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European Journal of Epidemiology
Published in: European Journal of Epidemiology 3/2015

01-03-2015 | META-ANALYSIS

Nut consumption and risk of stroke

Authors: Zhizhong Zhang, Gelin Xu, Yongyue Wei, Wusheng Zhu, Xinfeng Liu

Published in: European Journal of Epidemiology | Issue 3/2015

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Abstract

Nut consumption has been inconsistently associated with risk of stroke. Our aim was to carry out a meta-analysis of prospective studies to assess the relation between nut consumption and stroke risk and mortality. Pertinent studies were identified by a search of PubMed and Embase through June 2014 and by reviewing the references of retrieved articles. Prospective cohort studies that reported relative risks (RRs) with 95 % confidence intervals (CIs) for the association between nut consumption and risk of stroke were included. Six articles including nine independent prospective cohorts with 476,181 participants were included in the meta-analysis. The pooled RR of stroke was 0.90 (95 % CI 0.83–0.98) comparing the highest with the lowest nut consumption. Stratifying by gender, significant inverse association was observed for females (RR 0.88; 95 % CI 0.78–0.98). Sensitivity analysis restricted to studies with adjustment for common confounding factors showed similar results, strengthening the association between nut consumption and stroke risk. Moreover, we observed a trend toward an inverse association between higher nut consumption and stroke mortality (RR 0.86; 95 % CI 0.69–1.06), although it is not significant. Current evidence indicated that nut consumption is inversely associated with risk of stroke.
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Metadata
Title
Nut consumption and risk of stroke
Authors
Zhizhong Zhang
Gelin Xu
Yongyue Wei
Wusheng Zhu
Xinfeng Liu
Publication date
01-03-2015
Publisher
Springer Netherlands
Published in
European Journal of Epidemiology / Issue 3/2015
Print ISSN: 0393-2990
Electronic ISSN: 1573-7284
DOI
https://doi.org/10.1007/s10654-015-9999-3

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