplasty: a distinct surgical procedure with increased resource utilization. J Arthroplasty 34:S114-s120PubMedCrossRef
7.
Brown TD, Johnston RC, Saltzman CL, Marsh JL, Buckwalter JA (2006) Posttraumatic osteoarthritis: a first estimate of incidence, prevalence, and burden of disease. J Orthop Trauma 20:739–744PubMedCrossRef
8.
Cheng H, Chen BP, Soleas IM, Ferko NC, Cameron CG, Hinoul P (2017) Prolonged operative duration increases risk of surgical site infections: a systematic review. Surg Infect 18:722–735CrossRef
9.
Cheng H, Clymer JW, Po-Han Chen B, Sadeghirad B, Ferko NC, Cameron CG et al (2018) Prolonged operative duration is associated with complications: a systematic review and meta-analysis. J Surg Res 229:134–144PubMedCrossRef
10.
Dexel J, Beyer F, Lützner C, Kleber C, Lützner J (2016) TKA for posttraumatic osteoarthritis is more complex and needs more surgical resources. Orthopedics 39:S36–S40PubMedCrossRef
11.
El-Galaly A, Haldrup S, Pedersen AB, Kappel A, Jensen MU, Nielsen PT (2017) Increased risk of early and medium-term revision after post-fracture total knee arthroplasty. Acta Orthop 88:263–268PubMedPubMedCentralCrossRef
12.
Felson DT, Zhang Y, Hannan MT, Naimark A, Weissman B, Aliabadi P et al (1997) Risk factors for incident radiographic knee osteoarthritis in the elderly: the Framingham study. Arthritis Rheum 40:728–733PubMedCrossRef
13.
Frisch NB, Keating TC, Calkins TE, Culvern CN, Della Valle CJ (2020) Conversion total knee arthroplasty: prior fracture or osteotomy around the knee leads to increased resource utilization. J Arthroplasty 35:3563–3568PubMedCrossRef
14.
Gioe TJ, Novak C, Sinner P, Ma W, Mehle S (2007) Knee arthroplasty in the young patient: survival in a community registry. Clin Orthop Relat Res 464:83–87PubMedCrossRef
15.
Harrysson OL, Robertsson O, Nayfeh JF (2004) Higher cumulative revision rate of knee arthroplasties in younger patients with osteoarthritis. Clin Orthop Relat Res 421:162–168CrossRef
16.
Houdek MT, Shannon SF, Watts CD, Wagner ER, Sems SA, Sierra RJ (2015) Patella fractures prior to total knee arthroplasty: worse outcomes but equivalent survivorship. J Arthroplasty 30:2167–2169PubMedCrossRef
17.
Houdek MT, Watts CD, Shannon SF, Wagner ER, Sems SA, Sierra RJ (2016) Posttraumatic total knee arthroplasty continues to have worse outcome than total knee arthroplasty for osteoarthritis. J Arthroplasty 31:118–123PubMedCrossRef
18.
van Meurs JBJ (2017) Osteoarthritis year in review 2016: genetics, genomics and epigenetics. Osteoarthritis Cartilage 25:181–189PubMedCrossRef
19.
Kester BS, Minhas SV, Vigdorchik JM, Schwarzkopf R (2016) Total knee arthroplasty for posttraumatic osteoarthritis: is it time for a new classification? J Arthroplasty 31:1649–1653PubMedCrossRef
20.
Khoshbin A, Stavrakis A, Sharma A, Woo P, Atrey A, Lee YL et al (2019) Patient-reported outcome measures of total knee arthroplasties for post-traumatic arthritis versus osteoarthritis: a short-term (5- to 10-year) retrospective matched cohort study. J Arthroplasty 34:872–876PubMedCrossRef
21.
Kreitz TM, Deirmengian CA, Penny GS, Maltenfort MG, Deirmengian GK (2017) A current procedural terminology code for “knee conversion” is needed to account for the additional surgical time required compared to total knee arthroplasty. J Arthroplasty 32:20–23PubMedCrossRef
22.
Kurtz S, Ong K, Lau E, Mowat F, Halpern M (2007) Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030. J Bone Joint Surg Am 89:780–785PubMedCrossRef
23.
Liu Y, Zhao XD, Zou C (2020) Lingering risk: a meta-analysis of outcomes following primary total knee arthroplasty for patients with post-traumatic arthritis. Int J Surg 77:163–172PubMedCrossRef
24.
Lizaur-Utrilla A, Collados-Maestre I, Miralles-Muñoz FA, Lopez-Prats FA (2015) Total knee arthroplasty for osteoarthritis secondary to fracture of the tibial plateau. a prospective matched cohort study. J Arthroplasty 30:1328–1332PubMedCrossRef
25.
Lunebourg A, Parratte S, Gay A, Ollivier M, Garcia-Parra K, Argenson JN (2015) Lower function, quality of life, and survival rate after total knee arthroplasty for posttraumatic arthritis than for primary arthritis. Acta Orthop 86:189–194PubMedPubMedCentralCrossRef
26.
Ma L-L, Wang Y-Y, Yang Z-H, Huang D, Weng H, Zeng X-T (2020) Methodological quality (risk of bias) assessment tools for primary and secondary medical studies: what are they and which is better? Mil Med Res 7:7PubMedPubMedCentral
27.
Manrique J, Rasouli MR, Restrepo C, Maltenfort MG, Beri J, Oliver J et al (2018) Total knee arthroplasty in patients with retention of prior hardware material: what is the outcome? Arch Bone Jt Surg 6:23–26PubMedPubMedCentral
28.
Meehan JP, Danielsen B, Kim SH, Jamali AA, White RH (2014) Younger age is associated with a higher risk of early periprosthetic joint infection and aseptic mechanical failure after total knee arthroplasty. J Bone Joint Surg Am 96:529–535PubMedCrossRef
29.
Miozzari HH, Barea C, Hannouche D, Lubbeke A (2021) History of previous surgery is associated with higher risk of revision after primary total knee arthroplasty: a cohort study from the Geneva arthroplasty registry. Acta Orthop 92:709–715PubMedPubMedCentralCrossRef
30.
Naranje S, Lendway L, Mehle S, Gioe TJ (2015) Does operative time affect infection rate in primary total knee arthroplasty? Clin Orthop Relat Res 473:64–69PubMedCrossRef
31.
Njau B, Covin C, Lisasi E, Damian D, Mushi D, Boulle A et al (2019) A systematic review of qualitative evidence on factors enabling and deterring uptake of HIV self-testing in Africa. BMC Public Health 19:1289PubMedPubMedCentralCrossRef
32.
Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD et al (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 372:n71PubMedPubMedCentralCrossRef
33.
Pander P, Fransen BL, Hagemans FJA, Keijser LCM (2021) Functional outcome of total knee arthroplasty following tibial plateau fractures: a systematic review. Arch Orthop Trauma Surg 143(3):1265–1274PubMedCrossRef
34.
Papadopoulos EC, Parvizi J, Lai CH, Lewallen DG (2002) Total knee arthroplasty following prior distal femoral fracture. Knee 9:267–274PubMedCrossRef
35.
Phruetthiphat OA, Zampogna B, Vasta S, Tassanawipas B, Gao Y, Callaghan JJ (2021) TKR after posttraumatic and primary knee osteoarthritis: a comparative study. J Orthop Surg Res 16:173PubMedPubMedCentralCrossRef
36.
Piedade SR, Pinaroli A, Servien E, Neyret P (2013) TKA outcomes after prior bone and soft tissue knee surgery. Knee Surg Sports Traumatol Arthrosc 21:2737–2743PubMedCrossRef
37.
Pinter Z, Jha AJ, McGee A, Paul K, Lee S, Dombrowsky A et al (2020) Outcomes of knee replacement in patients with posttraumatic arthritis due to previous tibial plateau fracture. Eur J Orthop Surg Traumatol 30:323–328PubMedCrossRef
38.
Saleh H, Yu S, Vigdorchik J, Schwarzkopf R (2016) Total knee arthroplasty for treatment of post-traumatic arthritis: systematic review. World J Orthop 7:584–591PubMedPubMedCentralCrossRef
39.
Saleh KJ, Sherman P, Katkin P, Windsor R, Haas S, Laskin R et al (2001) Total knee arthroplasty after open reduction and internal fixation of fractures of the tibial plateau: a minimum five-year follow-up study. J Bone Joint Surg Am 83:1144–1148PubMedCrossRef
40.
Scott CE, Davidson E, MacDonald DJ, White TO, Keating JF (2015) Total knee arthroplasty following tibial plateau fracture: a matched cohort study. Bone Joint J 97:532–538PubMedCrossRef
41.
Skou STRE, Laursen MB (2015) A randomized, controlled trial of total knee replacement. N Engl J Med 373:1597–1606PubMedCrossRef
42.
43.
Stake SN, Gu A, Fassihi SC, Ramamurti P, Bovonratwet P, Thakkar SC et al (2021) Increased revisions in conversion total knee arthroplasty after periarticular open reduction internal fixation compared with primary total knee arthroplasty: a matched cohort analysis. J Arthroplasty 36:3432–3436PubMedCrossRef
44.
Teichtahl AJ, Wang Y, Wluka AE, Cicuttini FM (2008) Obesity and knee osteoarthritis: new insights provided by body composition studies. Obesity 16:232–240PubMedCrossRef
45.
46.
Timothy L, Kahn AS, Schwarzkopf R (2013) Outcomes of total knee arthroplasty in relation to preoperative patient-reported and radiographic measures. Geriatr Orthop Surg Rehabil 4:117–126CrossRef
47.
Vestergaard VBPA, Borbjerg Hare K, MorvilleSchrøder H, Troelsen A (2020) Knee fracture increases TKA risk after initial fracture treatment and throughout life. Clin Orthop Relat Res 478:2036–2044PubMedCrossRef
48.
Weiss NG, Parvizi J, Hanssen AD, Trousdale RT, Lewallen DG (2003) Total knee arthroplasty in post-traumatic arthrosis of the knee. J Arthroplasty 18:23–26PubMedCrossRef
49.
Wood J, Mounasamy V, Wukich D, Sambandam S (2022) Conversion total knee arthroplasty after tibial plateau fixation is associated with lower reimbursement, greater complication rates, and similar opioid use. Cureus 14(5):e25171PubMedPubMedCentral
50.
Metadata
Title
Increased complications rates and inferior patient reported outcomes following total knee arthroplasty due to post-traumatic osteoarthritis with previous fracture treatment: a systematic review
Authors
Ioannis Syrikas
Cecilia Engbäck
Georgios Tsikandylakis
Ioannis Karikis
Neel Desai
Publication date
25-04-2023
Publisher
Springer Berlin Heidelberg
Published in
Knee Surgery, Sports Traumatology, Arthroscopy / Issue 10/2023
Print ISSN: 0942-2056
Electronic ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-023-07407-x

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