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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 3/2020

01-12-2020 | NSCLC | ASO Author Reflections

ASO Author Reflections: Individualized Mediastinal Lymph Node Dissection for Lung Cancer: Do Not Neglect Station 3A Lymph Node

Authors: Chengwu Liu, MD, Shiyou Wei, MD, Lunxu Liu, MD, PhD, FRCS

Published in: Annals of Surgical Oncology | Special Issue 3/2020

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Excerpt

Mediastinal lymph node (LN) dissection is an important component in lung cancer surgery due to its crucial impact on accurate lymph node staging and potential therapeutic effect on micrometastasis.1 Station 3A LN is located in the anterior mediastinum and in front of superior vena cava. In the past, station 3A LN was considered as a side path of lymphatic spread because of the hindrance of superior vena cava. Therefore, tumor metastasis to this position might be uncommon.2 As a result, station 3A LN dissection in patients with right-sided non-small cell lung cancer (NSCLC) is generally neglected during routine clinical practice. Previous sporadic studies have reported the removal of station 3A LNs with the metastasis rate ranging from 2.9 to 17.8%,2,3 indicating that the involvement of station 3A LNs was not rare. However, the clinical significance of station 3A LN dissection in patients with right-sided NSCLC is mostly unknown. …
Literature
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Asamura H, Chansky K, Crowley J, et al. The International Association for the Study of Lung Cancer Lung Cancer staging project: proposals for the revision of the N descriptors in the forthcoming 8th edition of the TNM classification for lung cancer. J Thorac Oncol. 2015; 10(12):1675–84.CrossRef
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Zheng H, Gao W, Fei K, et al. Prognostic role of station 3A mediastinal nodes for non-small-cell lung cancers. Interact Cardiovasc Thorac Surg. 2013;17(3):447–54.CrossRef
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Naruke T, Tsuchiya R, Kondo H, et al. Lymph node sampling in lung cancer: how should it be done? Eur J Cardiothorac Surg. 1999;16 Suppl 1:S17–24.CrossRef
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Zhao K, Wei S, Mei J, et al. Survival benefit of left lower paratracheal (4L) lymph node dissection for patients with left-sided non-small cell lung cancer: once neglected but of great importance. Ann Surg Oncol. 2019;26(7):2044–52.CrossRef
Metadata
Title
ASO Author Reflections: Individualized Mediastinal Lymph Node Dissection for Lung Cancer: Do Not Neglect Station 3A Lymph Node
Authors
Chengwu Liu, MD
Shiyou Wei, MD
Lunxu Liu, MD, PhD, FRCS
Publication date
01-12-2020
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue Special Issue 3/2020
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-020-08876-x

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