Published in:
01-03-2014 | Cardiac Nuclear Imaging (A Cuocolo Section Editor)
Nuclear Cardiology in Heart Failure
Authors:
Selene Capitanio, Cecilia Marini, Matteo Bauckneht, Gianmario Sambuceti
Published in:
Current Cardiovascular Imaging Reports
|
Issue 3/2014
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Abstract
Despite recent advances in drug and non-pharmacological treatments, heart failure represents a serious public health problem that is steadily increasing in developed countries. A deeper comprehension of mechanisms underlying this condition still remains the only way to decrease morbidity and mortality in these patients. To this purpose, integrated information on heart failure etiology and pathophysiology is needed for an accurate prediction of patient outcome. Among the currently available non-invasive imaging techniques, nuclear medicine has a peculiar role due to its capability to simultaneously evaluate different aspects of disease and to provide insights into the molecular and cellular mechanisms involved in progression of left ventricular dysfunction. This review aims to synthetically describe possibilities and problems in the radionuclide evaluation of myocardial function, perfusion, innervation and molecular pathways underlying heart failure progression and its complications.