Top

Published in:

Open Access 01-12-2011 | Short report

Novel snake papillomavirus does not cluster with other non-mammalian papillomaviruses

Authors: Christian E Lange, Claude Favrot, Mathias Ackermann, Jessica Gull, Elisabeth Vetsch, Kurt Tobler

Published in: Virology Journal | Issue 1/2011

Abstract

Papillomaviruses (PVs) are associated with the development of neoplasias and have been found in several different species, most of them in humans and other mammals. We identified, cloned and sequenced PV DNA from pigmented papilloma-like lesions of a diamond python (Morelia spilota spilota). This represents the first complete PV genome discovered in a Squamata host (MsPV1). It consists of 7048 nt and contains the characteristic open reading (ORF) frames E6, E7, E1, E2, L1 and L2. The L1 ORF sequence showed the highest percentage of sequence identities to human PV5 (57.9%) and Caribbean manatee (Trichechus manatus) PV1 (55.4%), thus, establishing a new clade. According to phylogenetic analysis, the MsPV1 genome clusters with PVs of mammalian rather than sauropsid hosts.

Available only for authorised users

Howley PM, Lowy DR: Papillomaviruses. In Fields Virology. Volume 2. 5th edition. Edited by: Knipe DM, Howley PM. Philadelphia: Lippincott Williams and Wikins; 2007:2299-2354.

Bernard H-U, Burk RD, Chen Z, van Doorslaer K, zur Hausen H, de Villiers EM: Classification of papillomaviruses (PVs) based on 189 PV types and proposal of taxonomic amendments. Virology 2010, 401: 70-79. 10.1016/j.virol.2010.02.002PubMedCentralCrossRefPubMed

Antonsson A, Forslund O, Ekberg H, Sterner G, Hansson B: The ubiquity and impressive genomic diversity of human skin papillomaviruses suggest a commensalic nature of these viruses. J Virol 2000, 74: 11636-11641. 10.1128/JVI.74.24.11636-11641.2000PubMedCentralCrossRefPubMed

zur Hausen H: Papillomaviruses causing cancer: evasion from host-cell control in early events in carcinogenesis. J Natl Cancer Inst 2000, 92: 690-698. 10.1093/jnci/92.9.690CrossRefPubMed

Tachezy R, Rector A, Havelkova M, Wollants E, Fiten P, Opdenakker G, Jenson AB, Sundberg JP, Van Ranst M: Avian papillomaviruses: the parrot Psittacus erithacus papillomavirus (PePV) genome has a unique organization of the early protein region and is phylogenetically related to the chaffinch papillomavirus. BMC Microbiol 2002, 2: 19-28. 10.1186/1471-2180-2-19PubMedCentralCrossRefPubMed

Terai M, DeSalle R, Burk RD: Lack of Canonical E6 and E7 Open Reading Frames in Bird Papillomaviruses: Fringella coelebs Papillomavirus and Psittacus erithacus timneh Papillomavirus. J Virol 2002, 76: 10020-10023. 10.1128/JVI.76.19.10020-10023.2002PubMedCentralCrossRefPubMed

van Doorslaer K, Sidi AO, Zanier K, Rybin V, Deryckère F, Rector A, Burke RD, Lienau EK, van Ranst M, Travé G: Identification of Unusual E6 and E7 Proteins within Avian Papillomaviruses: Cellular Localisation, Biophysical Characterisation, and Phylogenetic Analysis. J Virol 2009, 83: 8759-8770. 10.1128/JVI.01777-08PubMedCentralCrossRefPubMed

Sundeberg JP: Papillomavirus Infections in Animals. In Papillomaviruses and Human Disease. Volume 1987. Edited by: Syrjänen K, Gissmann L, Koss LG. Berlin: Springer-Verlag; 40-103.

Frye FL: Biomedical and surgical aspects of captive reptile husbandry. Krieger Publishing Co., Malabar, Florida; 1991.

10.

Greek TJ: Squamous papillomas in a colony of bearded dragons (Pogona vitticeps). Proc ARAV 2001, 161-162.

11.

Garner MM, Hernandez-Divers SM, Raymond JT: Reptile neoplasia: a retrospective study of case submissions to a specialty diagnostic service. Vet Clin N Am Exot Anim Pract 2004, 7: 653-671. 10.1016/j.cvex.2004.04.002CrossRef

12.

Herbst LH, Lenz J, Van Doorslaer K, Chen Z, Stacy BA, Wellehan JF Jr, Manire CA, Burke RD: Genomic characterization of two novel reptilian papillomaviruses, Chelonia mydas papillomavirus 1 and Caretta caretta papillomavirus 1. Virology 2009, 383: 131-135. 10.1016/j.virol.2008.09.022CrossRefPubMed

13.

Rector A, Tachezy R, Van Ranst M: A sequence-independent strategy for detection and cloning of circular DNA virus genomes by using multiply primed rolling-circle amplification. J Virol 2004, 78: 4993-4998. 10.1128/JVI.78.10.4993-4998.2004PubMedCentralCrossRefPubMed

14.

Bininda-Emonds O: transAlign: using amino acids to facilitate the multiple alignment of protein-coding DNA sequences. BMC Bioinformatics 2005, 6: 156. 10.1186/1471-2105-6-156PubMedCentralCrossRefPubMed

15.

Larkin MA, Blackshields G, Brown NP, Chenna R, McGettigan PA, McWilliam H, Valentin F, Wallace IM, Wilm A, Lopez R, Thompson JD, Gibson TJ, Higgins DG: Clustal W and Clustal × version 2.0. Bioinformatics 2007, 23: 2947-2948. 10.1093/bioinformatics/btm404CrossRefPubMed

16.

Castresana J: Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis. Mol Biol Evol 2000, 17: 540-552.CrossRefPubMed

17.

Posada D, Crandall K: MODELTEST: testing the model of DNA substitution. Bioinformatics 1998, 14: 817-818. 10.1093/bioinformatics/14.9.817CrossRefPubMed

18.

Drummond A, Rambaut A: BEAST: Bayesian evolutionary analysis by sampling trees. BMC Evol Biol 2007, 7: 214. 10.1186/1471-2148-7-214PubMedCentralCrossRefPubMed

19.

Münger K, Baldwin A, Edwards E, Hayakawa H, Nguyen C, Owens M, Grace M, Huh K: Mechanisms of human papillomavirus-induced oncogenesis. J Virol 2004, 78: 11451-11460. 10.1128/JVI.78.21.11451-11460.2004PubMedCentralCrossRefPubMed

20.

Wilson V, West M, Woytek K, Rangasamy D: Papillomavirus E1 proteins: form, function, and features. Virus Genes 2002, 24: 275-290. 10.1023/A:1015336817836CrossRefPubMed

21.

de Villiers EM, Fauquet C, Broker TR, Bernard H-U, zur Hausen H: Classification of papillomaviruses. Virology 2004, 324: 17-27. 10.1016/j.virol.2004.03.033CrossRefPubMed

22.

Bernard H-U, Calleja-Macias IE, Dunn ST: Genome variation of human papillomavirus types: phylogenetic and medical implications. Int J Cancer 2006, 118: 1071-1076. 10.1002/ijc.21655CrossRefPubMed

23.

Rector A, Lemey P, Tchetzy R, Mostmans S, Ghim S-J, Van Doorslaer K, Roelke M, Bush M, Montali RJ, Joslin J, Burk RD, Jenson AB, Sundberg JP, Shapiro B, Van Ranst M: Ancient papillomavirus-host co-speciation in Felidae. Genome Biol 2007, 8: R57. 10.1186/gb-2007-8-4-r57PubMedCentralCrossRefPubMed

24.

Gottschling M, Stamatakis A, Nindl I, Stockfleth E, Alonso A, Bravo IG: Multiple evolutionary mechanisms drive papillomavirus diversification. Mol Biol Evol 2007, 24: 1242-1258. 10.1093/molbev/msm039CrossRefPubMed

25.

Stevens H, Rector A, Bertelsen MF, Leifsson PS, Van Ranst M: Novel papillomavirus isolated from the oral mucosa of a polar bear does not cluster with other papillomaviruses of carnivores. Vet Mic 2008, 129: 108-116. 10.1016/j.vetmic.2007.11.037CrossRef

26.

Gottschling M, Göker M, Stamatakis A, Bininda-Emonds ORP, Nindl I, Bravo IG: Quantifying the phylodynamic forces driving papillomavirus evolution. Mol Biol Evo 2011, 28: 2101-2113. 10.1093/molbev/msr030CrossRef

27.

Benton MJ: Testudines: The turtles. In Vertebrate Paleontology. 3rd edition. Oxford: Blackwell Publishing Ltd; 2005:229-232.

Title: Novel snake papillomavirus does not cluster with other non-mammalian papillomaviruses
Authors: Christian E Lange
Claude Favrot
Mathias Ackermann
Jessica Gull
Elisabeth Vetsch
Kurt Tobler
Publication date: 01-12-2011
Publisher: BioMed Central
Published in: Virology Journal / Issue 1/2011
Electronic ISSN: 1743-422X
DOI: https://doi.org/10.1186/1743-422X-8-436

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Reserve your place

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin

Prof. Florian Limbourg

Prof. Anoop Chauhan

Developed by: Springer Medicine

Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 1/2011

Antibodies against outer-capsid proteins of grass carp reovirus expressed in E. coli are capable of neutralizing viral infectivity

Bioinformatics analysis of rabbit haemorrhagic disease virus genome

A 5'-proximal Stem-loop Structure of 5' Untranslated Region of Porcine Reproductive and Respiratory Syndrome Virus Genome Is Key for Virus Replication

Association of laboratory parameters with viral factors in patients with hepatitis C

Establishment of persistent infection with foot-and-mouth disease virus in BHK-21 cells

Intramuscular immunization of mice with live influenza virus is more immunogenic and offers greater protection than immunization with inactivated virus

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

At a glance: The STEP trials