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BMC Public Health
Published in: BMC Public Health 1/2022

Open Access 01-12-2022 | Obesity | Research

Obesity indicators as mediators of association between daytime napping and type 2 diabetes mellitus: the Guangzhou Biobank Cohort Study

Authors: Jing Yi Xiao, Wei Sen Zhang, Chao Qiang Jiang, Ya Li Jin, Feng Zhu, Kar Keung Cheng, Tai Hing Lam, Lin Xu

Published in: BMC Public Health | Issue 1/2022

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Abstract

Objective

To examine the mediating effect of obesity indicators on the association between daytime napping and type 2 diabetes mellitus (T2DM) qualitatively and quantitatively using baseline data from the Guangzhou Biobank Cohort Study.

Methods

Twenty-nine thousand three hundred fifty-five participants aged 50+ years were included in this cross-sectional study. Mediation analysis was used to assess the mediating effect of body mass index (BMI), waist circumference (WC), hip circumference (HC), waist-to-hip ratio (WHR) and waist-to-height ratio (WHtR) on the association between daytime napping and T2DM after adjustment for sex, age, education, occupation, smoking status, alcohol use and physical activity.

Results

The mean (standard deviation) age of participants was 61.5 ( 7.1) years. The prevalence of T2DM and daytime napping was 12.5% and 65.2%, respectively. After adjustment for potential confounders, WC, WHR and WHtR showed partial mediating effects on the association between daytime napping and T2DM, with the proportion (95% confidence interval) of mediation effect being 10.17% (8.14–14.43%), 14.91% (11.95–21.24%) and 9.36% (7.49–13.29%), respectively. No mediating effect of BMI or HC on the association between daytime napping and T2DM was found.

Conclusions

Our results showed significant mediating effects of WC, WHR and WHtR on the association between daytime napping and T2DM, suggesting that waist circumference management could be important in daytime nappers.
Appendix
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Metadata
Title
Obesity indicators as mediators of association between daytime napping and type 2 diabetes mellitus: the Guangzhou Biobank Cohort Study
Authors
Jing Yi Xiao
Wei Sen Zhang
Chao Qiang Jiang
Ya Li Jin
Feng Zhu
Kar Keung Cheng
Tai Hing Lam
Lin Xu
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2022
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-021-12451-8

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