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Open Access 01-12-2021 | Obesity | Original Research Article

Effects of Non-periodized and Linear Periodized Combined Exercise Training on Insulin Resistance Indicators in Adults with Obesity: A Randomized Controlled Trial

Authors: Anne Ribeiro Streb, Larissa dos Santos Leonel, Rodrigo Sudatti Delevatti, Cláudia Regina Cavaglieri, Giovani Firpo Del Duca

Published in: Sports Medicine - Open | Issue 1/2021

Abstract

Background

The aim was to verify the effect of non-periodized and linear periodized combined (aerobic plus resistance) exercise training on insulin resistance markers in adults with obesity.

Methods

A blinded randomized control trial was conducted with three groups of individuals with obesity (BMI, 30–39.9 kg/m²): control group (CG, n = 23), non-periodized group (NG, n = 23), and linear periodized group (PG, n = 23). The NG and PG performed aerobic and resistance exercises in the same session in aerobic-resistance order for 16 weeks. Both intervention groups trained three sessions weekly, with a total duration of 60 min each. The aerobic training of the NG had a duration of 30 min always between 50% and 59% of the reserve heart rate (HRres), while resistance exercise was comprised of 6 exercises, performed always in 2 × 10–12 maximum repetitions (MRs). The PG progressed the aerobic and resistance training from 40%–49% to 60%–69% (HRres) and from 2 × 12–14 to 2 × 8–10 RM, respectively, along the intervention period. The evaluated indicators of insulin resistance included fasting glucose, fasting insulin, and homeostasis model assessment-estimated insulin resistance (HOMA-IR) collected pre- and post-intervention. The analyses to verify the exercise training effect were performed using generalized estimating equations.

Results

After 16 weeks of training, per protocol analysis (n = 39) showed significant reductions in HOMA-IR only in the training groups (NG: Δ = − 1.6, PG: Δ = − 0.6; p = 0.094). Intention-to-treat analysis demonstrated significant reductions in fasting insulin levels (NG: Δ = − 1.4, PG: Δ = − 1.0; p = 0.004) and HOMA-IR (NG: Δ = − 5.5, PG: Δ = − 3.8; p = 0.002).

Conclusion

Periodized and non-periodized combined exercise training similarly reduces insulin resistance markers in adults with obesity.

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Title: Effects of Non-periodized and Linear Periodized Combined Exercise Training on Insulin Resistance Indicators in Adults with Obesity: A Randomized Controlled Trial
Authors: Anne Ribeiro Streb
Larissa dos Santos Leonel
Rodrigo Sudatti Delevatti
Cláudia Regina Cavaglieri
Giovani Firpo Del Duca
Publication date: 01-12-2021
Publisher: Springer International Publishing
Keywords: Obesity
Obesity
Insulins
Insulins
Published in: Sports Medicine - Open / Issue 1/2021
Print ISSN: 2199-1170
Electronic ISSN: 2198-9761
DOI: https://doi.org/10.1186/s40798-021-00359-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Effects of Non-periodized and Linear Periodized Combined Exercise Training on Insulin Resistance Indicators in Adults with Obesity: A Randomized Controlled Trial

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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