Skip to main content
Top
Published in: BMC Primary Care 1/2022

Open Access 01-12-2022 | Opioids | Research

Opioid prescribing in general practice: an Australian cross-sectional survey

Authors: Sharon Reid, Carolyn Day, Natalie White, Christopher Harrison, Paul Haber, Clare Bayram

Published in: BMC Primary Care | Issue 1/2022

Login to get access

Abstract

Background

Prescribed opioid doses > 100 mg oral morphine equivalent (OME) and/or co-prescribing of sedating psychoactive medications increase the risk of unintentional fatal overdose. We describe general practice encounters where opioids are prescribed and examine high-risk opioid prescribing.

Methods

The 2006–2016 BEACH study data, a rolling national cross-sectional survey of randomly selected GPs, was analysed.

Results

Opioid prescribing increased 2006–2007 to 2015–2016, however, this plateaued across the latter half-decade. From 2012–2016 3,897 GPs recorded 389,700 encounters and at least one opioid was prescribed at 5.2%. Opioid encounters more likely involved males, those 45–64 years, concession card holders and the socioeconomically disadvantaged. GPs more likely to prescribe opioids were 55 years or older, male, Australian graduates, and in regional and remote areas. The most common problems managed with opioids involved chronic non-cancer pain. One-in-ten opioid prescribing episodes involved high-risk doses and 11% involved co-prescription of sedating psychoactive medications. Over one-third of GPs provided other (non-pharmacological) interventions at encounters with opioid prescriptions.

Conclusions

Only 5% of GP encounters involved an opioid prescription. Of concern, were: prescribing for chronic non-cancer pain, potentially high-risk opioid encounters where > 100 OME daily dose was prescribed, and/or there was co-prescription of sedating psychoactive medication. However, approximately one-in-three opioid prescribing encounters involved non-pharmacological interventions.
Literature
1.
go back to reference Leong M, Murnion B, Haber P. Examination of opioid prescribing in Australia from 1992 to 2007. Intern Med J. 2009;39(10):676–81.CrossRef Leong M, Murnion B, Haber P. Examination of opioid prescribing in Australia from 1992 to 2007. Intern Med J. 2009;39(10):676–81.CrossRef
2.
go back to reference Karanges EA, Blanch B, Buckley NA, Pearson S-A. Twenty-five years of prescription opioid use in Australia: a whole-of-population analysis using pharmaceutical claims. Br J Clin Pharmacol. 2016;82(1):255–67.CrossRef Karanges EA, Blanch B, Buckley NA, Pearson S-A. Twenty-five years of prescription opioid use in Australia: a whole-of-population analysis using pharmaceutical claims. Br J Clin Pharmacol. 2016;82(1):255–67.CrossRef
3.
go back to reference Islam MM, McRae IS, Mazumdar S, Taplin S, McKetin R. Prescription opioid analgesics for pain management in Australia: 20 years of dispensing. Intern Med J. 2016;46(8):955–63.CrossRef Islam MM, McRae IS, Mazumdar S, Taplin S, McKetin R. Prescription opioid analgesics for pain management in Australia: 20 years of dispensing. Intern Med J. 2016;46(8):955–63.CrossRef
4.
go back to reference Blanch B, Degnhardt L, Buckley NA, Gisev N, Dobbins T, Karanges EA, et al. Prescription opioid access patterns and factors associated with increasing number of prescribers, pharmacies, and dispensings: an observational study using pharmaceutical claims. Pain Med. 2018;19(6):1170–83.CrossRef Blanch B, Degnhardt L, Buckley NA, Gisev N, Dobbins T, Karanges EA, et al. Prescription opioid access patterns and factors associated with increasing number of prescribers, pharmacies, and dispensings: an observational study using pharmaceutical claims. Pain Med. 2018;19(6):1170–83.CrossRef
5.
go back to reference Pilgrim JL, Yafistham SP, Gaya S, Saar E, Drummer OH. An update on oxycodone: lessons for death investigators in Australia. Forensic Sci Med Pathol. 2015;11(1):3–12.CrossRef Pilgrim JL, Yafistham SP, Gaya S, Saar E, Drummer OH. An update on oxycodone: lessons for death investigators in Australia. Forensic Sci Med Pathol. 2015;11(1):3–12.CrossRef
6.
go back to reference Adewumi A, Hollingworth S, Maravilla J, Connor J, Alati R. Prescribed dose of opioids and overdose: a systematic review and meta-analysis of unintentional prescription opioid overdose. CNS Drugs. 2018;32(2):101–16.CrossRef Adewumi A, Hollingworth S, Maravilla J, Connor J, Alati R. Prescribed dose of opioids and overdose: a systematic review and meta-analysis of unintentional prescription opioid overdose. CNS Drugs. 2018;32(2):101–16.CrossRef
7.
go back to reference Roxburgh A, Hall W, D., Dobbins T, Gisev N, Burns L, Pearson S-A, et al. Trends in heroin and pharmaceutical opioid overdose deaths in Australia. Drug and Alcohol Dependence. 2017;179:291–8. Roxburgh A, Hall W, D., Dobbins T, Gisev N, Burns L, Pearson S-A, et al. Trends in heroin and pharmaceutical opioid overdose deaths in Australia. Drug and Alcohol Dependence. 2017;179:291–8.
8.
go back to reference Monheit B, Pietrzak D, Hocking S. Prescription drug abuse - A timely update. Aust Fam Physician. 2016;45(12):862–6.PubMed Monheit B, Pietrzak D, Hocking S. Prescription drug abuse - A timely update. Aust Fam Physician. 2016;45(12):862–6.PubMed
9.
go back to reference The Royal Australian College of General Practitioners. Prescribing drugs of dependence in general practice, Part A: Clinical governance framework. Melbourne, Victoria: RACGP; 2015. The Royal Australian College of General Practitioners. Prescribing drugs of dependence in general practice, Part A: Clinical governance framework. Melbourne, Victoria: RACGP; 2015.
11.
go back to reference Harrison CM, Charles J, Henderson J, H. B. Opioid prescribing in Australian general practice Medical Journal of Australia. 2012;196(6):380–1. Harrison CM, Charles J, Henderson J, H. B. Opioid prescribing in Australian general practice Medical Journal of Australia. 2012;196(6):380–1.
12.
go back to reference Britt H, Miller GC, Henderson J, Bayram C, Harrison C, Valenti L, et al. General practice activity in Australia 2015–16. Sydney: Sydney University Press; 2016. Britt H, Miller GC, Henderson J, Bayram C, Harrison C, Valenti L, et al. General practice activity in Australia 2015–16. Sydney: Sydney University Press; 2016.
13.
go back to reference Meza RA, Angelis M, Britt H, Miles DA, Seneta E, Bridges-Webb C. Development of sample size models for national general practice surveys. Aust J Public Health. 1995;19(1):34–40.CrossRef Meza RA, Angelis M, Britt H, Miles DA, Seneta E, Bridges-Webb C. Development of sample size models for national general practice surveys. Aust J Public Health. 1995;19(1):34–40.CrossRef
16.
go back to reference Austin PC, Hux JE. A brief note on overlapping confidence intervals. J Vasc Surg. 2002;36(1):194–5.CrossRef Austin PC, Hux JE. A brief note on overlapping confidence intervals. J Vasc Surg. 2002;36(1):194–5.CrossRef
17.
go back to reference Jayawardana S, Forman R, Johnston-Webber C, Campbell A, Berterame S, de Joncheere C, et al. Global consumption of prescription opioid analgesics between 2009–2019: a country-level observational study. EClinicalMedicine. 2021;42:101198-. Jayawardana S, Forman R, Johnston-Webber C, Campbell A, Berterame S, de Joncheere C, et al. Global consumption of prescription opioid analgesics between 2009–2019: a country-level observational study. EClinicalMedicine. 2021;42:101198-.
18.
go back to reference Henderson JV, Harrison CM, Britt HC, Bayram CF, Miller GC. Prevalence, causes, severity, impact, and management of chronic pain in Australian general practice patients. Pain Med. 2013;14(9):1346–61.CrossRef Henderson JV, Harrison CM, Britt HC, Bayram CF, Miller GC. Prevalence, causes, severity, impact, and management of chronic pain in Australian general practice patients. Pain Med. 2013;14(9):1346–61.CrossRef
19.
go back to reference Dow A. Big pharma under fire for spruiking strong painkillers to doctors. Sydney Morning Herald. 2018;2018:3. Dow A. Big pharma under fire for spruiking strong painkillers to doctors. Sydney Morning Herald. 2018;2018:3.
20.
go back to reference Royal Australian College of General Practitioners. Prescribing drugs of dependence in general practice, Part C1: Opioids. East Melbourne, VIC: RACGP; 2017. Royal Australian College of General Practitioners. Prescribing drugs of dependence in general practice, Part C1: Opioids. East Melbourne, VIC: RACGP; 2017.
21.
go back to reference Cliff BQ, AvanceÑA ALV, Hirth RA, Lee SYD. The Impact of Choosing Wisely Interventions on Low-Value Medical Services: A Systematic Review. Milbank Q. 2021;99(4):1024–58.CrossRef Cliff BQ, AvanceÑA ALV, Hirth RA, Lee SYD. The Impact of Choosing Wisely Interventions on Low-Value Medical Services: A Systematic Review. Milbank Q. 2021;99(4):1024–58.CrossRef
22.
go back to reference McCoy J, Nielsen S, Bruno R. A prospective cohort study evaluating the impact of upscheduling codeine in Australia among frequent users of codeine. Addiction (Abingdon, England). 2022;117(3):677–86.CrossRef McCoy J, Nielsen S, Bruno R. A prospective cohort study evaluating the impact of upscheduling codeine in Australia among frequent users of codeine. Addiction (Abingdon, England). 2022;117(3):677–86.CrossRef
23.
go back to reference Lalic S, Gisev N, Bell JS, Korhonen MJ, Ilomäki J. Predictors of persistent prescription opioid analgesic use among people without cancer in Australia: Predictors of persistent opioid use in people without cancer. Br J Clin Pharmacol. 2018;84(6):1267–78.CrossRef Lalic S, Gisev N, Bell JS, Korhonen MJ, Ilomäki J. Predictors of persistent prescription opioid analgesic use among people without cancer in Australia: Predictors of persistent opioid use in people without cancer. Br J Clin Pharmacol. 2018;84(6):1267–78.CrossRef
24.
go back to reference Australian Institute of Health and Welfare. National Drug Strategy Household Survey 2016: Detailed findings. Canberra: AIHW; 2017. Australian Institute of Health and Welfare. National Drug Strategy Household Survey 2016: Detailed findings. Canberra: AIHW; 2017.
25.
go back to reference Larance B, Campbell G, Peacock A, Nielsen S, Bruno R, Hall W, et al. Pain, alcohol use disorders and risky patterns of drinking among people with chronic non-cancer pain receiving long-term opioid therapy. Drug Alcohol Depend. 2016;162:79–87.CrossRef Larance B, Campbell G, Peacock A, Nielsen S, Bruno R, Hall W, et al. Pain, alcohol use disorders and risky patterns of drinking among people with chronic non-cancer pain receiving long-term opioid therapy. Drug Alcohol Depend. 2016;162:79–87.CrossRef
26.
go back to reference Campbell G, Nielsen S, Bruno R, Lintzeris N, Cohen M, Hall WD, et al. The pain and opioids in treatment study: characteristics of a cohort using opioids to manage chronic non-cancer pain. Pain. 2015;156(2):231–42.CrossRef Campbell G, Nielsen S, Bruno R, Lintzeris N, Cohen M, Hall WD, et al. The pain and opioids in treatment study: characteristics of a cohort using opioids to manage chronic non-cancer pain. Pain. 2015;156(2):231–42.CrossRef
27.
go back to reference Rintoul AC, Diobbin MDH, Drummer OH, Ozanne-Smith J. Increasing deaths involving oxycodone, Victoria, Australia, 2000–09. Inj Prev. 2011;17:254–9.CrossRef Rintoul AC, Diobbin MDH, Drummer OH, Ozanne-Smith J. Increasing deaths involving oxycodone, Victoria, Australia, 2000–09. Inj Prev. 2011;17:254–9.CrossRef
28.
go back to reference Campbell G, Nielsen S, Larance B, Bruno R, Mattick R, Hall W, et al. Pharmaceutical opioid use and dependence among people living with chronic pain: associations observed within the Pain and Opioids in Treatment (POINT) cohort Pain Medicine. 2015;16(9):1745–58. Campbell G, Nielsen S, Larance B, Bruno R, Mattick R, Hall W, et al. Pharmaceutical opioid use and dependence among people living with chronic pain: associations observed within the Pain and Opioids in Treatment (POINT) cohort Pain Medicine. 2015;16(9):1745–58.
Metadata
Title
Opioid prescribing in general practice: an Australian cross-sectional survey
Authors
Sharon Reid
Carolyn Day
Natalie White
Christopher Harrison
Paul Haber
Clare Bayram
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Primary Care / Issue 1/2022
Electronic ISSN: 2731-4553
DOI
https://doi.org/10.1186/s12875-022-01783-y

Other articles of this Issue 1/2022

BMC Primary Care 1/2022 Go to the issue