Skip to main content
Top
Published in: BMC Health Services Research 1/2021

Open Access 01-12-2021 | Research article

Optimisation of maintenance in delivery systems for cytostatic medicines

Authors: María Carmen Carnero, Andrés Gómez

Published in: BMC Health Services Research | Issue 1/2021

Login to get access

Abstract

Background

The real-world application of maintenance in organisations brings together a number of maintenance policies in order to achieve the desired availability, efficiency and profitability. However, the literature mostly chooses a single maintenance policy, and so the decision process is not suited to the real conditions in the company to which it is applied. Our study takes a combination of maintenance policies as alternatives, and so conforms to the actual practice of maintenance in organisations. Furthermore, it introduces the possibility of including extra spare parts, or outsourcing maintenance policies. Although the selection of maintenance policies has been applied to many kinds of business and of machine, there is almost no instance of its application to hospitals, and it has never been applied to delivery systems for cytostatic drugs.

Methods

The model uses the fuzzy Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS), which is recognised as being highly suitable for solving group decision-making problems in a fuzzy environment. Fuzzy set theory is also considered to be more proficient than crisp numbers for handling the ambiguity, imprecisions, data scarcity, and uncertainty inherent in decisions made by human beings. The judgements required were obtained from a decision group comprising the heads of facilities maintenance, maintenance of medical equipment, health and safety at work, environment, and programming-admission. The group also included care staff; specifically, the heads of the main clinical services, and the medical supervisors. The model includes original criteria, such as Quality of health care, which measures impact on care as a function of mean availability of each alternative. It also considers Impact on hospital management via the criteria: Working environment in the organisation and Impact on health care; the former criterion measures equality among care services in the hospital, while the latter assesses the effect on regional health cover. The model was built using real data obtained from a state hospital in Spain. The model can also be easily applied to other national and international healthcare organisations, providing weights specific to the criteria. These are produced by a decision group from each healthcare organisation and the alternatives are updated in accordance with what is considered important in each hospital.

Results

The results obtained from the model recommend changing the alternative that is currently in use, Corrective and Preventive Maintenance, to Corrective and Preventive Maintenance plus two spare hoods. This alternative would lead to an availability of 1 (the highest possible) in the systems for preparing personalised cytotoxic drugs, and so the quality of service is therefore very high. Additionally, it could offer services to all the users of the hospital, and also offer cover in the preparation of cytotoxic medicines to other hospitals in the catchment area.

Conclusions

The results suggest the possibility that improvements to the support and logistical systems, which include maintenance, traditionally held to have no effect on quality of care, may be key to improving care quality, but also in reducing risk to patients, care and non-care staff, and the environment.
Literature
2.
go back to reference Nguyen TV, Theiss JC, Matney TS. Exposure of pharmacy personnel to mutagenic antineoplastic drugs. Cancer Res. 1982;42(11):4792–6.PubMed Nguyen TV, Theiss JC, Matney TS. Exposure of pharmacy personnel to mutagenic antineoplastic drugs. Cancer Res. 1982;42(11):4792–6.PubMed
6.
go back to reference ASHP. Drug Distribution and Control: Preparation and Handling–Guidelines. American Society of Hospital Pharmacists (ASHP), 2018. ASHP. Drug Distribution and Control: Preparation and Handling–Guidelines. American Society of Hospital Pharmacists (ASHP), 2018.
7.
go back to reference HSE. Control of Substances Hazardous to Health, Health and Safety Executive, United Kingdom, 2013. HSE. Control of Substances Hazardous to Health, Health and Safety Executive, United Kingdom, 2013.
8.
go back to reference Cajaraville G, Tamés MJ. Guía de manejo de medicamentos citostáticos Instituto Oncológico San Sebastián, España; 2018. Cajaraville G, Tamés MJ. Guía de manejo de medicamentos citostáticos Instituto Oncológico San Sebastián, España; 2018.
10.
go back to reference Sessink PJM, Sewell G, Vandenbroucke J. Preventing occupational exposure to cytotoxic and other hazardous drugs European Policy Recommendations; 2016. Sessink PJM, Sewell G, Vandenbroucke J. Preventing occupational exposure to cytotoxic and other hazardous drugs European Policy Recommendations; 2016.
11.
go back to reference Santillo M, Field A, Henderson J, Hogan A, Thoms E, Manomano N, et al. Guidance on Handling Cytotoxics in Clinical Areas in NHS hospitals in UK, July 2018, NHS Pharmaceutical Quality Assurance Committee; 2018. Santillo M, Field A, Henderson J, Hogan A, Thoms E, Manomano N, et al. Guidance on Handling Cytotoxics in Clinical Areas in NHS hospitals in UK, July 2018, NHS Pharmaceutical Quality Assurance Committee; 2018.
13.
go back to reference ISO 55000:2014. Asset management - Overview, principles and terminology. International Standard Organization, 2014. ISO 55000:2014. Asset management - Overview, principles and terminology. International Standard Organization, 2014.
14.
go back to reference Carnero MC. In: Wang J, editor. MCDA techniques in maintenance policy selection, encyclopedia of business analytics and optimization, volume III, chapter 138. Hershey: IGI Gobal; 2014. p. 406–15. Carnero MC. In: Wang J, editor. MCDA techniques in maintenance policy selection, encyclopedia of business analytics and optimization, volume III, chapter 138. Hershey: IGI Gobal; 2014. p. 406–15.
15.
go back to reference Zaeri MS, Shahrabi J, Pariazar M, Morabbi A. A combined multivariate technique and multi criteria decision making to maintenance strategy selection, 2007 IEEE international conference on industrial engineering and engineering management, Singapore; 2007. p. 621–5. Zaeri MS, Shahrabi J, Pariazar M, Morabbi A. A combined multivariate technique and multi criteria decision making to maintenance strategy selection, 2007 IEEE international conference on industrial engineering and engineering management, Singapore; 2007. p. 621–5.
17.
go back to reference Kelly A. Strategic maintenance planning. Oxford: Butterworth-Heinemann; 2006. Kelly A. Strategic maintenance planning. Oxford: Butterworth-Heinemann; 2006.
18.
go back to reference Nakajima S. TPM: introduction to total productive maintenance. Cambridge: Productivity Press Inc.; 1988. Nakajima S. TPM: introduction to total productive maintenance. Cambridge: Productivity Press Inc.; 1988.
27.
go back to reference Jamshidi A, Abbasgholizadeh S, Ait-kadi RD, Ruiz A. In: Guan Y, Liao H, editors. Medical devices Inspection and Maintenance; A Literature Review Proceedings of the 2014 Industrial and systems engineering research conference; 2014. p. 3895–904. Jamshidi A, Abbasgholizadeh S, Ait-kadi RD, Ruiz A. In: Guan Y, Liao H, editors. Medical devices Inspection and Maintenance; A Literature Review Proceedings of the 2014 Industrial and systems engineering research conference; 2014. p. 3895–904.
39.
go back to reference Velasquez M, Hester PT. An analysis of multi-criteria decision making methods. Int J Operation Res. 2013;10(2):56–66. Velasquez M, Hester PT. An analysis of multi-criteria decision making methods. Int J Operation Res. 2013;10(2):56–66.
57.
go back to reference Muinde PM, Muchiri PN, Ikua BW. Maintenance strategy selection using analytic hierarchy process: a case study. J Sustainable Res Eng. 2014;1(4):21–9. Muinde PM, Muchiri PN, Ikua BW. Maintenance strategy selection using analytic hierarchy process: a case study. J Sustainable Res Eng. 2014;1(4):21–9.
63.
go back to reference Houria B, Besbes M, Elaoud B, Masmoudi M, Masmoudi F. Maintenance strategy selection for medical equipments using multiple fuzzy multicriteria decision making approach. In: 45th International Conference on Computers & Industrial Engineering 2015 (CIE45), 28-30 October, Metz, France, Vol 1. Computers & Industrial Engineering; 2015. p 905-912. Houria B, Besbes M, Elaoud B, Masmoudi M, Masmoudi F. Maintenance strategy selection for medical equipments using multiple fuzzy multicriteria decision making approach. In: 45th International Conference on Computers & Industrial Engineering 2015 (CIE45), 28-30 October, Metz, France, Vol 1. Computers & Industrial Engineering; 2015. p 905-912.
65.
go back to reference Mahfoud H, El Barkany A, El Biyaali A. A hybrid decision-making model for maintenance prioritization in health care systems. Am J Appl Sci. 2016;13(4):439.450.CrossRef Mahfoud H, El Barkany A, El Biyaali A. A hybrid decision-making model for maintenance prioritization in health care systems. Am J Appl Sci. 2016;13(4):439.450.CrossRef
75.
go back to reference Kaufmann A, Gupta MM. Fuzzy mathematical models in engineering and management science. Amsterdam: North Holland; 1988. Kaufmann A, Gupta MM. Fuzzy mathematical models in engineering and management science. Amsterdam: North Holland; 1988.
77.
go back to reference Hwang CL, Yoon K. Multiple Attribute Decision Making: Methods and Applications. New York: A State-of-the-Art Survey; Springer; 1981.CrossRef Hwang CL, Yoon K. Multiple Attribute Decision Making: Methods and Applications. New York: A State-of-the-Art Survey; Springer; 1981.CrossRef
80.
go back to reference Balioti V, Tzimopoulos C, Evangelides C. Multi-Criteria Decision Making Using TOPSIS Method Under Fuzzy Environment. Application in Spillway Selection. Lefkada Island: 3rd EWaS International Conference on Insights on the Water-Energy-Food Nexus; 2018.CrossRef Balioti V, Tzimopoulos C, Evangelides C. Multi-Criteria Decision Making Using TOPSIS Method Under Fuzzy Environment. Application in Spillway Selection. Lefkada Island: 3rd EWaS International Conference on Insights on the Water-Energy-Food Nexus; 2018.CrossRef
89.
go back to reference CEI IEC 61165:2006. Application of Markov techniques, International Electrotechnical Commission, 2006 (IEC: Switzerland). CEI IEC 61165:2006. Application of Markov techniques, International Electrotechnical Commission, 2006 (IEC: Switzerland).
90.
go back to reference Kaufman A. Methods and models of operations research: Prentice-Hall; 1963. Kaufman A. Methods and models of operations research: Prentice-Hall; 1963.
91.
go back to reference Hillier F, Lieberman G. Introduction to operations research. New York: McGraw-Hill Science; 2002. Hillier F, Lieberman G. Introduction to operations research. New York: McGraw-Hill Science; 2002.
92.
go back to reference Taha HA. Investigación de operaciones. México: Prentice-Hall; 2004. Taha HA. Investigación de operaciones. México: Prentice-Hall; 2004.
93.
go back to reference Rojo H, Miranda M. Investigación Operativa. Cadenas de Markov: Facultad de Ingeniería, Universidad de Buenos Aires; 2009. Rojo H, Miranda M. Investigación Operativa. Cadenas de Markov: Facultad de Ingeniería, Universidad de Buenos Aires; 2009.
94.
go back to reference Creus A. Fiabilidad y Seguridad. 2nd ed. Barcelona: Marcombo S.A; 2005. Creus A. Fiabilidad y Seguridad. 2nd ed. Barcelona: Marcombo S.A; 2005.
Metadata
Title
Optimisation of maintenance in delivery systems for cytostatic medicines
Authors
María Carmen Carnero
Andrés Gómez
Publication date
01-12-2021
Publisher
BioMed Central
Published in
BMC Health Services Research / Issue 1/2021
Electronic ISSN: 1472-6963
DOI
https://doi.org/10.1186/s12913-021-07093-w

Other articles of this Issue 1/2021

BMC Health Services Research 1/2021 Go to the issue