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Oral and Maxillofacial Surgery

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01-12-2016 | Original Article

Oral health-related quality of life following third molar surgery with either oral administration or submucosal injection of prednisolone

Authors: Adebayo Aremu Ibikunle, Wasiu Lanre Adeyemo, Akinola Ladipo Ladeinde

Published in: Oral and Maxillofacial Surgery | Issue 4/2016

Abstract

Aim

The aim of this study was to evaluate the changes in oral health-related Quality of Life (QoL) following third molar surgery with either oral administration or submucosal injection of prednisolone.

Patient and methods

Subjects were randomly distributed into three groups of 62 subjects each: Group A consisted of subjects who received 40 mg oral prednisolone; group B received 40 mg submucosal injection of prednisolone, while group C did not receive prednisolone. Preoperative and postoperative quality of life evaluations of all subjects were done using the 14-item Oral Health Impact Profile (OHIP-14) questionnaire. Postoperatively, quality of life evaluation was done on postoperative days 1, 3, and 7. Subjects were categorized as either affected (OHIP score ≤28) or not affected (OHIP score >28). Mean OHIP scores between preoperative and postoperative periods, as well as between the three groups, were compared.

Results

A significant increase in the mean total and subscale scores was found in all the groups postoperatively. This was most marked on the first postoperative day, and it gradually improved throughout the immediate postoperative period. Subjects who received prednisolone experienced a statistically significant better quality of life than those who did not. Subjects who received submucosal injection of prednisolone showed statistically significant less deterioration in QoL than those who received oral prednisolone (P = 0.001).

Conclusion

Administration of prednisolone was significantly associated with less deterioration in quality of life and earlier recovery when compared with subjects who did not receive prednisolone. Submucosal injection of prednisolone 40 mg (which offers a simple, safe, painless, and cost-effective therapeutic option) is an effective therapeutic strategy for improving the quality of life after surgical removal of impacted lower third molars.

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Title: Oral health-related quality of life following third molar surgery with either oral administration or submucosal injection of prednisolone
Authors: Adebayo Aremu Ibikunle
Wasiu Lanre Adeyemo
Akinola Ladipo Ladeinde
Publication date: 01-12-2016
Publisher: Springer Berlin Heidelberg
Published in: Oral and Maxillofacial Surgery / Issue 4/2016
Print ISSN: 1865-1550
Electronic ISSN: 1865-1569
DOI: https://doi.org/10.1007/s10006-016-0571-4

At a glance: The STEP trials

Springer Medicine

Oral health-related quality of life following third molar surgery with either oral administration or submucosal injection of prednisolone

Abstract

Aim

Patient and methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Aim

Patient and methods

Results

Conclusion

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