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Open Access 01-12-2021 | Obesity | Research article

Influence of weight status on bone mineral content measured by DXA in children

Authors: Francisco Sánchez Ferrer, Ernesto Cortes Castell, Francisco Carratalá Marco, Mercedes Juste Ruiz, José Antonio Quesada Rico, Ana Pilar Nso Roca

Published in: BMC Pediatrics | Issue 1/2021

Abstract

Introduction

Childhood obesity is a public health problem with repercussions in later life. As tissue formation peaks in childhood we determined how weight status influences bone mineral content.

Material and methods

We studied 553 children aged 4–18 years over 10 years (46.8% girls). We measured age, weight, height and through bone densitometry (DXA), bone mineral content (BMC), bone mineral density (BMD), and waist, arm and hip circumferences. The patients were divided into groups using the body mass index z-score: underweight, normal weight, overweight, obese and very obese.

Results

BMC and BMD values were highest in the normal-weight and overweight groups. Logistic regression showed bone mineralization was inversely associated with waist circumference, the association being positive for weight and age. No differences were found according to sex.

Discussion

Studies of the relationship between weight and bone mineralization report contradictory results, often because of different study designs. Moreover, studies in children are either few or with small samples. Our findings in a large sample show the importance of weight status in bone mineralization given the risk of bone fractures or osteoporosis.

Conclusions

Weight status influenced bone mineralization. BMC and BMD decreased in children with a higher degree of obesity. Waist circumference correlated negatively with bone mineralization.

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Title: Influence of weight status on bone mineral content measured by DXA in children
Authors: Francisco Sánchez Ferrer
Ernesto Cortes Castell
Francisco Carratalá Marco
Mercedes Juste Ruiz
José Antonio Quesada Rico
Ana Pilar Nso Roca
Publication date: 01-12-2021
Publisher: BioMed Central
Keywords: Obesity
Obesity
Underweight
Osteoporosis
Underweight
Osteoporosis
Overweight
Published in: BMC Pediatrics / Issue 1/2021
Electronic ISSN: 1471-2431
DOI: https://doi.org/10.1186/s12887-021-02665-5

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Springer Medicine

Influence of weight status on bone mineral content measured by DXA in children

Abstract

Introduction

Material and methods

Results

Discussion

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Material and methods

Results

Discussion

Conclusions

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