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Published in: International Urology and Nephrology 1/2013

01-02-2013 | Urology - Original Paper

Obesity might not be a disadvantage for SWL treatment in children with renal stone

Authors: Oktay Akça, Rahim Horuz, Mustafa Yücel Boz, Alper Kafkasli, Okan Gökhan, Cemal Göktaş, Kemal Sarica

Published in: International Urology and Nephrology | Issue 1/2013

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Abstract

Aim

Although the management of urinary stones in obese patients is a challenge and the impact of the patient-related parameter has been well studied in adults: No study has evaluated the possible impact of obesity in terms of body mass index related SWL success in pediatric population. In this present study, we aimed to evaluate the safety and efficiency of SWL in obese children in a comparative manner with the cases in normal BMI value limits.

Patients and methods

A total of 66 children (45 boys and 21 girls, M/F:2.1) with renal calculi were treated with SWL. Depending on the BMI values, the children were divided into two groups as; Group 1 (n:50) children with normal BMI values (mean: 16.1) and Group 2 (n:16) obese children with higher BMI values (mean: 20.3). The success rates, complications, and need for auxiliary procedures after SWL were evaluated between two groups of patients in a comparative manner. While majority of the cases were treated under general anesthesia (n:61), a limited number of cases were treated under neurolept anesthesia with PiezoLith 3000 (Richard Wolf GmbH) lithotripter. Evaluation of efficiency was based on radiological examinations using abdominal radiography, ultrasonography, or CT scan when needed.

Results

Both the mean age and mean stone size values were similar in both groups. While the mean age was 62 months (24–148) in Group 1, this value was 68 months (24–137) in Group 2. Again mean stone size was 10.26 mm(5–25 mm) in Group 1 and 10.12 mm (6–20 mm) in Group 2. The mean number of SWL sessions and the number of SW’s applied were similar in both groups (2.06 vs. 2.0 and 1975 vs. 1835, respectively). Evaluation of success rates after 3-months again did not show any statistically significant difference with respect to stone-free rates in both groups (47/50–94 %, 16/16–100 %, respectively). However, 3 children in Group 1 did show residual fragments (≤3 mm) which were followed closely with regular visits without any problem. In another 3 cases, again fragments migrated to involved ureter after lithotripsy and these fragments were successfully treated in situ with further SWL. With respect to auxiliary procedures, there was no specific procedure has been done in Group 2, but 3 cases did undergo further SWL for ureteral stones in Group 1. Stone location did not affect the final outcome of the procedure in a significant manner in both groups. Lastly, no serious complication could be demonstrated in both groups either during or after SWL procedures.

Conclusions

In the light of the successful treatment outcomes with limited need for auxiliary procedures in both groups, we may say that obesity might not be a disadvantage for SWL in children with renal stones.
Literature
1.
go back to reference Taylor EN, Stampfer MJ, Curhan GC (2005) Obesity, weight gain, and the risk of kidney stones. JAMA 293:455PubMedCrossRef Taylor EN, Stampfer MJ, Curhan GC (2005) Obesity, weight gain, and the risk of kidney stones. JAMA 293:455PubMedCrossRef
2.
go back to reference Semins MJ, Shore AD, Makary MA et al (2010) The association of increasing body mass index and kidney stone disease. J Urol 183:571PubMedCrossRef Semins MJ, Shore AD, Makary MA et al (2010) The association of increasing body mass index and kidney stone disease. J Urol 183:571PubMedCrossRef
4.
go back to reference Stamatelou KK, Francis ME, Jones CA et al (2003) Time trends in reported prevalence of kidney stones in the United States: 1976–1994. Kidney Intl 63:1817CrossRef Stamatelou KK, Francis ME, Jones CA et al (2003) Time trends in reported prevalence of kidney stones in the United States: 1976–1994. Kidney Intl 63:1817CrossRef
5.
go back to reference Siener R, Glatz S, Nicolay C et al (2004) The role of overweight and obesity in calcium oxalate Stone formation. Obesity Res 12:106CrossRef Siener R, Glatz S, Nicolay C et al (2004) The role of overweight and obesity in calcium oxalate Stone formation. Obesity Res 12:106CrossRef
7.
go back to reference Bush NC, Xu L, Brown BJ et al (2010) Hospitalizations for pediatric stone disease in United States, 2002–2007. J Urol 183:1151PubMedCrossRef Bush NC, Xu L, Brown BJ et al (2010) Hospitalizations for pediatric stone disease in United States, 2002–2007. J Urol 183:1151PubMedCrossRef
8.
go back to reference Erbağcı A, Erbağcı BA, Yılmaz M et al (2003) Pediatric urolithiasis: evaluation of risk factors in 95 children. Scand J Urol Nephrol 37:129–133PubMedCrossRef Erbağcı A, Erbağcı BA, Yılmaz M et al (2003) Pediatric urolithiasis: evaluation of risk factors in 95 children. Scand J Urol Nephrol 37:129–133PubMedCrossRef
9.
go back to reference Sarica K, Eryildirim B, Yencilek F et al (2009) Role of overweight status on stone-forming risk factors in children: a prospective study. Urology 73(5):1003–1007PubMedCrossRef Sarica K, Eryildirim B, Yencilek F et al (2009) Role of overweight status on stone-forming risk factors in children: a prospective study. Urology 73(5):1003–1007PubMedCrossRef
10.
go back to reference Gnessin E, Chertin L, Chertin B (2012) Current management of pediatric urolithiasis. Pediatr Surg Int 28(7):659–665PubMedCrossRef Gnessin E, Chertin L, Chertin B (2012) Current management of pediatric urolithiasis. Pediatr Surg Int 28(7):659–665PubMedCrossRef
11.
go back to reference Muslumanoglu AY, Tefekli A, Sarilar O et al (2003) Extracorporeal shock wave lithotripsy as first line treatment alternative for urinary tract stones in children: a large scale retrospective analysis. J Urol 170:2405–2408PubMedCrossRef Muslumanoglu AY, Tefekli A, Sarilar O et al (2003) Extracorporeal shock wave lithotripsy as first line treatment alternative for urinary tract stones in children: a large scale retrospective analysis. J Urol 170:2405–2408PubMedCrossRef
12.
go back to reference Rodrigues Netto N, Longo JA, Ikonomidis JA et al (2002) Extracorporeal shock wave lithotripsy in children. J Urol 167:2164–2166PubMedCrossRef Rodrigues Netto N, Longo JA, Ikonomidis JA et al (2002) Extracorporeal shock wave lithotripsy in children. J Urol 167:2164–2166PubMedCrossRef
13.
go back to reference Cortes JA, Motamedinia P, Gupta M (2011) Update on technological and selection factors influencing shockwave lithotripsy of renal stones in adults and children. Curr Opin Urol 21(2):134–140 ReviewPubMedCrossRef Cortes JA, Motamedinia P, Gupta M (2011) Update on technological and selection factors influencing shockwave lithotripsy of renal stones in adults and children. Curr Opin Urol 21(2):134–140 ReviewPubMedCrossRef
14.
go back to reference Tarawneh E, Awad Z, Hani A et al (2010) Factors affecting urinary calculi treatment by extracorporeal shock wave lithotripsy. Saudi J Kidney Dis Trans 21(4):660–665 Tarawneh E, Awad Z, Hani A et al (2010) Factors affecting urinary calculi treatment by extracorporeal shock wave lithotripsy. Saudi J Kidney Dis Trans 21(4):660–665
15.
go back to reference Pareek G, Hedican SP, Lee FT et al (2005) Shock wave lithotripsy success determined by skin-to-stone distance on computed tomography. J Urol 66:941–944CrossRef Pareek G, Hedican SP, Lee FT et al (2005) Shock wave lithotripsy success determined by skin-to-stone distance on computed tomography. J Urol 66:941–944CrossRef
16.
go back to reference Mezentsev VA (2005) Extracorporeal shock wave lithotripsy in the treatment of renal pelvicalyceal stones in morbidly obese patients. Int Braz J Urol 31(2):105–110PubMedCrossRef Mezentsev VA (2005) Extracorporeal shock wave lithotripsy in the treatment of renal pelvicalyceal stones in morbidly obese patients. Int Braz J Urol 31(2):105–110PubMedCrossRef
17.
go back to reference Olivi B, Védrine N, Costilles T et al (2011) Extra corporeal shock wave lithotripsy in patients with body mass index over 35 Kg/m2. Prog Urol 21(4):254–259PubMedCrossRef Olivi B, Védrine N, Costilles T et al (2011) Extra corporeal shock wave lithotripsy in patients with body mass index over 35 Kg/m2. Prog Urol 21(4):254–259PubMedCrossRef
18.
go back to reference Pareek G, Armenakas NA, Panagopoulos G et al (2005) Extracorporeal shock wave lithotripsy success based on body mass index and Hounsfield units. Urology 65(1):33–36PubMedCrossRef Pareek G, Armenakas NA, Panagopoulos G et al (2005) Extracorporeal shock wave lithotripsy success based on body mass index and Hounsfield units. Urology 65(1):33–36PubMedCrossRef
19.
go back to reference Thomas R, Cass AS (1993) Extracorporeal shock wave lithotripsy in morbidly obese patients. J Urol 150(1):30–32PubMed Thomas R, Cass AS (1993) Extracorporeal shock wave lithotripsy in morbidly obese patients. J Urol 150(1):30–32PubMed
20.
go back to reference Copelovitch L (2012) Urolithiasis in children: medical approach. Pediatr Clin North Am 59(4):881–96. Epub 2012 Jun 15 Copelovitch L (2012) Urolithiasis in children: medical approach. Pediatr Clin North Am 59(4):881–96. Epub 2012 Jun 15
21.
go back to reference Gabrielsen JS, Laciak RJ, Frank EL et al (2012) Pediatric urinary stone composition in United states. J Urol 187(6):2182–2187PubMedCrossRef Gabrielsen JS, Laciak RJ, Frank EL et al (2012) Pediatric urinary stone composition in United states. J Urol 187(6):2182–2187PubMedCrossRef
22.
go back to reference Valentini RP, Lakshmanan Y (2011) Nephrolithiasis in children. Adv Chronic Kidney Dis 18(5):370–375PubMedCrossRef Valentini RP, Lakshmanan Y (2011) Nephrolithiasis in children. Adv Chronic Kidney Dis 18(5):370–375PubMedCrossRef
23.
go back to reference Ayoob R, Wang W, Schwaderer A (2011) Body fat composition and occurence of kidney stones in hypercalciuric children. Pediatr Nephrol 26(12):2173–2178PubMedCrossRef Ayoob R, Wang W, Schwaderer A (2011) Body fat composition and occurence of kidney stones in hypercalciuric children. Pediatr Nephrol 26(12):2173–2178PubMedCrossRef
24.
go back to reference Eisner BH, Eisenberg ML, Stoller ML (2009) Influence of body mass index on quantitative 24-hour urine chemistry studies in children with urolithiasis. J Urol 182(3):1142–1145PubMedCrossRef Eisner BH, Eisenberg ML, Stoller ML (2009) Influence of body mass index on quantitative 24-hour urine chemistry studies in children with urolithiasis. J Urol 182(3):1142–1145PubMedCrossRef
25.
go back to reference Lahme S (2006) Shockwave lithotripsy and endourological stone treatment in children. Urol Res 34:112–117PubMedCrossRef Lahme S (2006) Shockwave lithotripsy and endourological stone treatment in children. Urol Res 34:112–117PubMedCrossRef
26.
go back to reference Sarica K (2008) Medical aspect and minimal invasive management of urinary stones in children. Arch Ital Urol Androl 80(2):43–49PubMed Sarica K (2008) Medical aspect and minimal invasive management of urinary stones in children. Arch Ital Urol Androl 80(2):43–49PubMed
27.
go back to reference Newman DM, Coury T, Lingeman JE et al (1986) Extracorporeal shock wave lithotripsy experience in children. J Urol 136:238–240PubMed Newman DM, Coury T, Lingeman JE et al (1986) Extracorporeal shock wave lithotripsy experience in children. J Urol 136:238–240PubMed
28.
go back to reference D’Addessi A, Bongiovanni L, Sasso F et al (2008) Reviews in Endourology: extracorporeal shockwave lithotripsy in pediatrics. J Endourol 22:1–11PubMedCrossRef D’Addessi A, Bongiovanni L, Sasso F et al (2008) Reviews in Endourology: extracorporeal shockwave lithotripsy in pediatrics. J Endourol 22:1–11PubMedCrossRef
29.
go back to reference Shukla AR, Hoover DL, Homsy YL et al (2001) Urolithiasis in the low birth weight infant: the role and efficacy of extracorporeal shock wave lithotripsy. J Urol 165:2320–2323PubMedCrossRef Shukla AR, Hoover DL, Homsy YL et al (2001) Urolithiasis in the low birth weight infant: the role and efficacy of extracorporeal shock wave lithotripsy. J Urol 165:2320–2323PubMedCrossRef
30.
go back to reference Ackermann DK, Fuhrimann R, Pfluger D et al (1994) Prognosis after extracorporeal shock wave lithotripsy of radiopaque renal calculi: a multivariate analysis. Eur Urol 25:105–109PubMed Ackermann DK, Fuhrimann R, Pfluger D et al (1994) Prognosis after extracorporeal shock wave lithotripsy of radiopaque renal calculi: a multivariate analysis. Eur Urol 25:105–109PubMed
Metadata
Title
Obesity might not be a disadvantage for SWL treatment in children with renal stone
Authors
Oktay Akça
Rahim Horuz
Mustafa Yücel Boz
Alper Kafkasli
Okan Gökhan
Cemal Göktaş
Kemal Sarica
Publication date
01-02-2013
Publisher
Springer Netherlands
Published in
International Urology and Nephrology / Issue 1/2013
Print ISSN: 0301-1623
Electronic ISSN: 1573-2584
DOI
https://doi.org/10.1007/s11255-012-0368-9

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