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Child's Nervous System
Published in: Child's Nervous System 9/2006

01-09-2006 | Original Paper

Optic pathway glioma: outcome and prognostic factors in a surgical series

Authors: Yong Ahn, Byung-Kyu Cho, Seung-Ki Kim, You-Nam Chung, Chang Sub Lee, Il Han Kim, Sei Won Yang, Hee-Soo Kim, Hyun Jib Kim, Hee-Won Jung, Kyu-Chang Wang

Published in: Child's Nervous System | Issue 9/2006

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Abstract

Objects

The goals of this study were to evaluate the surgical outcomes of optic pathway glioma (OPG) and to analyze the prognostic factors related to the progression-free survival.

Materials and methods

A retrospective review was conducted on 33 patients who underwent surgery for OPG; these included 15 male and 18 female patients with a mean age of 8.3 years. The mean duration of follow-up was 52 months.

Results and conclusions

The preservation rate of ipsilateral vision was 25%, while that of contralateral vision was 83% (P<0.001). There was no remarkable endocrine improvement after surgery. The overall and progression-free survival rates at 5 years were 93.6 and 52.4%, respectively. In our study, the predictors for tumor progression were children younger than 5 years of age (p=0.023) and of female gender (p=0.022). Because of the variable course of OPG, treatment policy should be optimized individually according to patient’s status.
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Metadata
Title
Optic pathway glioma: outcome and prognostic factors in a surgical series
Authors
Yong Ahn
Byung-Kyu Cho
Seung-Ki Kim
You-Nam Chung
Chang Sub Lee
Il Han Kim
Sei Won Yang
Hee-Soo Kim
Hyun Jib Kim
Hee-Won Jung
Kyu-Chang Wang
Publication date
01-09-2006
Publisher
Springer-Verlag
Published in
Child's Nervous System / Issue 9/2006
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-006-0086-7

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