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Published in: Knee Surgery, Sports Traumatology, Arthroscopy 7/2023

07-12-2022 | Knee

Opening- and closing-wedge high tibial osteotomy are comparable and early full weight bearing is safe with angular stable plate fixation: a meta-analysis

Authors: M. H. van Haeringen, P. P. F. M. Kuijer, J. G. Daams, R. C. I. van Geenen, J. M. Brinkman, G. M. M. J. Kerkhoffs, R. J. van Heerwaarden, A. Hoorntje

Published in: Knee Surgery, Sports Traumatology, Arthroscopy | Issue 7/2023

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Abstract

Purpose

The purpose of this study was to establish the gold standard for surgical technique, fixation, and rehabilitation for HTO in patients with unicompartmental knee osteoarthritis.

Methods

Medline, Embase, and SPORTDiscus databases were searched up to April 2022. Included were (1) randomized controlled trials (RCTs) comparing opening-wedge HTO (owHTO) and closing-wedge HTO (cwHTO), (2) biomechanical studies and prospective patient studies comparing biomechanical and clinical results for plate fixators, and (3) RCTs comparing an early versus delayed full-weight-bearing (FWB) protocol.

Results

The pooled results for the surgical technique showed no significant differences between owHTO and cwHTO for most PROMs on pain, activity, and risk for conversion to TKA. The cwHTO group showed a slightly better improvement in KOOS/WOMAC pain scores (4.51; 95% CI 1.18–7.85), and a significantly lower change in posterior tibial slope (p = 0.03). The pooled results for the fixation method showed the highest force at maximum failure for the Activmotion (Newclip Technics, France), Aescula (B. Braun Korea, Korea), 2nd generation Puddu (Arthrex Inc., USA), and TomoFix plate (Depuy Synthes, Switzerland). The pooled results for the rehabilitation protocol showed no significant differences between the early full-weight-bearing (FWB) group and the delayed FWB group for functional scores, complication rates, and delayed unions.

Conclusion

Both owHTO and cwHTO reduced pain and improved knee function. Locking plate fixation should be used for owHTO. An early FWB protocol has proven to be safe in patients with small corrections, no hinge fractures, and non-smokers.

Level of evidence

Level II.
Appendix
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Metadata
Title
Opening- and closing-wedge high tibial osteotomy are comparable and early full weight bearing is safe with angular stable plate fixation: a meta-analysis
Authors
M. H. van Haeringen
P. P. F. M. Kuijer
J. G. Daams
R. C. I. van Geenen
J. M. Brinkman
G. M. M. J. Kerkhoffs
R. J. van Heerwaarden
A. Hoorntje
Publication date
07-12-2022
Publisher
Springer Berlin Heidelberg
Published in
Knee Surgery, Sports Traumatology, Arthroscopy / Issue 7/2023
Print ISSN: 0942-2056
Electronic ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-022-07229-3

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Knee Surgery, Sports Traumatology, Arthroscopy 7/2023 Go to the issue