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Published in: Journal of Urban Health 6/2020

01-12-2020 | Opioids

Geospatial Variations and Neighborhood Deprivation in Drug-Related Admissions and Overdoses

Authors: Julien Cobert, Paul M. Lantos, Mark M. Janko, David G. A. Williams, Karthik Raghunathan, Vijay Krishnamoorthy, Eric A. JohnBull, Atilio Barbeito, Padma Gulur

Published in: Journal of Urban Health | Issue 6/2020

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Abstract

Drug overdoses are a national and global epidemic. However, while overdoses are inextricably linked to social, demographic, and geographical determinants, geospatial patterns of drug-related admissions and overdoses at the neighborhood level remain poorly studied. The objective of this paper is to investigate spatial distributions of patients admitted for drug-related admissions and overdoses from a large, urban, tertiary care center using electronic health record data. Additionally, these spatial distributions were adjusted for a validated socioeconomic index called the Area Deprivation Index (ADI). We showed spatial heterogeneity in patients admitted for opioid, amphetamine, and psychostimulant-related diagnoses and overdoses. While ADI was associated with drug-related admissions, it did not correct for spatial variations and could not account alone for this spatial heterogeneity.
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Literature
1.
go back to reference Visconti AJ, Santos GM, Lemos NP, Burke C, Coffin PO. Opioid overdose deaths in the city and county of San Francisco: prevalence, distribution, and disparities. J Urban Health. 2015;92(4):758–72.CrossRef Visconti AJ, Santos GM, Lemos NP, Burke C, Coffin PO. Opioid overdose deaths in the city and county of San Francisco: prevalence, distribution, and disparities. J Urban Health. 2015;92(4):758–72.CrossRef
2.
go back to reference Garfield J. E D: fatal overdose trends in major us cities: 1990–1997. Addiction Research & Thery. 2001;9(5):425–36.CrossRef Garfield J. E D: fatal overdose trends in major us cities: 1990–1997. Addiction Research & Thery. 2001;9(5):425–36.CrossRef
3.
go back to reference Brownstein JS, Green TC, Cassidy TA, Butler SF. Geographic information systems and pharmacoepidemiology: using spatial cluster detection to monitor local patterns of prescription opioid abuse. Pharmacoepidemiol Drug Saf. 2010;19(6):627–37.CrossRef Brownstein JS, Green TC, Cassidy TA, Butler SF. Geographic information systems and pharmacoepidemiology: using spatial cluster detection to monitor local patterns of prescription opioid abuse. Pharmacoepidemiol Drug Saf. 2010;19(6):627–37.CrossRef
4.
go back to reference Havens JR, Talbert JC, Walker R, Leedham C, Leukefeld CG. Trends in controlled-release oxycodone (OxyContin) prescribing among Medicaid recipients in Kentucky, 1998-2002. J Rural Health. 2006;22(3):276–8.CrossRef Havens JR, Talbert JC, Walker R, Leedham C, Leukefeld CG. Trends in controlled-release oxycodone (OxyContin) prescribing among Medicaid recipients in Kentucky, 1998-2002. J Rural Health. 2006;22(3):276–8.CrossRef
5.
go back to reference Dasgupta N, Jonsson Funk M, Brownstein J. Comparing unintentional opioid poisoning mortality in metropolitan and non-metropolitan counties, United States, 1999–2003. In: Thomas Y, Richardson D, Cheung I, editors. Geography and drug addiction. New York: Springer; 2008. Dasgupta N, Jonsson Funk M, Brownstein J. Comparing unintentional opioid poisoning mortality in metropolitan and non-metropolitan counties, United States, 1999–2003. In: Thomas Y, Richardson D, Cheung I, editors. Geography and drug addiction. New York: Springer; 2008.
6.
go back to reference McLafferty S. Placing substance abuse. In: Thomas Y, Richardson D, Cheung I, editors. Geography and drug addiction. New York: Springer; 2008. McLafferty S. Placing substance abuse. In: Thomas Y, Richardson D, Cheung I, editors. Geography and drug addiction. New York: Springer; 2008.
7.
go back to reference Paulozzi LJ, Ryan GW. Opioid analgesics and rates of fatal drug poisoning in the United States. Am J Prev Med. 2006;31(6):506–11.CrossRef Paulozzi LJ, Ryan GW. Opioid analgesics and rates of fatal drug poisoning in the United States. Am J Prev Med. 2006;31(6):506–11.CrossRef
8.
go back to reference Paulozzi LJ, Xi Y. Recent changes in drug poisoning mortality in the United States by urban-rural status and by drug type. Pharmacoepidemiol Drug Saf. 2008;17(10):997–1005.CrossRef Paulozzi LJ, Xi Y. Recent changes in drug poisoning mortality in the United States by urban-rural status and by drug type. Pharmacoepidemiol Drug Saf. 2008;17(10):997–1005.CrossRef
9.
go back to reference Rigg KK, Monnat SM, Chavez MN. Opioid-related mortality in rural America: geographic heterogeneity and intervention strategies. Int J Drug Policy. 2018;57:119–29.CrossRef Rigg KK, Monnat SM, Chavez MN. Opioid-related mortality in rural America: geographic heterogeneity and intervention strategies. Int J Drug Policy. 2018;57:119–29.CrossRef
10.
go back to reference Zerzan JT, Morden NE, Soumerai S, Ross-Degnan D, Roughead E, Zhang F, et al. Trends and geographic variation of opiate medication use in state Medicaid fee-for-service programs, 1996 to 2002. Med Care. 2006;44(11):1005–10.CrossRef Zerzan JT, Morden NE, Soumerai S, Ross-Degnan D, Roughead E, Zhang F, et al. Trends and geographic variation of opiate medication use in state Medicaid fee-for-service programs, 1996 to 2002. Med Care. 2006;44(11):1005–10.CrossRef
11.
go back to reference Health UoWSoMaP: Area Deprivation Index. v2.0 edn. Madison, WI; 2015. Health UoWSoMaP: Area Deprivation Index. v2.0 edn. Madison, WI; 2015.
12.
go back to reference Kind AJ, Jencks S, Brock J, Yu M, Bartels C, Ehlenbach W, et al. Neighborhood socioeconomic disadvantage and 30-day rehospitalization: a retrospective cohort study. Ann Intern Med. 2014;161(11):765–74.CrossRef Kind AJ, Jencks S, Brock J, Yu M, Bartels C, Ehlenbach W, et al. Neighborhood socioeconomic disadvantage and 30-day rehospitalization: a retrospective cohort study. Ann Intern Med. 2014;161(11):765–74.CrossRef
13.
go back to reference Lantos PM, Hoffman K, Permar SR, Jackson P, Hughes BL, Kind A, et al. Neighborhood disadvantage is associated with high cytomegalovirus seroprevalence in pregnancy. J Racial Ethn Health Disparities. 2018;5(4):782–6.CrossRef Lantos PM, Hoffman K, Permar SR, Jackson P, Hughes BL, Kind A, et al. Neighborhood disadvantage is associated with high cytomegalovirus seroprevalence in pregnancy. J Racial Ethn Health Disparities. 2018;5(4):782–6.CrossRef
14.
go back to reference Sheets L, Petroski GF, Jaddoo J, Barnett Y, Barnett C, Kelley LEH, et al. The effect of neighborhood disadvantage on diabetes prevalence. AMIA Annu Symp Proc. 2017;2017:1547–53.PubMed Sheets L, Petroski GF, Jaddoo J, Barnett Y, Barnett C, Kelley LEH, et al. The effect of neighborhood disadvantage on diabetes prevalence. AMIA Annu Symp Proc. 2017;2017:1547–53.PubMed
15.
go back to reference Singh GK. Area deprivation and widening inequalities in US mortality, 1969-1998. Am J Public Health. 2003;93(7):1137–43.CrossRef Singh GK. Area deprivation and widening inequalities in US mortality, 1969-1998. Am J Public Health. 2003;93(7):1137–43.CrossRef
16.
go back to reference Besag J, York J, Mollie A. Bayesian image restoration, with two applications in spatial statistics. Ann Inst Stat Math. 1991;43(1):1–49.CrossRef Besag J, York J, Mollie A. Bayesian image restoration, with two applications in spatial statistics. Ann Inst Stat Math. 1991;43(1):1–49.CrossRef
17.
go back to reference Cerda M, Ransome Y, Keyes KM, Koenen KC, Tardiff K, Vlahov D, et al. Revisiting the role of the urban environment in substance use: the case of analgesic overdose fatalities. Am J Public Health. 2013;103(12):2252–60.CrossRef Cerda M, Ransome Y, Keyes KM, Koenen KC, Tardiff K, Vlahov D, et al. Revisiting the role of the urban environment in substance use: the case of analgesic overdose fatalities. Am J Public Health. 2013;103(12):2252–60.CrossRef
18.
go back to reference Cerda M, Ransome Y, Keyes KM, Koenen KC, Tracy M, Tardiff KJ, et al. Prescription opioid mortality trends in New York City, 1990-2006: examining the emergence of an epidemic. Drug Alcohol Depend. 2013;132(1–2):53–62.CrossRef Cerda M, Ransome Y, Keyes KM, Koenen KC, Tracy M, Tardiff KJ, et al. Prescription opioid mortality trends in New York City, 1990-2006: examining the emergence of an epidemic. Drug Alcohol Depend. 2013;132(1–2):53–62.CrossRef
19.
go back to reference Green CR, Ndao-Brumblay SK, West B, Washington T. Differences in prescription opioid analgesic availability: comparing minority and white pharmacies across Michigan. J Pain. 2005;6(10):689–99.CrossRef Green CR, Ndao-Brumblay SK, West B, Washington T. Differences in prescription opioid analgesic availability: comparing minority and white pharmacies across Michigan. J Pain. 2005;6(10):689–99.CrossRef
20.
go back to reference Burgess DJ, Phelan S, Workman M, Hagel E, Nelson DB, Fu SS, et al. The effect of cognitive load and patient race on physicians’ decisions to prescribe opioids for chronic low back pain: a randomized trial. Pain Med. 2014;15(6):965–74.CrossRef Burgess DJ, Phelan S, Workman M, Hagel E, Nelson DB, Fu SS, et al. The effect of cognitive load and patient race on physicians’ decisions to prescribe opioids for chronic low back pain: a randomized trial. Pain Med. 2014;15(6):965–74.CrossRef
21.
go back to reference Piercefield E, Archer P, Kemp P, Mallonee S. Increase in unintentional medication overdose deaths: Oklahoma, 1994-2006. Am J Prev Med. 2010;39(4):357–63.CrossRef Piercefield E, Archer P, Kemp P, Mallonee S. Increase in unintentional medication overdose deaths: Oklahoma, 1994-2006. Am J Prev Med. 2010;39(4):357–63.CrossRef
22.
go back to reference Hall AJ, Logan JE, Toblin RL, Kaplan JA, Kraner JC, Bixler D, et al. Patterns of abuse among unintentional pharmaceutical overdose fatalities. JAMA. 2008;300(22):2613–20.CrossRef Hall AJ, Logan JE, Toblin RL, Kaplan JA, Kraner JC, Bixler D, et al. Patterns of abuse among unintentional pharmaceutical overdose fatalities. JAMA. 2008;300(22):2613–20.CrossRef
23.
go back to reference Joynt M, Train MK, Robbins BW, Halterman JS, Caiola E, Fortuna RJ. The impact of neighborhood socioeconomic status and race on the prescribing of opioids in emergency departments throughout the United States. J Gen Intern Med. 2013;28(12):1604–10.CrossRef Joynt M, Train MK, Robbins BW, Halterman JS, Caiola E, Fortuna RJ. The impact of neighborhood socioeconomic status and race on the prescribing of opioids in emergency departments throughout the United States. J Gen Intern Med. 2013;28(12):1604–10.CrossRef
24.
go back to reference Ndlovu M, Bedson J, Jones PW, Jordan KP. Pain medication management of musculoskeletal conditions at first presentation in primary care: analysis of routinely collected medical record data. BMC Musculoskelet Disord. 2014;15:418.CrossRef Ndlovu M, Bedson J, Jones PW, Jordan KP. Pain medication management of musculoskeletal conditions at first presentation in primary care: analysis of routinely collected medical record data. BMC Musculoskelet Disord. 2014;15:418.CrossRef
25.
go back to reference Gebauer S, Salas J, Scherrer JF. Neighborhood socioeconomic status and receipt of opioid medication for new back pain diagnosis. J Am Board Fam Med. 2017;30(6):775–83.CrossRef Gebauer S, Salas J, Scherrer JF. Neighborhood socioeconomic status and receipt of opioid medication for new back pain diagnosis. J Am Board Fam Med. 2017;30(6):775–83.CrossRef
26.
go back to reference Durfey SNM, Kind AJH, Buckingham WR, DuGoff EH, Trivedi AN. Neighborhood disadvantage and chronic disease management. Health Serv Res. 2019;54(Suppl 1):206–16.CrossRef Durfey SNM, Kind AJH, Buckingham WR, DuGoff EH, Trivedi AN. Neighborhood disadvantage and chronic disease management. Health Serv Res. 2019;54(Suppl 1):206–16.CrossRef
27.
go back to reference Ho JY. The contribution of drug overdose to educational gradients in life expectancy in the United States, 1992-2011. Demography. 2017;54(3):1175–202.CrossRef Ho JY. The contribution of drug overdose to educational gradients in life expectancy in the United States, 1992-2011. Demography. 2017;54(3):1175–202.CrossRef
28.
go back to reference Pouget ER, Fong C, Rosenblum A. Racial/ethnic differences in prevalence trends for heroin use and non-medical use of prescription opioids among entrants to opioid treatment programs, 2005-2016. Subst Use Misuse. 2018;53(2):290–300.CrossRef Pouget ER, Fong C, Rosenblum A. Racial/ethnic differences in prevalence trends for heroin use and non-medical use of prescription opioids among entrants to opioid treatment programs, 2005-2016. Subst Use Misuse. 2018;53(2):290–300.CrossRef
29.
go back to reference McClellan CB. Disparities in opioid related mortality between United States counties from 2000 to 2014. Drug Alcohol Depend. 2019;199:151–8.CrossRef McClellan CB. Disparities in opioid related mortality between United States counties from 2000 to 2014. Drug Alcohol Depend. 2019;199:151–8.CrossRef
30.
go back to reference Mosher H, Zhou Y, Thurman AL, Sarrazin MV, Ohl ME. Trends in hospitalization for opioid overdose among rural compared to urban residents of the United States, 2007-2014. J Hosp Med. 2017;12(11):925–9.CrossRef Mosher H, Zhou Y, Thurman AL, Sarrazin MV, Ohl ME. Trends in hospitalization for opioid overdose among rural compared to urban residents of the United States, 2007-2014. J Hosp Med. 2017;12(11):925–9.CrossRef
31.
go back to reference Wagner J, Neitzke-Spruill L, O’Connell D, Highberger J, Martin SS, Walker R, et al. Understanding geographic and neighborhood variations in overdose death rates. J Community Health. 2019;44(2):272–83.CrossRef Wagner J, Neitzke-Spruill L, O’Connell D, Highberger J, Martin SS, Walker R, et al. Understanding geographic and neighborhood variations in overdose death rates. J Community Health. 2019;44(2):272–83.CrossRef
32.
go back to reference Strom BL. Data validity issues in using claims data. Pharmacoepidemiol Drug Saf. 2001;10(5):389–92.CrossRef Strom BL. Data validity issues in using claims data. Pharmacoepidemiol Drug Saf. 2001;10(5):389–92.CrossRef
33.
go back to reference Seth P, Scholl L, Rudd RA, Bacon S. Overdose deaths involving opioids, cocaine, and psychostimulants - United States, 2015-2016. MMWR Morb Mortal Wkly Rep. 2018;67(12):349–58.CrossRef Seth P, Scholl L, Rudd RA, Bacon S. Overdose deaths involving opioids, cocaine, and psychostimulants - United States, 2015-2016. MMWR Morb Mortal Wkly Rep. 2018;67(12):349–58.CrossRef
34.
go back to reference Presription Drug Overdose Data & Statistics - Guide to ICD-9-CM and ICD-10 Codes Related to Poisoning and Pain. In: Prevention DoUI, Version 1.3 editor. Atlanta, GA: National Center for Injury Prevention and Control - Centers for Disease Control and Prevention; 2013. Presription Drug Overdose Data & Statistics - Guide to ICD-9-CM and ICD-10 Codes Related to Poisoning and Pain. In: Prevention DoUI, Version 1.3 editor. Atlanta, GA: National Center for Injury Prevention and Control - Centers for Disease Control and Prevention; 2013.
Metadata
Title
Geospatial Variations and Neighborhood Deprivation in Drug-Related Admissions and Overdoses
Authors
Julien Cobert
Paul M. Lantos
Mark M. Janko
David G. A. Williams
Karthik Raghunathan
Vijay Krishnamoorthy
Eric A. JohnBull
Atilio Barbeito
Padma Gulur
Publication date
01-12-2020
Publisher
Springer US
Keywords
Opioids
Opioids
Published in
Journal of Urban Health / Issue 6/2020
Print ISSN: 1099-3460
Electronic ISSN: 1468-2869
DOI
https://doi.org/10.1007/s11524-020-00436-8

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