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BMC Endocrine Disorders
Published in: BMC Endocrine Disorders 1/2023

Open Access 01-12-2023 | Obesity | Research

Effect of mastication evaluation and intervention on body composition and biochemical indices in female patients with obesity: a randomized controlled trial

Authors: Nagisa Hidaka, Satoshi Kurose, Nana Takao, Takumi Miyauchi, Sachiko Nakajima, Sawako Yoshiuchi, Aya Fujii, Kazuhisa Takahashi, Hiromi Tsutsumi, Daiki Habu, Kazuhiro Taniguchi, Yutaka Kimura

Published in: BMC Endocrine Disorders | Issue 1/2023

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Abstract

Background

A limited number of studies have evaluated the masticatory indices of individuals with obesity who only chew their food a few times and for shorter duration or who were provided with an instructional intervention. This study aimed to examine the effects of a 6-month instructional mastication intervention on the body composition and biochemical indices in female patients with obesity.

Methods

Female patients with obesity were randomly classified into a conventional treatment group (CTG; 12 individuals), which only received normal nutritional and exercise guidance, and a mastication intervention group (MIG; 16 individuals), which received an additional mastication guidance. The MIG received guidance on foods requiring increased number of chews and chewing duration, eating techniques, and the proper method of cutting foods.

Results

Changes in the masticatory, body composition, and biochemical indices were compared before and after the 6-month intervention. The values of body composition indices decreased significantly in both groups; however, the rate of change in body mass index significantly decreased in the MIG. In addition, the values of biochemical indices were significantly decreased in the MIG compared with that in the CTG, which is attributed to the addition of mastication instruction to female patients with obesity.

Conclusion

Increasing the number of chews and duration of chewing times for carbohydrates, which are staple foods, possibly contributed to weight loss and improvement of glucose metabolism.

Trial registration

UMIN, UMIN000025875. Registered on 27 Jan 2017.
Literature
1.
Yatsuya H, Toyoshima H, Yamagishi K, Tamakoshi K, Taguri M, Harada A, et al. Body mass index and risk of stroke and myocardial infarction in a relatively lean population: meta-analysis of 16 japanese cohorts using individual data. Circ Cardiovasc Qual Outcomes. 2010;3:498–505.CrossRefPubMed
2.
Louise C, Katy T. Reasons for eating “unhealthy” snacks in overweight and obese males and females. J Hum Nutr Diet. 2014;27:333–41.CrossRef
3.
Christen AG, Christen JA. Horace Fletcher (1849–1919): “the great masticator. J Hist Dent. 1997;45:95–100.PubMed
4.
Yamane M, Ekuni D, Mizutani S, Kataoka K, Sakumoto-Kataoka M, Kawabata Y, et al. Relationships between eating quickly and weight gain in japanese university students: a longitudinal study. Obesity. 2014;22:2262–6.CrossRefPubMed
5.
Smit HJ, Kemsley EK, Tapp HS, Henry CJK. Does prolonged chewing reduce food intake? Fletcherism revisited. Appetite. 2011;57:295–8.CrossRefPubMed
6.
Hamada Y, Miyaji A, Hayashi N. Effect of postprandial gum chewing on diet-induced thermogenesis. Obesity. 2016;24:878–85.CrossRefPubMed
7.
Otsuka R, Tamakoshi K, Yatsuya H, Murata C, Sekiya A, Wada K, et al. Eating fast leads to obesity: findings based on self-administered questionnaires among middle-aged japanese men and women. J Epidemiol. 2006;16:117–24.CrossRefPubMedPubMedCentral
8.
Ekuni D, Furuta M, Tomofuji T, Irie K, Azuma T, Iwasaki Y, et al. Effects of eating behaviors on being overweight in japanese university students: a cross-sectional survey at the Okayama University. Asia Pac J Public Health. 2013;25:326–34.CrossRefPubMed
9.
Kimura Y, Nanri A, Matsushita Y, Sasaki S, Mizoue T. Eating behavior in relation to prevalence of overweight among japanese men. Asia Pac J Clin Nutr. 2011;20:29–34.PubMed
10.
Li J, Zhang N, Hu L, Li Z, Li R, Li C, et al. Improvement in chewing activity reduces energy intake in one meal and modulates plasma gut hormone concentrations in obese and lean young chinese men. Am J Clin Nutr. 2011;94:709–16.CrossRefPubMed
11.
Hidaka N, Kurose S, Takao N, Miyauchi T, Nakajima S, Yoshiuchi S, et al. Masticatory behaviors and gender differences in people with obesity as measured via an earphone-style light-sensor-based mastication meter. Nutrients. 2022;14:2990.CrossRefPubMedPubMedCentral
12.
Taniguchi K, Kondo H, Tanaka T, Nishikawa A, Earable RCC. Development of an earphone-type reliable chewing-count measurement device. J Healthc Eng. 2018;2018:6161525.CrossRefPubMedPubMedCentral
13.
Shikany JM, Thomas AS, McCubrey RO, Beasley TM, Allison DB. Randomized controlled trial of chewing gum for weight loss. Obesity. 2012;20:547–52.CrossRefPubMed
14.
Zhu Y, Hsu WH, Hollis JH. Increased number of chews during a fixed-amount meal suppresses postprandial appetite and modulates glycemic response in older males. Physiol Behav. 2014;133:136–40.CrossRefPubMed
15.
Suzuki H, Fukushima M, Okamoto S, Takahashi O, Shimbo T, Kurose T, et al. Effect of thorough mastication on postprandial plasma glucose concentrations in nonobese japanese subjects. Metabolism. 2005;54:1593–9.CrossRefPubMed
16.
Tabarean IV. Histamine receptor signaling in energy homeostasis. Neuropharmacology. 2016;106:13–9.CrossRefPubMed
17.
Sakata T, Yoshimatsu H, Kurokawa M. Hypothalamic neuronal histamine: implications of its homeostatic control of energy metabolism. Nutrition. 1997;13:403–11.CrossRefPubMed
18.
Fujise T, Yoshimatsu H, Kurokawa M, Oohara A, Kang M, Nakata M, et al. Satiation and masticatory function modulated by brain histamine in rats. Proc Soc Exp Biol Med. 1998;217:228–34.CrossRefPubMed
19.
Sonoki K, Iwase M, Takata Y, Nakamoto T, Masaki C, Hosokawa R, et al. Effects of thirty-times chewing per bite on secretion of glucagon-like peptide-1 in healthy volunteers and type 2 diabetic patients. Endocr J. 2013;60(3):311–9.CrossRefPubMed
20.
Parka S, Shinb WS. Differences in eating behaviors and masticatory performances by gender and obesity status. Physiol Behav. 2015;138:69–74.CrossRef
Metadata
Title
Effect of mastication evaluation and intervention on body composition and biochemical indices in female patients with obesity: a randomized controlled trial
Authors
Nagisa Hidaka
Satoshi Kurose
Nana Takao
Takumi Miyauchi
Sachiko Nakajima
Sawako Yoshiuchi
Aya Fujii
Kazuhisa Takahashi
Hiromi Tsutsumi
Daiki Habu
Kazuhiro Taniguchi
Yutaka Kimura
Publication date
01-12-2023
Publisher
BioMed Central
Keywords
Obesity
Obesity
Published in
BMC Endocrine Disorders / Issue 1/2023
Electronic ISSN: 1472-6823
DOI
https://doi.org/10.1186/s12902-023-01379-2

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