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Published in: International Urogynecology Journal 10/2020

01-10-2020 | Opioids | Original Article

Vaginal hysterectomy with anterior and posterior repair for pelvic organ prolapse under local anesthesia: results of a pilot study

Authors: Stavros Athanasiou, Dimitrios Zacharakis, Themos Grigoriadis, Theodoros Papalios, Eleni Pitsouni, Dimitrios Valsamidis, Sofia Hadzillia

Published in: International Urogynecology Journal | Issue 10/2020

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Abstract

Introduction and hypothesis

Vaginal hysterectomy (VH) and pelvic floor repair (PFR) for the surgical management of pelvic organ prolapse (POP) are usually performed under regional anesthesia. The aim of this study is to evaluate the feasibility of performing VH and PFR under local anesthesia and to compare postoperative pain and patient recovery parameters with patients undergoing the same surgical procedure under regional anesthesia.

Methods

This was a single-center prospective cohort study of women with advanced POP. The standard care group consisted of 20 patients who underwent VH and PFR under a combined spinal-epidural (CSE) block, whereas the local anesthesia group consisted of 20 patients who underwent VH and PFR under local anesthesia and intravenous sedation. Primary outcomes included the intensity of postoperative pain and the percentage of patients with moderate/severe pain. Secondary outcomes included percentage of patients who used opioids, incidence of nausea/vomiting, level of sedation, and patient satisfaction rate.

Results

The median pain intensity at rest was significantly lower in the local anesthesia group at 2 h, 4 h, and 8 h postoperatively (median values: 0 vs 1.9, 0 vs 4.1, and 1 vs 2.7 respectively). The percentage of patients needing opioids was significantly lower for the local anesthesia group (35% vs 95%, p = 0.002). The proportion of patients presenting nausea and vomiting symptoms in the two groups was similar.

Conclusions

Local anesthesia for patients undergoing VH and PFR has been shown to be a viable alternative to regional anesthesia, offering reduced postoperative pain and less opioid use for the first 8 h.
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Metadata
Title
Vaginal hysterectomy with anterior and posterior repair for pelvic organ prolapse under local anesthesia: results of a pilot study
Authors
Stavros Athanasiou
Dimitrios Zacharakis
Themos Grigoriadis
Theodoros Papalios
Eleni Pitsouni
Dimitrios Valsamidis
Sofia Hadzillia
Publication date
01-10-2020
Publisher
Springer International Publishing
Published in
International Urogynecology Journal / Issue 10/2020
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI
https://doi.org/10.1007/s00192-020-04326-0

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