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Child's Nervous System
Published in: Child's Nervous System 1/2018

01-01-2018 | Review Paper

Optical coherence tomography as a marker of vision in children with optic pathway gliomas

Authors: Ana Banc, Cristina Stan, Ioan Stefan Florian

Published in: Child's Nervous System | Issue 1/2018

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Abstract

Purpose

Optic pathway gliomas (OPG) represent an important cause of visual loss in pediatric population. The indication of treatment is based on clinical or neuroimaging progression. Visual acuity loss is the most important symptom of disease progression, but children with OPG are frequently unable to complete the testing of visual function. Optical coherence tomography (OCT) was suggested as an objective tool for visual assessment. A literature review was performed in order to determine the role of retinal OCT as a surrogate marker of vision in children with OPG.

Methods

The search was performed using PubMed, Embase, and Web of Science databases and was restricted to articles published in English between 2000 and 2016, with a minimum of ten participants enrolled.

Results

Eleven studies met the eligibility criteria and were included in the present review. Both neurofibromatosis-1 associated and sporadic OPG were investigated.

Conclusions

Retinal OCT is a promising tool to be considered as a screening or follow-up test in children with OPG, and further multicenter research is encouraged.
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Metadata
Title
Optical coherence tomography as a marker of vision in children with optic pathway gliomas
Authors
Ana Banc
Cristina Stan
Ioan Stefan Florian
Publication date
01-01-2018
Publisher
Springer Berlin Heidelberg
Published in
Child's Nervous System / Issue 1/2018
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-017-3578-8

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