Skip to main content
Top
Published in: European Journal of Epidemiology 3/2011

Open Access 01-03-2011 | Infectious Diseases

Nowcasting pandemic influenza A/H1N1 2009 hospitalizations in the Netherlands

Authors: Tjibbe Donker, Michiel van Boven, W. Marijn van Ballegooijen, Tessa M. van’t Klooster, Cornelia C. Wielders, Jacco Wallinga

Published in: European Journal of Epidemiology | Issue 3/2011

Login to get access

Abstract

During emerging epidemics of infectious diseases, it is vital to have up-to-date information on epidemic trends, such as incidence or health care demand, because hospitals and intensive care units have limited excess capacity. However, real-time tracking of epidemics is difficult, because of the inherent delay between onset of symptoms or hospitalizations, and reporting. We propose a robust algorithm to correct for reporting delays, using the observed distribution of reporting delays. We apply the algorithm to pandemic influenza A/H1N1 2009 hospitalizations as reported in the Netherlands. We show that the proposed algorithm is able to provide unbiased predictions of the actual number of hospitalizations in real-time during the ascent and descent of the epidemic. The real-time predictions of admissions are useful to adjust planning in hospitals to avoid exceeding their capacity.
Literature
1.
go back to reference Fraser C, Donnelly CA, Cauchemez S, Hanage WP, Van Kerkhove MD, Hollingsworth TD, et al. (2009) Pandemic potential of a strain of influenza A (H1N1): early findings. Science. 2009;324(5934):1557–61.PubMedCrossRef Fraser C, Donnelly CA, Cauchemez S, Hanage WP, Van Kerkhove MD, Hollingsworth TD, et al. (2009) Pandemic potential of a strain of influenza A (H1N1): early findings. Science. 2009;324(5934):1557–61.PubMedCrossRef
2.
go back to reference Presanis AM, De Angelis D, Hagy A, Reed C, Riley S, Cooper BS, et al. (2009) The severity of pandemic H1N1 influenza in the United States, from April to July 2009: a Bayesian analysis. PLoS Med. 2009;6(12):e1000207.PubMedCrossRef Presanis AM, De Angelis D, Hagy A, Reed C, Riley S, Cooper BS, et al. (2009) The severity of pandemic H1N1 influenza in the United States, from April to July 2009: a Bayesian analysis. PLoS Med. 2009;6(12):e1000207.PubMedCrossRef
3.
go back to reference Wu JT, Cowling BJ, Lau EHY, Ip DKM, Ho LM, Tsang T, et al. (2010) School closure and mitigation of pandemic (H1N1) 2009, Hong Kong. Emer Infect Dis. 2010;16(3):538–41. Wu JT, Cowling BJ, Lau EHY, Ip DKM, Ho LM, Tsang T, et al. (2010) School closure and mitigation of pandemic (H1N1) 2009, Hong Kong. Emer Infect Dis. 2010;16(3):538–41.
4.
go back to reference Domínguez-Cherit G, Lapinsky SE, Macias AE, Pinto R, Espinosa-Perez L, de la Torre A, et al. Critically Ill patients with 2009 influenza A(H1N1) in Mexico. JAMA. 2009;302(17):1880–7.PubMedCrossRef Domínguez-Cherit G, Lapinsky SE, Macias AE, Pinto R, Espinosa-Perez L, de la Torre A, et al. Critically Ill patients with 2009 influenza A(H1N1) in Mexico. JAMA. 2009;302(17):1880–7.PubMedCrossRef
5.
go back to reference Kumar A, Zarychanski R, Pinto R, Cook DJ, Marshall J, Lacroix J, et al. (2009) Critically ill patients with 2009 influenza A(H1N1) infection in Canada. JAMA. 2009;302(17):1872–9.PubMedCrossRef Kumar A, Zarychanski R, Pinto R, Cook DJ, Marshall J, Lacroix J, et al. (2009) Critically ill patients with 2009 influenza A(H1N1) infection in Canada. JAMA. 2009;302(17):1872–9.PubMedCrossRef
6.
go back to reference Carr BG, Addyson DK, Kahn JM. Variation in critical care beds per capita in the United States: implications for pandemic and disaster planning. JAMA. 2010;303(14):1371–2.CrossRef Carr BG, Addyson DK, Kahn JM. Variation in critical care beds per capita in the United States: implications for pandemic and disaster planning. JAMA. 2010;303(14):1371–2.CrossRef
7.
go back to reference Hansen J, Van Der Velden LFJ, Hingstman L. Intensive care needs assessment for adults 2006–2016 (Behoefteraming Intensive Care voor Volwassenen 2006–2016). 2008. Hansen J, Van Der Velden LFJ, Hingstman L. Intensive care needs assessment for adults 2006–2016 (Behoefteraming Intensive Care voor Volwassenen 2006–2016). 2008.
8.
go back to reference White DB, Angus DC. Preparing for the sickest patients with 2009 influenza A(H1N1). JAMA. 2009;302(17):1905–6.PubMedCrossRef White DB, Angus DC. Preparing for the sickest patients with 2009 influenza A(H1N1). JAMA. 2009;302(17):1905–6.PubMedCrossRef
9.
go back to reference Farrington CP, Andrews NJ, Beale AD, Catchpole MA. A statistical algorithm for the early detection of outbreaks of infectious disease. J R Stat Soci Ser A (Stat Soci). 1996;159(3):547–63.CrossRef Farrington CP, Andrews NJ, Beale AD, Catchpole MA. A statistical algorithm for the early detection of outbreaks of infectious disease. J R Stat Soci Ser A (Stat Soci). 1996;159(3):547–63.CrossRef
10.
go back to reference Garske T, Legrand J, Donnelly CA, Ward H, Cauchemez S, Fraser C, et al. Assessing the severity of the novel influenza A/H1N1 pandemic. BMJ. 2009;339:b2840.PubMedCrossRef Garske T, Legrand J, Donnelly CA, Ward H, Cauchemez S, Fraser C, et al. Assessing the severity of the novel influenza A/H1N1 pandemic. BMJ. 2009;339:b2840.PubMedCrossRef
11.
go back to reference Nicoll A, Ammon A, Amato Gauci A, Amato A, Ciancio B, Zucs P, et al. Experience and lessons from surveillance and studies of the 2009 pandemic in Europe. Public Health. 2010;124(1):14–23.PubMedCrossRef Nicoll A, Ammon A, Amato Gauci A, Amato A, Ciancio B, Zucs P, et al. Experience and lessons from surveillance and studies of the 2009 pandemic in Europe. Public Health. 2010;124(1):14–23.PubMedCrossRef
12.
go back to reference Hahné S, Donker T, Meijer A, Van Steenbergen J, Osterhaus A, Van Der Sande M, et al. Epidemiology and control of influenza A(H1N1)v in the Netherlands: the first 115 cases. Eurosurveillance. 2009;14(27):1–4. Hahné S, Donker T, Meijer A, Van Steenbergen J, Osterhaus A, Van Der Sande M, et al. Epidemiology and control of influenza A(H1N1)v in the Netherlands: the first 115 cases. Eurosurveillance. 2009;14(27):1–4.
13.
go back to reference Hubbard AE, Van der Laan MJ, Enanoria W, Colford JM. Nonparametric survival estimation when death is reported with delay. Lifetime Data Anal. 2000;6(3):237–50.PubMedCrossRef Hubbard AE, Van der Laan MJ, Enanoria W, Colford JM. Nonparametric survival estimation when death is reported with delay. Lifetime Data Anal. 2000;6(3):237–50.PubMedCrossRef
14.
go back to reference Hall IM, Gani R, Hughes HE, Leach S. Real-time epidemic forecasting for pandemic influenza. Epidemiol Infect. 2007;135(3):372–85.PubMedCrossRef Hall IM, Gani R, Hughes HE, Leach S. Real-time epidemic forecasting for pandemic influenza. Epidemiol Infect. 2007;135(3):372–85.PubMedCrossRef
15.
go back to reference Ong JB, Chen MI, Cook AR, Lee HC, Lee VJ, Lin RT, et al. Real-time epidemic monitoring and forecasting of H1N1-2009 using influenza-like illness from general practice and family doctor clinics in Singapore. PloS One. 2010;5(4):e10036.PubMedCrossRef Ong JB, Chen MI, Cook AR, Lee HC, Lee VJ, Lin RT, et al. Real-time epidemic monitoring and forecasting of H1N1-2009 using influenza-like illness from general practice and family doctor clinics in Singapore. PloS One. 2010;5(4):e10036.PubMedCrossRef
16.
go back to reference Nishiura H. Real-time forecasting of an epidemic using a discrete time stochastic model: a case study of pandemic influenza (H1N1-2009). Biomedical engineering online. 2011;10(1). Nishiura H. Real-time forecasting of an epidemic using a discrete time stochastic model: a case study of pandemic influenza (H1N1-2009). Biomedical engineering online. 2011;10(1).
Metadata
Title
Nowcasting pandemic influenza A/H1N1 2009 hospitalizations in the Netherlands
Authors
Tjibbe Donker
Michiel van Boven
W. Marijn van Ballegooijen
Tessa M. van’t Klooster
Cornelia C. Wielders
Jacco Wallinga
Publication date
01-03-2011
Publisher
Springer Netherlands
Published in
European Journal of Epidemiology / Issue 3/2011
Print ISSN: 0393-2990
Electronic ISSN: 1573-7284
DOI
https://doi.org/10.1007/s10654-011-9566-5

Other articles of this Issue 3/2011

European Journal of Epidemiology 3/2011 Go to the issue