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Current Pediatrics Reports

Published in:

01-12-2023

Novel Diagnostics for Pediatric Heart Transplant Rejection

Authors: Manu R. Varma, Ana L. Vasquez Choy, Rakesh Donthula, Brian Feingold

Published in: Current Pediatrics Reports | Issue 4/2023

Abstract

Purpose of Review

Diagnosis of pediatric heart transplant rejection has historically relied on endomyocardial biopsy and clinical assessment. This review will describe novel techniques that may aid and refine diagnosis of rejection.

Recent Findings

Donor-derived cell-free DNA and gene expression profiling assays provide diagnostics of rejection that are less invasive than surveillance endomyocardial biopsy. Imaging with echocardiography, cardiac magnetic resonance, and cardiac computed tomography are common for pediatric cardiology patients, and their role in detecting and monitoring rejection of heart transplants continues to be modified and expanded.

Summary

Novel diagnostic tools have the potential to lead to less invasive and more precise diagnosis of transplant rejection, ideally improving the long-term care of pediatric heart transplant recipients.

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Title: Novel Diagnostics for Pediatric Heart Transplant Rejection
Authors: Manu R. Varma
Ana L. Vasquez Choy
Rakesh Donthula
Brian Feingold
Publication date: 01-12-2023
Publisher: Springer US
Published in: Current Pediatrics Reports / Issue 4/2023
Electronic ISSN: 2167-4841
DOI: https://doi.org/10.1007/s40124-023-00310-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Novel Diagnostics for Pediatric Heart Transplant Rejection

Abstract

Purpose of Review

Recent Findings

Summary

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose of Review

Recent Findings

Summary

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