Skip to main content
Top
Published in: BMC Public Health 1/2010

Open Access 01-12-2010 | Research article

Obesity and mortality among older Thais: a four year follow up study

Authors: Patama Vapattanawong, Wichai Aekplakorn, Uthaithip Rakchanyaban, Pramote Prasartkul, Yawarat Porapakkham

Published in: BMC Public Health | Issue 1/2010

Login to get access

Abstract

Background

To assess the association of body mass index with mortality in a population-based setting of older people in Thailand.

Methods

Baseline data from the National Health Examination Survey III (NHES III) conducted in 2004 was linked to death records from vital registration for 2004-2007. Complete information regarding body mass index (BMI) (n = 15997) and mortality data were separately analysed by sex. The Cox Proportional Hazard Model was used to test the association between BMI and all-cause mortality controlling for demographic, socioeconomic, and health risk factors.

Results

During a mean follow-up time of 3.8 years (60545.8 person-years), a total of 1575 older persons, (936 men and 639 women) had died. A U-shaped and reverse J-shaped of association between BMI and all-cause mortality were observed in men and women, respectively. However there was no significant increased risk in the higher BMI categories. Compared to those with BMI 18.5-22.9 kg/m2, the adjusted hazard ratios (HR) of all-cause mortality for those with BMI <18.5, 23.0-24.9, 25.0-27.4, 27.5-29.9, 30.0-34.9, and ≥35.0 were 1.34 (95% CI, 1.14-1.58), 0.79 (95% CI, 0.65-0.97), 0.81 (95% CI, 0.65-1.00), 0.67 (95% CI, 0.48-0.94), 0.60 (95% CI, 0.35-1.03), and 1.87 (95% CI, 0.77-4.56), respectively, for men, and were 1.29 (95% CI,1.04-1.60), 0.70 (95% CI, 0.55-0.90), 0.79 (95% CI, 0.62-1.01), 0.57 (95% CI, 0.41-0.81), 0.58 (95% CI, 0.39-0.87), and 0.78 (95% CI, 0.38-1.59), respectively, for women.

Conclusions

The results of this study support the obesity paradox phenomenon in older Thai people, especially in women. Improvement in quality of mortality data and further investigation to confirm such association are needed in this population.
Appendix
Available only for authorised users
Literature
2.
3.
go back to reference Ezzati M, Lopez AD, Rodgers A, Vander Hoorn S, Murray CJ, Comparative Risk Assessment Collaborating Group: Selected major risk factors and global and regional burden of disease. Lancet. 2002, 360: 1347-1360. 10.1016/S0140-6736(02)11403-6.CrossRefPubMed Ezzati M, Lopez AD, Rodgers A, Vander Hoorn S, Murray CJ, Comparative Risk Assessment Collaborating Group: Selected major risk factors and global and regional burden of disease. Lancet. 2002, 360: 1347-1360. 10.1016/S0140-6736(02)11403-6.CrossRefPubMed
4.
go back to reference Manosoontorn S: Attributable fraction of obesity in Thailand. J Health Sci. 2005, 14: 337-344. Manosoontorn S: Attributable fraction of obesity in Thailand. J Health Sci. 2005, 14: 337-344.
5.
go back to reference Ministry of Public Health: Public Health Statistics AD 2006. 2006, Nonthaburi, Bureau of Health Policy and Strategy Ministry of Public Health: Public Health Statistics AD 2006. 2006, Nonthaburi, Bureau of Health Policy and Strategy
6.
go back to reference Aekplakorn W, Chaiyapong Y, Neal B, Chariyalertsak S, Kunanusont C, Phoolcharoen W, Suriyawongpaisal P: Prevalence and determinants of overweight and obesity in Thai adults: results of the second National Health Examination Survey. J Med Assoc Thai. 2004, 87: 685-693.PubMed Aekplakorn W, Chaiyapong Y, Neal B, Chariyalertsak S, Kunanusont C, Phoolcharoen W, Suriyawongpaisal P: Prevalence and determinants of overweight and obesity in Thai adults: results of the second National Health Examination Survey. J Med Assoc Thai. 2004, 87: 685-693.PubMed
7.
go back to reference Kantachuvessiri A: Obesity in Thailand. J Med Assoc Thai. 2005, 88: 554-562.PubMed Kantachuvessiri A: Obesity in Thailand. J Med Assoc Thai. 2005, 88: 554-562.PubMed
8.
go back to reference Aekplakorn W, Hogan MC, Chongsuvivivatwong V, Tatsanavivat P, Chariyalertsak S, Boonthum A, Tiptaradol S, Lim SS: Trends in obesity and associations with education and urban or rural residence in Thailand. Obesity. 2007, 15: 3113-3121. 10.1038/oby.2007.371.CrossRefPubMed Aekplakorn W, Hogan MC, Chongsuvivivatwong V, Tatsanavivat P, Chariyalertsak S, Boonthum A, Tiptaradol S, Lim SS: Trends in obesity and associations with education and urban or rural residence in Thailand. Obesity. 2007, 15: 3113-3121. 10.1038/oby.2007.371.CrossRefPubMed
9.
go back to reference Aekplakorn W, Abbott-Klafter J, Premgamone A, Dhanamun B, Chaikittiporn C, Chongsuvivatwong V, Suwanprapisa T, Chaipornsupaisan W, Tiptaradol S, Lim SS: Prevalence and management of diabetes and associated risk factors by regions of Thailand: third National Health Examination Survey 2004. Diabetes Care. 2007, 30: 2007-2012. 10.2337/dc06-2319.CrossRefPubMed Aekplakorn W, Abbott-Klafter J, Premgamone A, Dhanamun B, Chaikittiporn C, Chongsuvivatwong V, Suwanprapisa T, Chaipornsupaisan W, Tiptaradol S, Lim SS: Prevalence and management of diabetes and associated risk factors by regions of Thailand: third National Health Examination Survey 2004. Diabetes Care. 2007, 30: 2007-2012. 10.2337/dc06-2319.CrossRefPubMed
10.
go back to reference Aekplakorn W, Abbott-Klafter J, Khonputsa P, Tatsanavivat P, Chongsuvivatwong V, Chariyalertsak S, Sangwatanaroj S, Tiptaradol S, Lim SS: Prevalence and management of prehypertension and hypertension by geographic regions of Thailand: the third National Health Examination Survey, 2004. J Hypertens. 2008, 26: 191-198. 10.1097/HJH.0b013e3282f09f57.CrossRefPubMed Aekplakorn W, Abbott-Klafter J, Khonputsa P, Tatsanavivat P, Chongsuvivatwong V, Chariyalertsak S, Sangwatanaroj S, Tiptaradol S, Lim SS: Prevalence and management of prehypertension and hypertension by geographic regions of Thailand: the third National Health Examination Survey, 2004. J Hypertens. 2008, 26: 191-198. 10.1097/HJH.0b013e3282f09f57.CrossRefPubMed
11.
go back to reference Porapakkham Y, Pattaraarchachai J, Aekplakorn W: Prevalence, awareness, treatment and control of hypertension and diabetes mellitus among the elderly: the 2004 National Health Examination Survey III, Thailand. Singapore Med J. 2008, 49: 868-873.PubMed Porapakkham Y, Pattaraarchachai J, Aekplakorn W: Prevalence, awareness, treatment and control of hypertension and diabetes mellitus among the elderly: the 2004 National Health Examination Survey III, Thailand. Singapore Med J. 2008, 49: 868-873.PubMed
12.
go back to reference Aekplakorn W, Mo-suwan L: Prevalence of obesity in Thailand. Obes Rev. 2009, 10: 589-592. 10.1111/j.1467-789X.2009.00626.x.CrossRefPubMed Aekplakorn W, Mo-suwan L: Prevalence of obesity in Thailand. Obes Rev. 2009, 10: 589-592. 10.1111/j.1467-789X.2009.00626.x.CrossRefPubMed
13.
go back to reference Master AM, Lasser RP, Beckman G: Tables of average weight and height of Americans aged 65 to 94 years, relationship of weight and height to survival. JAMA. 1960, 172: 656-662. Master AM, Lasser RP, Beckman G: Tables of average weight and height of Americans aged 65 to 94 years, relationship of weight and height to survival. JAMA. 1960, 172: 656-662.
14.
go back to reference Lew EA, Garfinkel L: Variations in mortality by weight among 750,000 men and women. J Chronic Dis. 1979, 32: 563-576. 10.1016/0021-9681(79)90119-X.CrossRefPubMed Lew EA, Garfinkel L: Variations in mortality by weight among 750,000 men and women. J Chronic Dis. 1979, 32: 563-576. 10.1016/0021-9681(79)90119-X.CrossRefPubMed
15.
go back to reference Waaler HT: Height, weight and mortality: the Norwegian experience. Acta Med Scand Suppl. 1984, 679: 1-56.PubMed Waaler HT: Height, weight and mortality: the Norwegian experience. Acta Med Scand Suppl. 1984, 679: 1-56.PubMed
16.
go back to reference Manson JE, Stampfer MJ, Hennekens CH, Willett WC: Body weight and longevity: a reassessment. JAMA. 1987, 257: 353-358. 10.1001/jama.257.3.353.CrossRefPubMed Manson JE, Stampfer MJ, Hennekens CH, Willett WC: Body weight and longevity: a reassessment. JAMA. 1987, 257: 353-358. 10.1001/jama.257.3.353.CrossRefPubMed
17.
go back to reference Kinney EL, Caldwell JW: Relationship between body weight and mortality in men aged 75 years and older. Southern Med J. 1990, 83: 1256-1258.CrossRefPubMed Kinney EL, Caldwell JW: Relationship between body weight and mortality in men aged 75 years and older. Southern Med J. 1990, 83: 1256-1258.CrossRefPubMed
18.
go back to reference Manson JE, Willett WC, Stampfer MJ, Colditz GA, Hunter DJ, Hankinson SE, Hennekens CH, Speizer FE: Body weight and mortality among women. New Eng J Med. 1995, 333: 677-685. 10.1056/NEJM199509143331101.CrossRefPubMed Manson JE, Willett WC, Stampfer MJ, Colditz GA, Hunter DJ, Hankinson SE, Hennekens CH, Speizer FE: Body weight and mortality among women. New Eng J Med. 1995, 333: 677-685. 10.1056/NEJM199509143331101.CrossRefPubMed
19.
go back to reference Solomon CG, Manson JE: Obesity and mortality: a review of the epidemiologic data. Am J Clin Nutr. 1997, 66 (suppl): 1044S-1050S.PubMed Solomon CG, Manson JE: Obesity and mortality: a review of the epidemiologic data. Am J Clin Nutr. 1997, 66 (suppl): 1044S-1050S.PubMed
20.
go back to reference Calle EE, Thun MJ, Petrelli JM, Rodriguez C, Heath CW: Body-mass index and mortallity in a prospective cohort of U.S. adults. New Eng J Med. 1999, 341: 1097-1105. 10.1056/NEJM199910073411501.CrossRefPubMed Calle EE, Thun MJ, Petrelli JM, Rodriguez C, Heath CW: Body-mass index and mortallity in a prospective cohort of U.S. adults. New Eng J Med. 1999, 341: 1097-1105. 10.1056/NEJM199910073411501.CrossRefPubMed
21.
go back to reference Adams KF, Schatzkin A, Harris TB, Kipnis V, Mouw T, Ballard-Barbash R, Hollenbeck A, Leitzmann MF: Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old. New Eng J Med. 2006, 355: 763-777. 10.1056/NEJMoa055643.CrossRefPubMed Adams KF, Schatzkin A, Harris TB, Kipnis V, Mouw T, Ballard-Barbash R, Hollenbeck A, Leitzmann MF: Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old. New Eng J Med. 2006, 355: 763-777. 10.1056/NEJMoa055643.CrossRefPubMed
22.
go back to reference Orpana HM, Berthelot JM, Kaplan MS, Feeny DH, McFarland B, Ross NA: BMI and mortality: results from a national longitudinal study of Canadian adults. Obesity. 2009, 18: 214-218. 10.1038/oby.2009.191.CrossRefPubMed Orpana HM, Berthelot JM, Kaplan MS, Feeny DH, McFarland B, Ross NA: BMI and mortality: results from a national longitudinal study of Canadian adults. Obesity. 2009, 18: 214-218. 10.1038/oby.2009.191.CrossRefPubMed
23.
go back to reference Gu D, He J, Duan X, et al: Body weight and mortality among men and women in China. JAMA. 2006, 295: 776-783. 10.1001/jama.295.7.776.CrossRefPubMed Gu D, He J, Duan X, et al: Body weight and mortality among men and women in China. JAMA. 2006, 295: 776-783. 10.1001/jama.295.7.776.CrossRefPubMed
25.
go back to reference World Health Organization: WHO Expert Committee on Physical Status: The Use and Interpretation of Anthropometry. 1995, Geneva: World Health Organization, (Tech. Rep. Ser., no. 854) World Health Organization: WHO Expert Committee on Physical Status: The Use and Interpretation of Anthropometry. 1995, Geneva: World Health Organization, (Tech. Rep. Ser., no. 854)
26.
go back to reference National Statistical Office: Report on the 1995 - 1996 Survey of Population Change. 1997, Bangkok: Statistical Data Bank and Information Dissemination Division National Statistical Office: Report on the 1995 - 1996 Survey of Population Change. 1997, Bangkok: Statistical Data Bank and Information Dissemination Division
27.
go back to reference National Statistical Office: Report on the 2005 - 2006 Survey of Population Change. 2007, Bangkok: Statistical Forecasting Bureau National Statistical Office: Report on the 2005 - 2006 Survey of Population Change. 2007, Bangkok: Statistical Forecasting Bureau
28.
go back to reference WHO expert consultation: Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet. 2004, 363: 157-163. 10.1016/S0140-6736(03)15268-3.CrossRef WHO expert consultation: Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet. 2004, 363: 157-163. 10.1016/S0140-6736(03)15268-3.CrossRef
29.
go back to reference ADA: Diagnosis and classification of diabetes mellitus. Diabetes Care. 2008, 31 (suppl 1): s55-s60. ADA: Diagnosis and classification of diabetes mellitus. Diabetes Care. 2008, 31 (suppl 1): s55-s60.
30.
go back to reference Asia Pacific Cohort Studies Collaboration: Blood pressure and cardiovascular diseases in the Asia-Pacific region. J Hypertens. 2003, 21: 707-716. 10.1097/00004872-200304000-00013.CrossRef Asia Pacific Cohort Studies Collaboration: Blood pressure and cardiovascular diseases in the Asia-Pacific region. J Hypertens. 2003, 21: 707-716. 10.1097/00004872-200304000-00013.CrossRef
31.
go back to reference Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults: Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA. 2001, 285: 2486-2497. 10.1001/jama.285.19.2486.CrossRef Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults: Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA. 2001, 285: 2486-2497. 10.1001/jama.285.19.2486.CrossRef
32.
go back to reference WHO: WHO STEPS Instrument (Core and Expanded): The WHO STEPwise Approach to Chronic Disease Risk Factor Surveillance (STEPS). 2002, Geneva: World Health Organization WHO: WHO STEPS Instrument (Core and Expanded): The WHO STEPwise Approach to Chronic Disease Risk Factor Surveillance (STEPS). 2002, Geneva: World Health Organization
33.
go back to reference Breeze E, Clarke R, Shipley MJ, Marmot MG, Fletcher AE: Cause-specific mortality in old age in relation to body mass index in middle age and in old age: follow-up of the Whitehall cohort of male civil servants. Int J Epidimiol. 2006, 35: 169-178. 10.1093/ije/dyi212.CrossRef Breeze E, Clarke R, Shipley MJ, Marmot MG, Fletcher AE: Cause-specific mortality in old age in relation to body mass index in middle age and in old age: follow-up of the Whitehall cohort of male civil servants. Int J Epidimiol. 2006, 35: 169-178. 10.1093/ije/dyi212.CrossRef
34.
go back to reference Flegal KM, Graubard BI, Williamson DF, Gail MH: Excess deaths associated with underweight, overweight, and obesity. JAMA. 2005, 293: 1861-1867. 10.1001/jama.293.15.1861.CrossRefPubMed Flegal KM, Graubard BI, Williamson DF, Gail MH: Excess deaths associated with underweight, overweight, and obesity. JAMA. 2005, 293: 1861-1867. 10.1001/jama.293.15.1861.CrossRefPubMed
35.
go back to reference Katzmarzyk PT, Craig CL, Bouchard C: Underweight, overweight and obesity: relationships with mortality in the 13-year follow-up of the Canada Fitness Survey. J Clin Epidemiol. 2001, 54: 916-920. 10.1016/S0895-4356(01)00356-0.CrossRefPubMed Katzmarzyk PT, Craig CL, Bouchard C: Underweight, overweight and obesity: relationships with mortality in the 13-year follow-up of the Canada Fitness Survey. J Clin Epidemiol. 2001, 54: 916-920. 10.1016/S0895-4356(01)00356-0.CrossRefPubMed
36.
go back to reference Taylor DH, Østbye T: The effect of middle- and old-age body mass index on short-term mortality in older people. JAGS. 2001, 49: 1319-1326. 10.1046/j.1532-5415.2001.49259.x.CrossRef Taylor DH, Østbye T: The effect of middle- and old-age body mass index on short-term mortality in older people. JAGS. 2001, 49: 1319-1326. 10.1046/j.1532-5415.2001.49259.x.CrossRef
37.
go back to reference Oreopoulos A, Kalantar-Zadeh K, Sharma AM, Fonarow GC: The obesity paradox in the elderly: potential mechanisms and clinical implications. Clin Geriatr Med. 2009, 25: 643-659. 10.1016/j.cger.2009.07.005.CrossRefPubMed Oreopoulos A, Kalantar-Zadeh K, Sharma AM, Fonarow GC: The obesity paradox in the elderly: potential mechanisms and clinical implications. Clin Geriatr Med. 2009, 25: 643-659. 10.1016/j.cger.2009.07.005.CrossRefPubMed
38.
go back to reference Lavie CJ, Milani RV, Ventura HO: Obesity and cardiovascular disease: risk factor, paradox, and impact of weight loss. J Am Coll Cardiol. 2009, 53: 1925-1932. 10.1016/j.jacc.2008.12.068.CrossRefPubMed Lavie CJ, Milani RV, Ventura HO: Obesity and cardiovascular disease: risk factor, paradox, and impact of weight loss. J Am Coll Cardiol. 2009, 53: 1925-1932. 10.1016/j.jacc.2008.12.068.CrossRefPubMed
39.
go back to reference Editorial: The obesity paradox: perception vs knowledge. Mayo Clin Proc. 2010, 85: 112-114. 10.4065/mcp.2009.0777. Editorial: The obesity paradox: perception vs knowledge. Mayo Clin Proc. 2010, 85: 112-114. 10.4065/mcp.2009.0777.
40.
go back to reference Lavie CJ, Milani RV, Artham SM, Patel DA: The obesity paradox, weight loss, and coronary disease. Am J Med. 2009, 122: 1106-1114. 10.1016/j.amjmed.2009.06.006.CrossRefPubMed Lavie CJ, Milani RV, Artham SM, Patel DA: The obesity paradox, weight loss, and coronary disease. Am J Med. 2009, 122: 1106-1114. 10.1016/j.amjmed.2009.06.006.CrossRefPubMed
41.
go back to reference Artham SM, Lavie CJ, Patel DA, Ventura HO: Obesity paradox in the elderly: is fatter really fatter?. Ageing Health. 2009, 5: 177-184. 10.2217/ahe.09.12.CrossRef Artham SM, Lavie CJ, Patel DA, Ventura HO: Obesity paradox in the elderly: is fatter really fatter?. Ageing Health. 2009, 5: 177-184. 10.2217/ahe.09.12.CrossRef
Metadata
Title
Obesity and mortality among older Thais: a four year follow up study
Authors
Patama Vapattanawong
Wichai Aekplakorn
Uthaithip Rakchanyaban
Pramote Prasartkul
Yawarat Porapakkham
Publication date
01-12-2010
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2010
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/1471-2458-10-604

Other articles of this Issue 1/2010

BMC Public Health 1/2010 Go to the issue