Top

European Archives of Paediatric Dentistry

Published in:

01-02-2020 | Obesity | Systematic Review

Association of obesity with the eruption of first and second permanent molars in children: a systematic review

Authors: N. Mohamedhussein, A. Busuttil-Naudi, H. Mohammed, A. UlHaq

Published in: European Archives of Paediatric Dentistry | Issue 1/2020

Abstract

Background

Eruption timing of permanent teeth, particularly first and second molars, is of great importance due to its influence on occlusion, caries risk and timing of preventive and orthodontic intervention.

Aim

To evaluate the evidence assessing the correlation between obesity and eruption time of first and second permanent molars in children under 16 years of age as compared to normal-weight children. A secondary aim was to assess the total number of erupted teeth in both groups.

Methods

A systematic search of databases including PubMed, MEDLINE, EMBASE, Scopus and Web of Science was conducted. Studies that assessed the effect of body mass index (BMI), adjusted BMI or z scores on dental eruption were included. National Institute of Health ‘Quality Assessment Tool for Observational Cohort and Cross-sectional Studies’ was used to assess the quality of included papers. A random-effects model with its 95% confidence intervals (CIs) was considered for meta-analysis.

Results

A total of 381 papers were screened following duplicate removal. Twenty-six papers were read in full text, of which 19 were excluded. Seven studies were included in this review; one was longitudinal, and six were cross-sectional in design. A positive association of dental eruption with obesity was noted in six studies. Two studies were included in the explorative meta-analysis, the results of which indicated that obese, 12-year-olds are likely to have one more erupted tooth than their counterparts with a mean difference (MD) of (0.99, 95% CI 0.628–1.352).

Conclusion

There appears to be a positive correlation between obesity and dental eruption including the eruption timing of first and second permanent molars. Main risk of bias arises from the cross-sectional nature of included studies and lack of control of potential confounders. Further high-quality evidence is required to elucidate this association. Registration PROSPERO (CRD42017084368).

Registration

PROSPERO (CRD42017084368).

Abraham S, Lowenstein FW, Daniel E (1975) Preliminary findings of the first health and nutrition examination survey, United States, 1971–72. Anthropometric and Clinical Findings. 1975. https://www.cdc.gov/nchs/data/nhanes/nhanesi/anthro.pdf. Accessed on 18 Jul 2018.

Agarwal KN, Gupta R, Farida MM, Kalra N. Permanent dentition in Delhi boys of age 5–14 years. Indian Paediatr. 2004;41:1031–5.

Almonaitiene R, Balciuniene I, Tutkuviene J. Factors influencing permanent teeth eruption. Part one—general factors. Stomatologija. Baltic Dental Maxillofac J. 2010;12:67–72.

Billewicz WZ, McGregor IA. Eruption of permanent teeth in west African (Gambian) children in relation to age, sex and physique. Ann Hum Biol. 1975;2:117–28.PubMedCrossRef

Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of US adults. N Engl J Med. 2003;348(17):1625–38.PubMedCrossRef

Carvalho JC. Caries Process on Occlusal Surfaces: evolving Evidence and Understanding. Caries Res. 2014;48:339–46.PubMedCrossRef

Centers for disease control and prevention (2018) Defining childhood obesity. https://www.cdc.gov/obesity/childhood/defining.html. Accessed 21 Mar 2019.

Checklist of items to consider in data collection (2018) Cochrane Training. http://handbook-5-1.cochrane.org/…/table_7_3_a_checklist_of_items_to_consider_in_data_collection.html. Accessed 20 Jul 2018.

Cizza G, Dorn LD, Lotsikas A, Sereika S, Rotenstein D, Chrousos GP. Circulating plasma leptin and IGF- 1 levels in girls with premature adrenarche: potential implications of a preliminary study. Horm Metab Res. 2001;33(3):138–43.PubMedCrossRef

Cobourne MT, Williams A, McMullen R. A guideline for the extraction of first permanent molars in children. 2014. https://www.rcseng.ac.uk/dental-faculties/fds/publications-guidelines/clinical-guidelines/. Accessed 25 May 2019.

Dahiya BR, Singh V, Parveen S, Singh HP, Singh D. Age estimation from eruption of permanent teeth as a tool for growth monitoring. J Indian Acad For Med. 2013;35(2):148–50.

Demirjian A, Goldstein H, Tanner JM. A new system of dental age assessment. Hum Biol. 1973;45(2):211–27.PubMed

Ferreira Zandoná A, Santiago E, Eckert GJ, Katz BP, de Oliveira PS, Capin OR, Mau M, Zero DT. The natural history of dental caries lesions: a 4-year observational study. J Dent Res. 2012;91(9):841–6.PubMedPubMedCentralCrossRef

Haddad AE, Correa MS. The relationship between the number of erupted primary teeth and the child’s height and weight: a cross-sectional study. J Clin Pediatr Dent. 2005;29(4):357–62.PubMedCrossRef

Health survey for England 2016, Children’s Health (2017) https://files.digital.nhs.uk/publication/m/c/hse2016-child-health.pdf. Accessed 18 Jul 2018.

Heinrich-Weltzien R, Zorn C, Monse B, Kromeyer-Hauschild K. Relationship between malnutrition and the number of permanent teeth in Filipino 10- to 13-year-olds. Biomed Res Int. 2013;2013:205950.PubMedPubMedCentralCrossRef

Hernandez M, Boj JR, Sentís J, Duran J, Ustrell JM. Eruption of the permanent teeth in a group of 1.123 catalan children. Pediatr Catal. 2002;62(4):179–84.

Herouvi D, Karanasios E, Karayianni C, Karavanaki K. Cardiovascular disease in childhood: the role of obesity. Eur J Pediatr. 2013;172(6):721–32.PubMedCrossRef

Hilgers KK, Akridge M, Scheetz JP, Kinane DF. Childhood obesity and dental development. Pediatr Dent. 2006;28(1):18–22.PubMed

Jelinek E. The role of certain relevant factors in temporal aberrations of tooth eruption. Acta Stomatol Croatica. 1982;16(1):23–31.

Kaur B, Singh R. Physical growth and age at eruption of deciduous and permanent teeth in well-nourished Indian girls from birth to 20 years. Am J Hum Biol. 1992;4(6):757–66.PubMedCrossRef

Khan N. Eruption time of permanent teeth in Pakistani Children. Iran J Public Health. 2011;40(4):63–73.PubMedPubMedCentral

Kutesa A, Nkamba EM, Muwazi L, Buwembo W, Rwenyonyi CM. Weight, height and eruption times of permanent teeth of children aged 4-15 years in Kampala, Uganda. Oral Health. 2013;16:13–5.

Leung SS. A simple guide to childhood growth and nutrition assessment. Hong Kong: Chinese University of Hong Kong; 1995.

Li W, Liu Q, Deng X, Chen Y, Liu S, Story M. Association between obesity and puberty timing: a systematic review and meta-analysis. Int J Environ Res Public Health. 2017;14(10):1266.PubMedCentralCrossRef

Lysiak-Seichter M, Gredes M, Proff P, Gedrange T, Splieth CH. Evaluation of disparities in physical development and dental age of two specific groups of boys. Eur J Paediatr Dent. 2006;7(4):169–73.PubMed

Mack KB, Phillips C, Jain N, Koroluk LD. Relationship between body mass index percentile and skeletal maturation and dental development in orthodontic patients. AJO-DO. 2013;143(2):228–34.

Manjunatha BS, Soni NK. Estimation of age from development and eruption of teeth. J Forensic Dent Sci. 2014;6(2):73–6.PubMedPubMedCentralCrossRef

Marcovecchio ML, Chiarelli F. Obesity and growth during childhood and puberty. World Rev Nutr Diet. 2013;106:135–41.PubMedCrossRef

McGown C, Birerdinc A, Younossi ZM. Adipose tissue as an endocrine organ. Clin Liver Dis. 2014;18:41e58.CrossRef

Must A, Tybor DJ. Physical activity and sedentary behavior: a review of longitudinal studies of weight and adiposity in youth. Int J Obes. 2005;29(2):S84–96.CrossRef

Must A, Phillips SM, Tybor DJ, Lividini K, Hayes C. The association between childhood obesity and tooth eruption. Obesity. 2012;20(10):2070–4.PubMedCrossRef

Nicholas CL, Thalji G, Richter A. Childhood obesity and accelerated timing of dental development: a critical review. Forensic Anthropol. 2018a;1(3):170–9.CrossRef

Nicholas CL, Kadavy K, Holton NE, Marshall T, Richter A, Southard T. Childhood body mass index is associated with early dental development and eruption in a longitudinal sample from the Iowa Facial Growth Study. AJO-DO. 2018b;154(1):72–81.

Ohrn K, Al-Kahlili B, Huggare J, Forsberg CM, Marcus C, Dahllöf G. Craniofacial morphology in obese adolescents. Acta Odontol Scand. 2002;60(4):193–7.PubMedCrossRef

Pahel BT, Vann WF Jr, Divaris K, Rozier RG. A contemporary examination of first and second permanent molar emergence. J Dent Res. 2017;96(10):1115–21.PubMedPubMedCentralCrossRef

Papadimitriou A, Nicolaidou P, Fretzayas A, Chrousos GP. Clinical review: Constitutional advancement of growth, a.k.a., early growth acceleration, predicts early puberty and childhood obesity. J Clin Endocrinol Metab. 2010;95(10):4535–41.PubMedCrossRef

Polczer J. Relation between the eruption of permanent teeth and body development. Fogorv Sz. 1965;58(11):333–5.PubMed

Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies by NIH, National Heart, Lung and Blood Institute. 2018. https://www.nhlbi.nih.gov/health-topics/study-quality-assessment-tools. Accessed 19 Jul 2018.

Reinehr T, de Sousa G, Wabitsch M. Relationships of IGF-1 and androgens to skeletal maturation in obese children and adolescents. J Pediatr Endocrinol Metab. 2006;19:1133–40.PubMedCrossRef

Sabharwal S, Sengupta S, Sharma B, Singh S, Rastogi V. Correlation of body mass index with eruption time of permanent first molars and incisors and caries occurrence: A cross-sectional study in school children in Uttar Pardesh, India. Eur J Gen Dent. 2013;2(2):114.CrossRef

Sahin F, Camurdan AD, Camurdan MO, Olmez A, Oznurhan F, Beyazova U. Factors affecting the timing of teething in healthy Turkish infants: a prospective cohort study. Int J Paediatr Dent. 2008;18:262–6.PubMedCrossRef

Sánchez-Pérez L, Irigoyen M, Zepeda M. Dental caries, tooth eruption timing and obesity: a longitudinal study in a group of Mexican schoolchildren. Acta Odontol Scand. 2010;6(1):57–64.CrossRef

Satake KU, da Silva RH. Relationship between growth and tooth eruption. Relationship between growth and physical development and eruption of first permanent molars in São Paulo students. RGO. 1990;38(3):183–7.PubMed

Serdula MK, Ivery D, Coates RJ, Freedman DS, Williamson DF, Byers T. Do obese children become obese adults? A review of the literature. Prev Med. 1993;22(2):167–77.PubMedCrossRef

Shaweesh AI, Alsoleihat FD. Association between body mass index and timing of permanent tooth emergence in Jordanian children and adolescents. Int J Stomat Occ Med. 2013;6:50–8.CrossRef

Šindelářová R, Soukup P, Broukal Z. The relationship of obesity to the timing of permanent tooth emergence in Czech children. Acta Odontol Scand. 2018;76(3):220–5.PubMedCrossRef

Smiech-Słomkowska G, Jarnecka B. Physical development and teeth age of children aged 7-10 years. Czas Stomatol. 1990;43(7):434–8.PubMed

Tričković-Janjić O, Apostolović M, Janošević M, Filipović G. Correlation of dental age and anthropometric parametres of the overall growth and development in children. Vojnosanit Pregl. 2008;65(2):146.CrossRef

Triratana T, Hemindra D, Kiatiparjuk C. Eruption of permanent teeth in malnourished children. J Dent. Assoc. Thai. 1990;40:100–8.PubMed

Udovyts’ka OV, Lepors’ka LB. Relation between the time of eruption of the teeth and the physical development of children. Pediatr Akus Ginekol. 1975;5:8–9.

Weisell RC. Body mass index as an indicator of obesity. Asia Pac J Clin Nutr. 2002;11:681–4.CrossRef

Willems G. A review of the most commonly used dental age estimation techniques. J Forensic Odontostomatol. 2001;19(1):9–17.PubMed

Wise GE. Cellular and molecular basis of tooth eruption. Orthod Craniofac Res. 2009;12:67–77.PubMedPubMedCentralCrossRef

Wong HM, Peng SM, Yang Y, King NM, McGrath CP. Tooth eruption and obesity in 12- year- old children. Journal of Dental Sciences. 2017;12(2):126–32.PubMedCrossRef

World Health Organization. Growth reference 5-19 years. https://www.who.int/growthref/who2007_bmi_for_age/en/. Accessed on 21 Mar 2019.

Title: Association of obesity with the eruption of first and second permanent molars in children: a systematic review
Authors: N. Mohamedhussein
A. Busuttil-Naudi
H. Mohammed
A. UlHaq
Publication date: 01-02-2020
Publisher: Springer Berlin Heidelberg
Keywords: Obesity
Obesity
Overweight
Published in: European Archives of Paediatric Dentistry / Issue 1/2020
Print ISSN: 1818-6300
Electronic ISSN: 1996-9805
DOI: https://doi.org/10.1007/s40368-019-00452-6

At a glance: The STEP trials

Springer Medicine

Association of obesity with the eruption of first and second permanent molars in children: a systematic review

Abstract

Background

Aim

Methods

Results

Conclusion

Registration

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Aim

Methods

Results

Conclusion

Registration

Please log in to get access to this content

Other articles of this Issue 1/2020

Feeding practices and early childhood caries among preschool children of Bhubaneswar, India

Reaction times of children having nitrous oxide inhalation sedation for dental procedures

Oral health in children with acute lymphoblastic leukaemia: before and after chemotherapy treatment

Comparative evaluation of the effects of human breast milk and plain and probiotic-containing infant formulas on enamel mineral content in primary teeth: an in vitro study

Effects of several storage media on viability and proliferation capacity of periodontal ligament cells

Children’s perceptions regarding functional limitations due to oral problems