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International Ophthalmology
Published in: International Ophthalmology 3/2019

01-03-2019 | Case Report

Ocular surface squamous neoplasia in a setting of fungal keratitis: a rare co-occurrence

Authors: Swati Singh, Ruchi Mittal, Purvasha Narang, Vikas Mittal

Published in: International Ophthalmology | Issue 3/2019

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Abstract

Purpose

To describe a rare co-occurrence of ocular surface squamous neoplasia (OSSN) in a patient with microbial keratitis.

Methods

Case report.

Results

We describe a 68-years female who developed ocular surface squamous neoplasia (OSSN) in an eye with culture proven severe fungal keratitis of 5 months duration, which progressed to endophthalmitis. She was managed with extended enucleation for left eye. Histopathology examination was consistent with squamous cell carcinoma of ocular surface with no corneal stromal/scleral/anterior chamber involvement. She received adjuvant chemotherapy with topical Interferon alpha2b (3 cycles) for positive margins. Six months after treatment, she is completely tumor free.

Conclusion

Co-occurrence of OSSN and chronic fungal keratitis is rare. We recommend that patients with chronic ocular infections should be examined and followed closely for abnormally thickened limbal areas.
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Metadata
Title
Ocular surface squamous neoplasia in a setting of fungal keratitis: a rare co-occurrence
Authors
Swati Singh
Ruchi Mittal
Purvasha Narang
Vikas Mittal
Publication date
01-03-2019
Publisher
Springer Netherlands
Published in
International Ophthalmology / Issue 3/2019
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI
https://doi.org/10.1007/s10792-018-0864-8

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