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Clinical Oral Investigations

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Open Access 01-03-2021 | Original Article

OCT evaluation of orthodontic surface sealants: a 12-month follow-up randomized clinical trial

Authors: Sinan Şen, Ralf Erber, Gül Orhan, Sebastian Zingler, Christopher J. Lux

Published in: Clinical Oral Investigations | Issue 3/2021

Abstract

Objectives

The aim of this single-center randomized controlled trial (NCT03753256) was to assess orthodontic surface sealant layer thickness and integrity in vivo during a 12-month follow-up by optical coherence tomography (OCT).

Materials and methods

Using a split-mouth design, quadrants of 20 patients treated with fixed orthodontic appliances were included. Quadrants were randomly assigned to the sealants Pro Seal® (PS) or Opal® Seal™ (OS). OCT scans were performed immediately after the application of the sealants and after 3, 6, 9, and 12 months. Sealant layer thicknesses and their integrity were determined at 5 regions of interest (ROIs) known for high risks of demineralization. Sealant integrity loss was determined using a self-developed scale.

Results

A total of 16 patients successfully completed the study. The studied sealants showed significant differences in initial layer thickness. Mean layer thickness was significantly lower for PS (67.8 μm, (95% CI, 56.1–79.5)) than for OS (110.7 μm, (95% CI, 97.3–124.1)). Layer thickness loss was significant after 3 months for PS and after 6 months for OS. Sealant integrity was compromised in more than 50% of the ROIs already after 3 months for both sealants.

Conclusions

Patients treated with fixed orthodontic surface sealants lost the integrity of the protective layer in more than 50% of cases after 3 months, and the layer thickness of the sealants was significantly reduced after 3–6 months.

Clinical relevance

The protective effect against demineralization lesions of orthodontic sealants in patients treated with fixed appliances appears to be limited in time. Further preventive measures should be investigated.

Trial registration

ClinicalTrials.gov (NCT 03753256)

Available only for authorised users

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Title: OCT evaluation of orthodontic surface sealants: a 12-month follow-up randomized clinical trial
Authors: Sinan Şen
Ralf Erber
Gül Orhan
Sebastian Zingler
Christopher J. Lux
Publication date: 01-03-2021
Publisher: Springer Berlin Heidelberg
Published in: Clinical Oral Investigations / Issue 3/2021
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI: https://doi.org/10.1007/s00784-020-03462-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

OCT evaluation of orthodontic surface sealants: a 12-month follow-up randomized clinical trial

Abstract

Objectives

Materials and methods

Results

Conclusions

Clinical relevance

Trial registration

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Materials and methods

Results

Conclusions

Clinical relevance

Trial registration

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