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Published in: Current Allergy and Asthma Reports 2/2010

01-03-2010

Occupational Rhinitis and Asthma: Where Do We Stand, Where Do We Go?

Authors: Roberto Castano, Jean-Luc Malo

Published in: Current Allergy and Asthma Reports | Issue 2/2010

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Abstract

This review provides an overview of current and emerging issues regarding occupational rhinitis (OR) and occupational asthma (OA), focusing on studies discussing concepts and results that are relevant to both diseases. OA and OR are conditions that affect the upper and lower airways, are characterized by reduced airway caliber and hyperresponsiveness and by inflammation, and are caused by agents present in the workplace. To explain disease expression, research is moving from the T-helper type 1/type 2 cells paradigm to consider the contribution of diverse alternative pathways such as neural inflammation, a dysfunctional epithelial barrier, and autoimmune mechanisms, among others. Objective assessment of OR and OA has been improved and tested for research and, currently, clinical application. Further developments in the field of OR are expected to lead to more generalized clinical applications, following the example of what has been achieved for OA.
Literature
1.
go back to reference •• Moscato G, Vandenplas O, Gerth VW, et al.: Occupational rhinitis. Allergy 2008, 63:969–980. This was the first position paper on OR covering relevant nosologic, etiopathogenic, and clinical aspects.CrossRefPubMed •• Moscato G, Vandenplas O, Gerth VW, et al.: Occupational rhinitis. Allergy 2008, 63:969–980. This was the first position paper on OR covering relevant nosologic, etiopathogenic, and clinical aspects.CrossRefPubMed
2.
go back to reference •• Tarlo SM, Malo JL; Third Jack Pepys Workshop on Asthma in the Workplace Participants: An official ATS proceedings: asthma in the workplace: the Third Jack Pepys Workshop on Asthma in the Workplace: answered and unanswered questions. Proc Am Thorac Soc 2009, 6:339–349. This is a succinct review on asthma in the workplace that resulted from an international conference held on this topic every 3 years.CrossRefPubMed •• Tarlo SM, Malo JL; Third Jack Pepys Workshop on Asthma in the Workplace Participants: An official ATS proceedings: asthma in the workplace: the Third Jack Pepys Workshop on Asthma in the Workplace: answered and unanswered questions. Proc Am Thorac Soc 2009, 6:339–349. This is a succinct review on asthma in the workplace that resulted from an international conference held on this topic every 3 years.CrossRefPubMed
3.
go back to reference Moscato G, Siracusa A: Rhinitis guidelines and implications for occupational rhinitis. Curr Opin Allergy Clin Immunol 2009, 9:110–115.CrossRefPubMed Moscato G, Siracusa A: Rhinitis guidelines and implications for occupational rhinitis. Curr Opin Allergy Clin Immunol 2009, 9:110–115.CrossRefPubMed
4.
go back to reference Gottesman II, Gould TD: The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry 2003, 160:636–645.CrossRefPubMed Gottesman II, Gould TD: The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry 2003, 160:636–645.CrossRefPubMed
5.
go back to reference • Anderson GP: Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease. Lancet 2008, 372:1107–1119. This interesting article introduced the endophenotype concept for studying the genetic basis of respiratory diseases.CrossRefPubMed • Anderson GP: Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease. Lancet 2008, 372:1107–1119. This interesting article introduced the endophenotype concept for studying the genetic basis of respiratory diseases.CrossRefPubMed
6.
go back to reference Bousquet J, Khaltaev N, Cruz AA, et al.: Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy 2008, 63(Suppl 86):8–160.CrossRefPubMed Bousquet J, Khaltaev N, Cruz AA, et al.: Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy 2008, 63(Suppl 86):8–160.CrossRefPubMed
7.
go back to reference • Castano R, Gautrin D, Theriault G, et al.: Occupational rhinitis in workers investigated for occupational asthma. Thorax 2009, 64:50–54. In this study, the authors demonstrated a concomitant clinically significant reaction of the upper and lower airways after inhalation challenge with occupational agents.CrossRefPubMed • Castano R, Gautrin D, Theriault G, et al.: Occupational rhinitis in workers investigated for occupational asthma. Thorax 2009, 64:50–54. In this study, the authors demonstrated a concomitant clinically significant reaction of the upper and lower airways after inhalation challenge with occupational agents.CrossRefPubMed
8.
go back to reference Maestrelli P, Boschetto P, Fabbri LM, Mapp CE: Mechanisms of occupational asthma. J Allergy Clin Immunol 2009, 123:531–542.CrossRefPubMed Maestrelli P, Boschetto P, Fabbri LM, Mapp CE: Mechanisms of occupational asthma. J Allergy Clin Immunol 2009, 123:531–542.CrossRefPubMed
9.
go back to reference Baraniuk JN, Merck SJ: Neuroregulation of human nasal mucosa. Ann N Y Acad Sci 2009, 1170:604–609.CrossRefPubMed Baraniuk JN, Merck SJ: Neuroregulation of human nasal mucosa. Ann N Y Acad Sci 2009, 1170:604–609.CrossRefPubMed
10.
go back to reference Raap U, Braunstahl GJ: The role of neurotrophins in the pathophysiology of allergic rhinitis. Curr Opin Allergy Clin Immunol 2009 Nov 20 (Epub ahead of print). Raap U, Braunstahl GJ: The role of neurotrophins in the pathophysiology of allergic rhinitis. Curr Opin Allergy Clin Immunol 2009 Nov 20 (Epub ahead of print).
11.
go back to reference Joos GF, Germonpre PR, Pauwels RA: Neural mechanisms in asthma. Clin Exp Allergy 2000, 30(Suppl 1):60–65.CrossRefPubMed Joos GF, Germonpre PR, Pauwels RA: Neural mechanisms in asthma. Clin Exp Allergy 2000, 30(Suppl 1):60–65.CrossRefPubMed
12.
go back to reference Marraccini P, Brass DM, Hollingsworth JW, et al.: Bakery flour dust exposure causes non-allergic inflammation and enhances allergic airway inflammation in mice. Clin Exp Allergy 2008, 38:1526–1535.CrossRefPubMed Marraccini P, Brass DM, Hollingsworth JW, et al.: Bakery flour dust exposure causes non-allergic inflammation and enhances allergic airway inflammation in mice. Clin Exp Allergy 2008, 38:1526–1535.CrossRefPubMed
13.
go back to reference Jang JH, Kim DW, Kim SW, et al.: Allergic rhinitis in laboratory animal workers and its risk factors. Ann Allergy Asthma Immunol 2009, 102:373–377.CrossRefPubMed Jang JH, Kim DW, Kim SW, et al.: Allergic rhinitis in laboratory animal workers and its risk factors. Ann Allergy Asthma Immunol 2009, 102:373–377.CrossRefPubMed
14.
go back to reference Skjold T, Dahl R, Juhl B, Sigsgaard T: The incidence of respiratory symptoms and sensitisation in baker apprentices. Eur Respir J 2008, 32:452–459.CrossRefPubMed Skjold T, Dahl R, Juhl B, Sigsgaard T: The incidence of respiratory symptoms and sensitisation in baker apprentices. Eur Respir J 2008, 32:452–459.CrossRefPubMed
15.
go back to reference Bittner C, Grassau B, Frenzel K, Baur X: Identification of wheat gliadins as an allergen family related to baker’s asthma. J Allergy Clin Immunol 2008, 121:744–749.CrossRefPubMed Bittner C, Grassau B, Frenzel K, Baur X: Identification of wheat gliadins as an allergen family related to baker’s asthma. J Allergy Clin Immunol 2008, 121:744–749.CrossRefPubMed
16.
go back to reference Gill BV, Rice TR, Cartier A, et al.: Identification of crab proteins that elicit IgE reactivity in snow crab-processing workers. J Allergy Clin Immunol 2009, 124:1055–1061.CrossRefPubMed Gill BV, Rice TR, Cartier A, et al.: Identification of crab proteins that elicit IgE reactivity in snow crab-processing workers. J Allergy Clin Immunol 2009, 124:1055–1061.CrossRefPubMed
17.
go back to reference Rondon C, Fernandez J, Lopez S, et al.: Nasal inflammatory mediators and specific IgE production after nasal challenge with grass pollen in local allergic rhinitis. J Allergy Clin Immunol 2009, 124:1005–1011.CrossRefPubMed Rondon C, Fernandez J, Lopez S, et al.: Nasal inflammatory mediators and specific IgE production after nasal challenge with grass pollen in local allergic rhinitis. J Allergy Clin Immunol 2009, 124:1005–1011.CrossRefPubMed
18.
go back to reference James LK, Durham SR: Rhinitis with negative skin tests and absent serum allergen-specific IgE: more evidence for local IgE? J Allergy Clin Immunol 2009, 124:1012–1013.CrossRefPubMed James LK, Durham SR: Rhinitis with negative skin tests and absent serum allergen-specific IgE: more evidence for local IgE? J Allergy Clin Immunol 2009, 124:1012–1013.CrossRefPubMed
19.
go back to reference van Kampen V, Rabstein S, Sander I, et al.: Prediction of challenge test results by flour-specific IgE and skin prick test in symptomatic bakers. Allergy 2008, 63:897–902.CrossRefPubMed van Kampen V, Rabstein S, Sander I, et al.: Prediction of challenge test results by flour-specific IgE and skin prick test in symptomatic bakers. Allergy 2008, 63:897–902.CrossRefPubMed
20.
go back to reference • Johnson VJ, Yucesoy B, Reynolds JS, et al.: Inhalation of toluene diisocyanate vapor induces allergic rhinitis in mice. J Immunol 2007, 179:1864–1871. This was a very well-conducted animal study showing allergic rhinitis features in mice exposed to diisocyanates.PubMed • Johnson VJ, Yucesoy B, Reynolds JS, et al.: Inhalation of toluene diisocyanate vapor induces allergic rhinitis in mice. J Immunol 2007, 179:1864–1871. This was a very well-conducted animal study showing allergic rhinitis features in mice exposed to diisocyanates.PubMed
21.
go back to reference Vanoirbeek JA, De Vooght V, Vanhooren HM, et al.: How long do the systemic and ventilatory responses to toluene diisocyanate persist in dermally sensitized mice? J Allergy Clin Immunol 2008, 121:456–463.CrossRefPubMed Vanoirbeek JA, De Vooght V, Vanhooren HM, et al.: How long do the systemic and ventilatory responses to toluene diisocyanate persist in dermally sensitized mice? J Allergy Clin Immunol 2008, 121:456–463.CrossRefPubMed
22.
go back to reference Hur GY, Sheen SS, Kang YM, et al.: Histamine release and inflammatory cell infiltration in airway mucosa in methylene diphenyl diisocyanate (MDI)-induced occupational asthma. J Clin Immunol 2008, 28:571–580.CrossRefPubMed Hur GY, Sheen SS, Kang YM, et al.: Histamine release and inflammatory cell infiltration in airway mucosa in methylene diphenyl diisocyanate (MDI)-induced occupational asthma. J Clin Immunol 2008, 28:571–580.CrossRefPubMed
23.
go back to reference Kaukiainen A, Martikainen R, Riala R, et al.: Work tasks, chemical exposure and respiratory health in construction painting. Am J Ind Med 2008, 51:1–8.CrossRefPubMed Kaukiainen A, Martikainen R, Riala R, et al.: Work tasks, chemical exposure and respiratory health in construction painting. Am J Ind Med 2008, 51:1–8.CrossRefPubMed
24.
go back to reference van Rooy FG, Houba R, Palmen N, et al.: A cross-sectional study among detergent workers exposed to liquid detergent enzymes. Occup Environ Med 2009, 66:759–765.CrossRefPubMed van Rooy FG, Houba R, Palmen N, et al.: A cross-sectional study among detergent workers exposed to liquid detergent enzymes. Occup Environ Med 2009, 66:759–765.CrossRefPubMed
25.
go back to reference Park DU, Jin KW, Koh DH, et al.: A survey for rhinitis in an automotive ring manufacturing plant. Ind Health 2008, 46:397–403.CrossRefPubMed Park DU, Jin KW, Koh DH, et al.: A survey for rhinitis in an automotive ring manufacturing plant. Ind Health 2008, 46:397–403.CrossRefPubMed
26.
go back to reference Slager RE, Poole JA, LeVan TD, et al.: Rhinitis associated with pesticide exposure among commercial pesticide applicators in the Agricultural Health Study. Occup Environ Med 2009, 66:718–724.CrossRefPubMed Slager RE, Poole JA, LeVan TD, et al.: Rhinitis associated with pesticide exposure among commercial pesticide applicators in the Agricultural Health Study. Occup Environ Med 2009, 66:718–724.CrossRefPubMed
27.
go back to reference Wiszniewska M, Walusiak-Skorupa J, Pannenko I, et al.: Occupational exposure and sensitization to fungi among museum workers. Occup Med (Lond) 2009, 59:237–242.CrossRef Wiszniewska M, Walusiak-Skorupa J, Pannenko I, et al.: Occupational exposure and sensitization to fungi among museum workers. Occup Med (Lond) 2009, 59:237–242.CrossRef
28.
go back to reference Karvala K, Nordman H, Luukkonen R, et al.: Occupational rhinitis in damp and moldy workplaces. Am J Rhinol 2008, 22:457–462.CrossRefPubMed Karvala K, Nordman H, Luukkonen R, et al.: Occupational rhinitis in damp and moldy workplaces. Am J Rhinol 2008, 22:457–462.CrossRefPubMed
29.
go back to reference Seed MJ, Gittins M, DeVocht F, Agius RM: Occupational rhinitis and occupational asthma; one airway two diseases? J Phys Conf Series 2009, 151:012065.CrossRef Seed MJ, Gittins M, DeVocht F, Agius RM: Occupational rhinitis and occupational asthma; one airway two diseases? J Phys Conf Series 2009, 151:012065.CrossRef
30.
go back to reference Airaksinen LK, Tuomi TO, Tuppurainen MO, et al.: Inhalation challenge test in the diagnosis of occupational rhinitis. Am J Rhinol 2008, 22:38–46.CrossRefPubMed Airaksinen LK, Tuomi TO, Tuppurainen MO, et al.: Inhalation challenge test in the diagnosis of occupational rhinitis. Am J Rhinol 2008, 22:38–46.CrossRefPubMed
31.
go back to reference Seed MJ, Carder M, Gittins M, Agius RM: Do all occupational respiratory sensitisers follow the united airways disease model? Thorax 2009, 64:642–643.CrossRefPubMed Seed MJ, Carder M, Gittins M, Agius RM: Do all occupational respiratory sensitisers follow the united airways disease model? Thorax 2009, 64:642–643.CrossRefPubMed
32.
go back to reference Castano R, Theriault G, Maghni K, et al.: Reproducibility of nasal lavage in the context of the inhalation challenge investigation of occupational rhinitis. Am J Rhinol 2008, 22:271–275.CrossRefPubMed Castano R, Theriault G, Maghni K, et al.: Reproducibility of nasal lavage in the context of the inhalation challenge investigation of occupational rhinitis. Am J Rhinol 2008, 22:271–275.CrossRefPubMed
33.
go back to reference Pignatti P, Pala G, Pisati M, et al.: Nasal blown secretion evaluation in specific occupational nasal challenges. Int Arch Occup Environ Health 2009 Aug 23 (Epub ahead of print). Pignatti P, Pala G, Pisati M, et al.: Nasal blown secretion evaluation in specific occupational nasal challenges. Int Arch Occup Environ Health 2009 Aug 23 (Epub ahead of print).
34.
go back to reference Kuolee R, Zhou H, Harris G, et al.: Inhibition of airway eosinophilia and pulmonary pathology in a mouse model of allergic asthma by the live vaccine strain of Francisella tularensis. Clin Exp Allergy 2008, 38:1003–1015.CrossRefPubMed Kuolee R, Zhou H, Harris G, et al.: Inhibition of airway eosinophilia and pulmonary pathology in a mouse model of allergic asthma by the live vaccine strain of Francisella tularensis. Clin Exp Allergy 2008, 38:1003–1015.CrossRefPubMed
35.
go back to reference Airaksinen LK, Luukkonen RA, Lindstrom I, et al.: Long-term exposure and health-related quality of life among patients with occupational rhinitis. J Occup Environ Med 2009, 51:1288–1297.CrossRefPubMed Airaksinen LK, Luukkonen RA, Lindstrom I, et al.: Long-term exposure and health-related quality of life among patients with occupational rhinitis. J Occup Environ Med 2009, 51:1288–1297.CrossRefPubMed
36.
go back to reference Toren K, Blanc P: Asthma caused by occupational exposures is common—a systematic analysis of estimates of the population-attributable fraction. BMC Pulm Med 2009, 9:7.CrossRefPubMed Toren K, Blanc P: Asthma caused by occupational exposures is common—a systematic analysis of estimates of the population-attributable fraction. BMC Pulm Med 2009, 9:7.CrossRefPubMed
37.
go back to reference Bakerly N, Moore V, Vellore A, et al.: Fifteen-year trends in occupational asthma: data from the Shield surveillance scheme. Occup Med (Lond) 2008, 58:169–174.CrossRef Bakerly N, Moore V, Vellore A, et al.: Fifteen-year trends in occupational asthma: data from the Shield surveillance scheme. Occup Med (Lond) 2008, 58:169–174.CrossRef
38.
go back to reference Vandenplas O, Larbanois A, Vanassche F, et al.: Latex-induced occupational asthma: time trend in incidence and relationship with hospital glove policies. Allergy 2009, 64:415–420.CrossRefPubMed Vandenplas O, Larbanois A, Vanassche F, et al.: Latex-induced occupational asthma: time trend in incidence and relationship with hospital glove policies. Allergy 2009, 64:415–420.CrossRefPubMed
39.
go back to reference Folletti I, Forcina A, Marabini A, et al.: Have the prevalence and incidence of occupational asthma and rhinitis because of laboratory animals declined in the last 25 years? Allergy 2008, 63:834–841.CrossRefPubMed Folletti I, Forcina A, Marabini A, et al.: Have the prevalence and incidence of occupational asthma and rhinitis because of laboratory animals declined in the last 25 years? Allergy 2008, 63:834–841.CrossRefPubMed
40.
go back to reference Demir A, Joseph L, Becklake M: Work-related asthma in Montreal, Quebec: population attributable risk in a community-based study. Can Respir J 2008, 15:406–412.PubMed Demir A, Joseph L, Becklake M: Work-related asthma in Montreal, Quebec: population attributable risk in a community-based study. Can Respir J 2008, 15:406–412.PubMed
41.
go back to reference Dragos M, Jones M, Malo JL, et al.: Specific antibodies to diisocyanate and work-related respiratory symptoms in apprentice car-painters. Occup Environ Med 2009, 66:227–234.CrossRefPubMed Dragos M, Jones M, Malo JL, et al.: Specific antibodies to diisocyanate and work-related respiratory symptoms in apprentice car-painters. Occup Environ Med 2009, 66:227–234.CrossRefPubMed
42.
go back to reference Hur GY, Koh DH, Kim HA, et al.: Prevalence of work-related symptoms and serum-specific antibodies to wheat flour in exposed workers in the bakery industry. Respir Med 2008, 102:548–555.CrossRefPubMed Hur GY, Koh DH, Kim HA, et al.: Prevalence of work-related symptoms and serum-specific antibodies to wheat flour in exposed workers in the bakery industry. Respir Med 2008, 102:548–555.CrossRefPubMed
43.
go back to reference Obadia M, Liss G, Lou W, et al.: Relationships between asthma and work exposures among non-domestic cleaners in Ontario. Am J Ind Med 2009, 52:716–723.CrossRefPubMed Obadia M, Liss G, Lou W, et al.: Relationships between asthma and work exposures among non-domestic cleaners in Ontario. Am J Ind Med 2009, 52:716–723.CrossRefPubMed
44.
go back to reference Arif A, Delclos G, Serra C: Occupational exposures and asthma among nursing professionals. Occup Environ Med 2009, 66:274–278.CrossRefPubMed Arif A, Delclos G, Serra C: Occupational exposures and asthma among nursing professionals. Occup Environ Med 2009, 66:274–278.CrossRefPubMed
45.
go back to reference Suarthana E, Malo JL, Heederik D, et al.: Which tools best predict the incidence of work-related sensitisation and symptoms. Occup Environ Med 2009, 66:111–117.CrossRefPubMed Suarthana E, Malo JL, Heederik D, et al.: Which tools best predict the incidence of work-related sensitisation and symptoms. Occup Environ Med 2009, 66:111–117.CrossRefPubMed
46.
go back to reference Suarthana E, Heederik D, Ghezzo H, et al.: Risks for the development of outcomes related to occupational allergies: an application of the asthma-specific job exposure matrix compared with self-reports and investigator scores on job-training-related exposure. Occup Environ Med 2009, 66:256–263.CrossRefPubMed Suarthana E, Heederik D, Ghezzo H, et al.: Risks for the development of outcomes related to occupational allergies: an application of the asthma-specific job exposure matrix compared with self-reports and investigator scores on job-training-related exposure. Occup Environ Med 2009, 66:256–263.CrossRefPubMed
47.
go back to reference •• Gautrin D, Ghezzo H, Infante-Rivard C, et al.: Long-term outcomes in a prospective cohort of apprentices exposed to high-molecular-weight Agents. Am J Respir Crit Care Med 2008, 177:871–879. This is the most extensive and longest study on incidence and risk factors for OA in a cohort of apprentices currently working and exposed to animal-derived allergens.CrossRefPubMed •• Gautrin D, Ghezzo H, Infante-Rivard C, et al.: Long-term outcomes in a prospective cohort of apprentices exposed to high-molecular-weight Agents. Am J Respir Crit Care Med 2008, 177:871–879. This is the most extensive and longest study on incidence and risk factors for OA in a cohort of apprentices currently working and exposed to animal-derived allergens.CrossRefPubMed
48.
go back to reference •• Fishwick D, Barber C, Bradshaw L, et al.: Standards of care for occupational asthma. Thorax 2008, 63:240–250. These are the British Thoracic Society consensus guidelines on the standards of care for asthma in the workplace.CrossRefPubMed •• Fishwick D, Barber C, Bradshaw L, et al.: Standards of care for occupational asthma. Thorax 2008, 63:240–250. These are the British Thoracic Society consensus guidelines on the standards of care for asthma in the workplace.CrossRefPubMed
49.
go back to reference Sauni R, Kauppi P, Helaskoski E, et al.: Audit of quality of diagnostic procedures for occupational asthma. Occup Med (Lond) 2009, 59:230–236.CrossRef Sauni R, Kauppi P, Helaskoski E, et al.: Audit of quality of diagnostic procedures for occupational asthma. Occup Med (Lond) 2009, 59:230–236.CrossRef
50.
go back to reference Park D, Moore V, Burge C, et al.: Serial PEF measurement is superior to cross-shift change in diagnosing occupational asthma. Eur Respir J 2009, 34:574–578.CrossRefPubMed Park D, Moore V, Burge C, et al.: Serial PEF measurement is superior to cross-shift change in diagnosing occupational asthma. Eur Respir J 2009, 34:574–578.CrossRefPubMed
51.
go back to reference Moore V, Jaakkola M, Burge C, et al.: PEF analysis requiring shorter records for occupational asthma diagnosis. Occup Med 2009, 59:413–417.CrossRef Moore V, Jaakkola M, Burge C, et al.: PEF analysis requiring shorter records for occupational asthma diagnosis. Occup Med 2009, 59:413–417.CrossRef
52.
go back to reference Hur G, Koh D, Choi G, et al.: Clinical and immunologic findings of methylene diphenyl diisocyanate-induced occupational asthma in a car upholstery factory. Clin Exp Allergy 2008, 38:586–593.CrossRefPubMed Hur G, Koh D, Choi G, et al.: Clinical and immunologic findings of methylene diphenyl diisocyanate-induced occupational asthma in a car upholstery factory. Clin Exp Allergy 2008, 38:586–593.CrossRefPubMed
53.
go back to reference Quirce S, Lemiere C, de Blay F, et al.: Noninvasive methods for assessment of airway inflammation in occupational settings. Allergy 2009 Dec 3 (Epub ahead of print). Quirce S, Lemiere C, de Blay F, et al.: Noninvasive methods for assessment of airway inflammation in occupational settings. Allergy 2009 Dec 3 (Epub ahead of print).
54.
go back to reference Quint J, Beckett WS, Campleman SL, et al.: Primary prevention of occupational asthma: identifying and controlling exposures to asthma-causing agents. Am J Ind Med 2008, 51:477–491.CrossRefPubMed Quint J, Beckett WS, Campleman SL, et al.: Primary prevention of occupational asthma: identifying and controlling exposures to asthma-causing agents. Am J Ind Med 2008, 51:477–491.CrossRefPubMed
55.
go back to reference Heederik D, van Rooy F: Exposure assessment should be integrated in studies on the prevention and management of occupational asthma. Occup Environ Med 2008, 65:149–150.CrossRefPubMed Heederik D, van Rooy F: Exposure assessment should be integrated in studies on the prevention and management of occupational asthma. Occup Environ Med 2008, 65:149–150.CrossRefPubMed
56.
go back to reference Nienhaus A, Kromark K, Raulf-Heimsoth M, et al.: Outcome of occupational latex allergy—work ability and quality of life. PLoS One 2008, 3:e3459.CrossRefPubMed Nienhaus A, Kromark K, Raulf-Heimsoth M, et al.: Outcome of occupational latex allergy—work ability and quality of life. PLoS One 2008, 3:e3459.CrossRefPubMed
57.
go back to reference Lavoie KL, Joseph M, Bacon SL: Psychological distress and occupational asthma. Curr Opin Allergy Clin Immunol 2009, 9:103–109.CrossRefPubMed Lavoie KL, Joseph M, Bacon SL: Psychological distress and occupational asthma. Curr Opin Allergy Clin Immunol 2009, 9:103–109.CrossRefPubMed
58.
go back to reference Malo JL, L’archeveque J, Ghezzo H: Direct costs of occupational asthma in Quebec between 1988 and 2002. Can Respir J 2008, 15:413–416.PubMed Malo JL, L’archeveque J, Ghezzo H: Direct costs of occupational asthma in Quebec between 1988 and 2002. Can Respir J 2008, 15:413–416.PubMed
59.
go back to reference • Malo JL, L'archeveque J, Castellanos L, et al.: Long-term outcomes of acute irritant-induced asthma. Am J Respir Crit Care Med 2009, 179:923–928. This was the longest follow-up of patients affected by RADS.CrossRefPubMed • Malo JL, L'archeveque J, Castellanos L, et al.: Long-term outcomes of acute irritant-induced asthma. Am J Respir Crit Care Med 2009, 179:923–928. This was the longest follow-up of patients affected by RADS.CrossRefPubMed
60.
go back to reference Takeda N, Maghni K, Daigle S, et al.: Long-term pathologic consequences of acute irritant-induced asthma. J Allergy Clin Immunol 2009, 124:975–981.CrossRefPubMed Takeda N, Maghni K, Daigle S, et al.: Long-term pathologic consequences of acute irritant-induced asthma. J Allergy Clin Immunol 2009, 124:975–981.CrossRefPubMed
Metadata
Title
Occupational Rhinitis and Asthma: Where Do We Stand, Where Do We Go?
Authors
Roberto Castano
Jean-Luc Malo
Publication date
01-03-2010
Publisher
Current Science Inc.
Published in
Current Allergy and Asthma Reports / Issue 2/2010
Print ISSN: 1529-7322
Electronic ISSN: 1534-6315
DOI
https://doi.org/10.1007/s11882-010-0092-4

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