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01-05-2020 | Obesity | Review

Efficacy and Safety of Endoscopic Sleeve Gastroplasty at Mid Term in the Management of Overweight and Obese Patients: a Systematic Review and Meta-Analysis

Authors: Antonio Afonso de Miranda Neto, Diogo Turiani Hourneaux de Moura, Igor Braga Ribeiro, Ahmad Khan, Shailendra Singh, Alberto Machado da Ponte Neto, Antonio Coutinho Madruga Neto, Epifanio Silvino do Monte Junior, Francisco Tustumi, Wanderley Marques Bernardo, Eduardo Guimarães Hourneaux de Moura

Published in: Obesity Surgery | Issue 5/2020

Abstract

Background

Endoscopic sleeve gastroplasty (ESG) has emerged as a promising technique in endoscopic bariatric and metabolic therapies (EBMTs). We aimed to perform a systematic review and meta-analysis to provide an update on its efficacy and safety.

Methods

This is a systematic review and meta-analysis was performed following the PRISMA guidelines. MEDLINE, Cochrane, EMBASE, and LILACS were searched to identify the studies related to ESG.

Results

Eleven studies with a total of 2170 patients were included. The average BMI pre-ESG was 35.78 kg/m². Pooled mean %TWL observed at 6, 12, and 18 months was 15.3%, 16.1%, and 16.8% respectively. Pooled mean %EWL at 6, 12, and 18 months was 55.8%, 60%, and 73% respectively. No procedure-related mortality was reported.

Conclusion

ESG is a safe and effective procedure for primary obesity therapy with promising short- and mid-term results.

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Title: Efficacy and Safety of Endoscopic Sleeve Gastroplasty at Mid Term in the Management of Overweight and Obese Patients: a Systematic Review and Meta-Analysis
Authors: Antonio Afonso de Miranda Neto
Diogo Turiani Hourneaux de Moura
Igor Braga Ribeiro
Ahmad Khan
Shailendra Singh
Alberto Machado da Ponte Neto
Antonio Coutinho Madruga Neto
Epifanio Silvino do Monte Junior
Francisco Tustumi
Wanderley Marques Bernardo
Eduardo Guimarães Hourneaux de Moura
Publication date: 01-05-2020
Publisher: Springer US
Keywords: Obesity
Obesity
Overweight
Published in: Obesity Surgery / Issue 5/2020
Print ISSN: 0960-8923
Electronic ISSN: 1708-0428
DOI: https://doi.org/10.1007/s11695-020-04449-9

At a glance: The STEP trials

Springer Medicine

Efficacy and Safety of Endoscopic Sleeve Gastroplasty at Mid Term in the Management of Overweight and Obese Patients: a Systematic Review and Meta-Analysis

Abstract

Background

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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