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Pediatric Rheumatology
Published in: Pediatric Rheumatology 1/2013

Open Access 01-11-2013 | Meeting abstract

OR5-001 – Characterization of tonsil infiltration in PFAPA

Authors: S Chiesa, R Caorsi, F Penco, A Bertoni, S Borghini, A Sementa, A Omenetti, F Bellora, R D'Agostino, A Martini, M Gattorno

Published in: Pediatric Rheumatology | Special Issue 1/2013

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Excerpt

The syndrome of periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) is the most common periodic fever disease in young children. The etiology of this disorder is still unknown. Palatine tonsils are sites where innate immunity leads to onset of the adaptive immunity, mediated by B and T lymphocytes. Three families of pathogen sensors mediate the recognition of microbes: Toll-like receptors (TLRs), NOD-like receptors (NLRs) and RIG-I-like receptors (RLRs). The interplay of these receptors ensures the efficient coordination of innate immune responses. …
Metadata
Title
OR5-001 – Characterization of tonsil infiltration in PFAPA
Authors
S Chiesa
R Caorsi
F Penco
A Bertoni
S Borghini
A Sementa
A Omenetti
F Bellora
R D'Agostino
A Martini
M Gattorno
Publication date
01-11-2013
Publisher
BioMed Central
Published in
Pediatric Rheumatology / Issue Special Issue 1/2013
Electronic ISSN: 1546-0096
DOI
https://doi.org/10.1186/1546-0096-11-S1-A94

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