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Drugs
Published in: Drugs 18/2005

01-12-2005 | Adis Drug Profile

Octocog alfa, Plasma/Albumin-Free Method

A Viewpoint by Jørgen Ingerslev

Author: Jørgen Ingerslev

Published in: Drugs | Issue 18/2005

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Excerpt

Substitution therapy with a concentrate of coagulation factor VIII is the mainstay in the management of bleeding episodes in patients with classic congenital haemophilia A. In the manufacture of factor VIII, plasma from healthy donors was the major source of material until products derived from recombinant DNA technologies became available in the mid-1990s. Owing to the high incidence of transmission of health- and life-threatening human pathogens, such as HIV and hepatitis C virus, from plasma-derived products, the new recombinant factor VIII concentrates were seen as a major safety advantage for recipients. …
Metadata
Title
Octocog alfa, Plasma/Albumin-Free Method
A Viewpoint by Jørgen Ingerslev
Author
Jørgen Ingerslev
Publication date
01-12-2005
Publisher
Springer International Publishing
Published in
Drugs / Issue 18/2005
Print ISSN: 0012-6667
Electronic ISSN: 1179-1950
DOI
https://doi.org/10.2165/00003495-200565180-00007

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