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Journal of Cardiothoracic Surgery
Published in: Journal of Cardiothoracic Surgery 1/2022

Open Access 01-12-2022 | NSCLC | Research

The perioperative outcomes of uniport versus two-port and three-port video-assisted thoracoscopic surgery in lung cancer: a systematic review and meta-analysis

Authors: Ya-Fu Cheng, Chang-Lun Huang, Wei-Heng Hung, Ching-Yuan Cheng, Bing-Yen Wang

Published in: Journal of Cardiothoracic Surgery | Issue 1/2022

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Abstract

Background

Uniport video-assisted thoracoscopic surgery (VATS) has been applied widely for the treatment of lung cancer in recent years. Some studies have reported that uniport VATS might provide better outcomes than multiport VATS. However, the perioperative outcomes of uniport VATS compared with two-port and three-port VATS, respectively, have yet to be studied at a comprehensive scale. This meta-analysis study compares the perioperative efficacy among uniport, two-port, and three-port VATS.

Methods

We searched studies published before October 1, 2019, by using Web of Science databases, Ovid Medline, Embase, and PubMed. Studies that compared uniport VATS with two-port or three-port VATS for patients with lung cancer were included. Operative time, perioperative blood loss, number of lymph nodes retrieved, conversion rate, duration of postoperative chest tube drainage, length of hospital stay (LoS), visual analogue pain scores on postoperative day (POD) 1 and POD 3, and overall morbidity were evaluated.

Results

Sixteen studies that compared uniport VATS with two-port or three-port VATS in the treatment of lung cancer were included. Uniport VATS showed less blood loss, a shorter duration of postoperative drainage and a lower visual analogue pain score on POD 3 than two-port VATS; it showed a shorter duration of postoperative drainage, a shorter LoS, and lower visual analogue pain scores on POD 1 and POD 3 than three-port VATS. There were no significant differences in the number of lymph nodes retrieved, operative time, conversion rate, and overall morbidity rate when comparing uniport VATS with two-port VATS or three-port VATS.

Conclusions

Uniport VATS might provide better perioperative outcomes than either two-port or three-port VATS in lung cancer treatment.
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Metadata
Title
The perioperative outcomes of uniport versus two-port and three-port video-assisted thoracoscopic surgery in lung cancer: a systematic review and meta-analysis
Authors
Ya-Fu Cheng
Chang-Lun Huang
Wei-Heng Hung
Ching-Yuan Cheng
Bing-Yen Wang
Publication date
01-12-2022
Publisher
BioMed Central
Published in
Journal of Cardiothoracic Surgery / Issue 1/2022
Electronic ISSN: 1749-8090
DOI
https://doi.org/10.1186/s13019-022-02034-y

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