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Published in: Indian Journal of Surgical Oncology 3/2016

01-09-2016 | Original Article

Oncological Safety of Breast Conservation Surgery in Young Females

Authors: Madhu Muralee, Arun Peter Mathew, Kurian Cherian, K. Chandramohan, Paul Augustine, Jem Prabhakar, Iqbal Ahamed

Published in: Indian Journal of Surgical Oncology | Issue 3/2016

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Abstract

Breast conservation surgery (BCS) is the standard of care in early breast cancer. The oncological safety of this procedure has been proven beyond doubt in several randomised control trials. But there are concerns regarding the safety of this procedure in young females. The concern is regarding increased risk of local recurrence. This issue has not been addressed in any major trial. In this prospective study we intend to look into the oncological safety of BCS in young patients who are less than forty years of age.
Literature
1.
go back to reference Colleoni M, Rotmensz N, Robertson C, Orlando L, Viale G, Renne G, et al. (2002) Very young women(<35 years) withoperable breastcancer: featuresofdiseaseat presentation. Ann Oncol 13(2):273–279CrossRefPubMed Colleoni M, Rotmensz N, Robertson C, Orlando L, Viale G, Renne G, et al. (2002) Very young women(<35 years) withoperable breastcancer: featuresofdiseaseat presentation. Ann Oncol 13(2):273–279CrossRefPubMed
2.
go back to reference Bartelink H, Horiot JC, Poortmans P, Struikmans H, Van den Bogaert W, Barillot I, et al. (2001) Recurrence rates after treatment of breast cancer with standard radiotherapy with or without additional radiation. N Engl J Med 345(19):1378–1387CrossRefPubMed Bartelink H, Horiot JC, Poortmans P, Struikmans H, Van den Bogaert W, Barillot I, et al. (2001) Recurrence rates after treatment of breast cancer with standard radiotherapy with or without additional radiation. N Engl J Med 345(19):1378–1387CrossRefPubMed
3.
go back to reference De Bock GH, van der Hage JA, Putter H, Bonnema J, Bartelink H, van de Velde CJ (2006) Isolated loco-regional recurrence of breast cancer is more common in young patients and following breast conserving therapy: long-term results of European Organisation for Research and Treatment of Cancer studies. Eur J Cancer 42(3):351–356CrossRefPubMed De Bock GH, van der Hage JA, Putter H, Bonnema J, Bartelink H, van de Velde CJ (2006) Isolated loco-regional recurrence of breast cancer is more common in young patients and following breast conserving therapy: long-term results of European Organisation for Research and Treatment of Cancer studies. Eur J Cancer 42(3):351–356CrossRefPubMed
4.
go back to reference Buckley JM, Coopey S, Samphao S, et al: Recurrence rates and long-term survival in women diagnosed with breast cancer at age 40 and younger. 2011 Breast Cancer Symposium. Abstract 70. Presented September 8, 2011. Buckley JM, Coopey S, Samphao S, et al: Recurrence rates and long-term survival in women diagnosed with breast cancer at age 40 and younger. 2011 Breast Cancer Symposium. Abstract 70. Presented September 8, 2011.
5.
go back to reference VanNes JGH, van de Velde CJH (2006) The preferred treatment for young women with breast cancer – mastectomy versus breast conservation. Breast 15(Suppl. 2):S3–10CrossRef VanNes JGH, van de Velde CJH (2006) The preferred treatment for young women with breast cancer – mastectomy versus breast conservation. Breast 15(Suppl. 2):S3–10CrossRef
6.
go back to reference Mariani L, Salvadori B, Marubini E, Conti AR, Rovini D, Cusumano F, et al. (1998) Ten year results of a randomised trial comparing two conservative treatment strategies for small size breast cancer. Eur J Cancer 34(8):1156–1162CrossRefPubMed Mariani L, Salvadori B, Marubini E, Conti AR, Rovini D, Cusumano F, et al. (1998) Ten year results of a randomised trial comparing two conservative treatment strategies for small size breast cancer. Eur J Cancer 34(8):1156–1162CrossRefPubMed
7.
go back to reference Gentilini O, Botteri E, Rotmensz N, Toesca A, De Oliveira H, Veronesi U, et al. (2010) Breast-conserving surgery in 201 very young patients (<35 years). Breast 19:55–58CrossRefPubMed Gentilini O, Botteri E, Rotmensz N, Toesca A, De Oliveira H, Veronesi U, et al. (2010) Breast-conserving surgery in 201 very young patients (<35 years). Breast 19:55–58CrossRefPubMed
Metadata
Title
Oncological Safety of Breast Conservation Surgery in Young Females
Authors
Madhu Muralee
Arun Peter Mathew
Kurian Cherian
K. Chandramohan
Paul Augustine
Jem Prabhakar
Iqbal Ahamed
Publication date
01-09-2016
Publisher
Springer India
Published in
Indian Journal of Surgical Oncology / Issue 3/2016
Print ISSN: 0975-7651
Electronic ISSN: 0976-6952
DOI
https://doi.org/10.1007/s13193-016-0535-z

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