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01-12-2021 | Sine qua non Clinicopathologic Correlat

Oral Adult Rhabdomyoma

Authors: Augusto César Leal da Silva Leonel, Stefanny Torres dos Santos, Elaine Judite de Amorim Carvalho, Jurema Freire Lisboa de Castro, Oslei Paes de Almeida, Danyel Elias da Cruz Perez

Published in: Head and Neck Pathology | Issue 4/2021

Abstract

This report describes a case of an adult rhabdomyoma (ARM) occurring in the oral cavity. A 47-year-old man was referred for the diagnosis of a painless, well-circumscribed, submucous nodule located on the floor of the mouth, measuring approximately 6.0 cm in length. Computed tomography revealed a well-defined, solid, and hypodense mass. A benign salivary gland or mesenchymal tumor were the main diagnostic hypotheses. Under local anesthesia, the patient underwent surgical excision. Microscopically, the tumor comprised large polygonal well-defined cells with abundant, eosinophilic granular cytoplasm with cross striations. No atypia or mitosis was observed. The cells were positive for muscle-specific actin, desmin, and sarcomeric alpha-actin. Based on these features, a diagnosis of ARM was established. No recurrence was observed after 48 months. Although rare, ARM should be considered in the differential diagnosis of oral submucosal nodules, especially those located on the floor of the mouth.

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Title: Oral Adult Rhabdomyoma
Authors: Augusto César Leal da Silva Leonel
Stefanny Torres dos Santos
Elaine Judite de Amorim Carvalho
Jurema Freire Lisboa de Castro
Oslei Paes de Almeida
Danyel Elias da Cruz Perez
Publication date: 01-12-2021
Publisher: Springer US
Published in: Head and Neck Pathology / Issue 4/2021
Electronic ISSN: 1936-0568
DOI: https://doi.org/10.1007/s12105-021-01371-z

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Oral Adult Rhabdomyoma

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