Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Critical Care
Published in: Critical Care 1/2012

01-02-2012 | Letter

Optimization of oxygen delivery during high-risk surgery: keeping the concept but refining goals for inotrope infusion?

Authors: Emmanuel Futier, Benoit Vallet

Published in: Critical Care | Issue 1/2012

Login to get access

Excerpt

We read with great interest the study by Lobo and colleagues [1] in a recent issue of Critical Care. The authors stated that fluid restriction during optimization of oxygen delivery (DO2) using dobutamine improves patient outcome after major surgery. Previous studies have shown that hemodynamic optimization using either an individualized goal-directed fluid substitution or an inotrope to maximize DO2 reduces postoperative morbidity and hospital length of stay [2]. Although the study by Lobo and colleagues sheds new light on the use of an inotrope during major surgery, we believe that the approach they support raises some unanswered questions. …
Literature
1.
Lobo SM, Ronchi LS, Oliveira NE, Brandao PG, Froes A, Cunrath GS, Mishiyama KG, Netinho JG, Lobo FR: Restrictive strategy of intra-operative fluid maintenance during optimization of oxygen delivery decreases major complications after high-risk surgery. Crit Care 2011, 15: R226. 10.1186/cc10466PubMedCentralCrossRefPubMed
2.
3.
Vallet B, Futier E: Perioperative oxygen therapy and oxygen utilization. Curr Opin Crit Care 2010, 16: 359-364. 10.1097/MCC.0b013e32833bfa3bCrossRefPubMed
4.
Vallet B: Intravascular volume expansion: which surrogate markers could help the clinician to assess improved tissue perfusion? Anesth Analg 2011, 112: 258-259. 10.1213/ANE.0b013e3182066299CrossRefPubMed
5.
Donati A, Loggi S, Preiser JC, Orsetti G, Munch C, Gabbanelli V, Pelaia P, Pietropaoli P: Goal-directed intraoperative therapy reduces morbidity and length of hospital stay in high-risk surgical patients. Chest 2007, 132: 1817-1824. 10.1378/chest.07-0621CrossRefPubMed
6.
Hamilton MA, Cecconi M, Rhodes A: A systematic review and meta-analysis on the use of preemptive hemodynamic intervention to improve postoperative outcomes in moderate and high-risk surgical patients. Anesth Anal 2011, 112: 1392-1402. 10.1213/ANE.0b013e3181eeaae5CrossRef
7.
Gurgel ST, do Nascimento P Jr: Maintaining tissue perfusion in high-risk surgical patients: a systematic review of randomized clinical trials. Anesth Analg 2011, 12: 1384-1391.CrossRef
8.
Shepherd SJ, Pearse RM: Role of central and mixed venous oxygen saturation measurement in perioperative care. Anesthesiology 2009, 111: 649-656. 10.1097/ALN.0b013e3181af59aaCrossRefPubMed
9.
Van Bommel J, Trouwborst A, Schwarte L, Siegemund M, Ince C, Henny ChP: Intestinal and cerebral oxygenation during severe isovolemic hemodilution and subsequent hyperoxic ventilation in a pig model. Anesthesiology 2002, 97: 660-670. 10.1097/00000542-200209000-00021CrossRefPubMed
10.
Shoemaker WC, Appel PL, Kram HB, Waxman K, Lee T: Prospective trial of supranormal values of survivors as therapeutic goals in high risk surgical patients. Chest 1988, 94: 1176-1185. 10.1378/chest.94.6.1176CrossRefPubMed
Metadata
Title
Optimization of oxygen delivery during high-risk surgery: keeping the concept but refining goals for inotrope infusion?
Authors
Emmanuel Futier
Benoit Vallet
Publication date
01-02-2012
Publisher
BioMed Central
Published in
Critical Care / Issue 1/2012
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc11148

Other articles of this Issue 1/2012

Critical Care 1/2012 Go to the issue

Letter

Inflammasome and caspase-1 inhibition caused by Bcl-2 and Bcl-XL may influence cytokine responses of lipopolysaccharide-stimulated peripheral blood mononuclear cells from septic patients

Commentary

Extravascular lung water in acute respiratory distress syndrome: potential clinical value, assumptions and limitations

Research

Clinical utility of biomarkers of endothelial activation in sepsis-a systematic review

Research

Fluid management and risk factors for renal dysfunction in patients with severe sepsis and/or septic shock

Research

Relationship between thyroid function and ICU mortality: a prospective observation study

Research

Alterations in arterial function after high-voltage electrical injury