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Published in: Indian Journal of Hematology and Blood Transfusion 1/2016

01-06-2016 | Correspondence

Occurrence of Double Monoclonal Bands on Protein Electrophoresis: An Unusual Finding

Authors: Vishrut K Srinivasan, Priyanka Bhagat, Frainey Bansal, Seema Chhabra

Published in: Indian Journal of Hematology and Blood Transfusion | Special Issue 1/2016

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Abstract

Various techniques of protein electrophoresis are used for detection of monoclonal proteins/paraproteins in serum and/or urine of patients with monoclonal gammopathies. These are detected as the so-called ‘M’ bands (monoclonal bands) on serum protein electrophoresis and/or immunofixation electrophoresis. In most cases, a single M-band is detected. However, more than one M-band can be detected in the samples of a minor proportion of patients. This condition is termed as ‘double gammopathy’ or ‘biclonal gammopathy’. A knowledge of such an unusual occurrence is essential for recognition and appropriate interpretation of this entity.
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Metadata
Title
Occurrence of Double Monoclonal Bands on Protein Electrophoresis: An Unusual Finding
Authors
Vishrut K Srinivasan
Priyanka Bhagat
Frainey Bansal
Seema Chhabra
Publication date
01-06-2016
Publisher
Springer India
Published in
Indian Journal of Hematology and Blood Transfusion / Issue Special Issue 1/2016
Print ISSN: 0971-4502
Electronic ISSN: 0974-0449
DOI
https://doi.org/10.1007/s12288-015-0622-2

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